cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:23.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:35.50 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:122.90 bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:39.80 prostate:38 ovary:- testis:- heart:135.70 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:26.60        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_131902
Gene ID 54238
Unigene ID Rn.63865
Probe set ID -
Ensembl ID ENSRNOG00000008956

Orthologous Gene

Human[4]  NM_001262, NM_078626
Mouse[1]  NM_007671, NM_078626

Chromosomal Region

5q35  [131,012,525  -  131,017,679]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

11969268
12477932

Gene Ontology  (GO ID)

Biological Process

GO:0007050  cell cycle arrest
GO:0000082  G1/S transition of mitotic cell cycle
GO:0006917  induction of apoptosis
GO:0030308  negative regulation of cell growth
GO:0008285  negative regulation of cell proliferation
GO:0042326  negative regulation of phosphorylation
GO:0048709  oligodendrocyte differentiation
GO:0000079  regulation of cyclin-dependent protein kinase activity

Cellular Component

GO:0005737  cytoplasm
GO:0005634  nucleus

Molecular Function

GO:0004861  cyclin-dependent protein kinase inhibitor activity
GO:0016301  kinase activity
GO:0019901  protein kinase binding