glycogen synthase kinase 3 alpha

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:119.60 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:73.70 spine:- retina:- eye:35.50 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:39.80 prostate:38 ovary:- testis:- heart:58.20 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:13.30        lung:-    bladder:- kidney:63.80 pituitary:59.20 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_017344
Gene ID 50686
Unigene ID Rn.36807
Probe set ID -
Ensembl ID ENSRNOG00000020417

Orthologous Gene

Human[2]  NM_019884
Mouse[1]  NM_001031667

Chromosomal Region

1q21  [80,505,517  -  80,514,139]

Gene Family (Interpro ID)

IPR000719  Protein kinase, catalytic domain
IPR011009  Protein kinase-like domain
IPR002290  Serine/threonine-protein kinase domain
IPR017442  Serine/threonine-protein kinase-like domain
IPR001245  Tyrosine-protein kinase, catalytic domain
IPR020635  Tyrosine-protein kinase, subgroup, catalytic domain

Link to Pubmed  (Pubmed ID)

2164470
8382613
8524413
11035810
14698990
15572200
16912034
17530463
17855351
17993264
19583853
19706605
19840222
21266584
21316358
23192081
23246341
23999152

Gene Ontology  (GO ID)

Biological Process

GO:0003214  cardiac left ventricle morphogenesis
GO:0016477  cell migration
GO:0032869  cellular response to insulin stimulus
GO:0071285  cellular response to lithium ion
GO:0071407  cellular response to organic cyclic substance
GO:0006349  genetic imprinting
GO:0005977  glycogen metabolic process
GO:0044027  hypermethylation of CpG island
GO:0008286  insulin receptor signaling pathway
GO:0046325  negative regulation of glucose import
GO:0046627  negative regulation of insulin receptor signaling pathway
GO:0032007  negative regulation of TOR signaling pathway
GO:0051348  negative regulation of transferase activity
GO:0007399  nervous system development
GO:0030819  positive regulation of cAMP biosynthetic process
GO:0045823  positive regulation of heart contraction
GO:0033138  positive regulation of peptidyl-serine phosphorylation
GO:0010800  positive regulation of peptidyl-threonine phosphorylation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0006468  protein amino acid phosphorylation
GO:0003073  regulation of systemic arterial blood pressure
GO:0007165  signal transduction
GO:0016055  Wnt receptor signaling pathway

Cellular Component

GO:0005829  cytosol

Molecular Function

GO:0005524  ATP binding
GO:0034236  protein kinase A catalytic subunit binding
GO:0004672  protein kinase activity
GO:0004674  protein serine/threonine kinase activity
GO:0050321  tau-protein kinase activity