deleted in liver cancer 1

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:23.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:36.90 spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:113.90 ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:50.70    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID XM_341444
Gene ID 58834
Unigene ID Rn.72554
Probe set ID -
Ensembl ID -

Orthologous Gene

Human [0]  
Mouse [0]  

Chromosomal Region

16q12.2  [59,312,930  -  59,355,129]

Gene Family (Interpro ID)

IPR008936  Rho GTPase activation protein
IPR000198  RhoGAP
IPR001660  Sterile alpha motif
IPR010993  Sterile alpha motif homology
IPR011510  Sterile alpha motif, type 2
IPR013761  Sterile alpha motif-type

Link to Pubmed  (Pubmed ID)

7835339
10364218
10649492
15506980
16338927
16641100
18157946
19692654

Gene Ontology  (GO ID)

Biological Process

GO:0030036  actin cytoskeleton organization
GO:0006919  activation of caspase activity
GO:0007202  activation of phospholipase C activity
GO:0032869  cellular response to insulin stimulus
GO:0007010  cytoskeleton organization
GO:0048041  focal adhesion formation
GO:0030900  forebrain development
GO:0003007  heart morphogenesis
GO:0021575  hindbrain morphogenesis
GO:0006917  induction of apoptosis
GO:0030336  negative regulation of cell migration
GO:0008285  negative regulation of cell proliferation
GO:0035024  negative regulation of Rho protein signal transduction
GO:0051497  negative regulation of stress fiber formation
GO:0001843  neural tube closure
GO:0035307  positive regulation of protein amino acid dephosphorylation
GO:0032321  positive regulation of Rho GTPase activity
GO:0032956  regulation of actin cytoskeleton organization
GO:0008360  regulation of cell shape
GO:0007266  Rho protein signal transduction
GO:0007165  signal transduction

Cellular Component

GO:0005884  actin filament
GO:0005901  caveola
GO:0005737  cytoplasm
GO:0005925  focal adhesion
GO:0045121  membrane raft
GO:0005634  nucleus
GO:0001725  stress fiber

Molecular Function

GO:0043274  phospholipase binding
GO:0030675  Rac GTPase activator activity
GO:0005100  Rho GTPase activator activity
GO:0042169  SH2 domain binding
GO:0017166  vinculin binding