solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1

 jump to detail

Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:23.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:147.50 spine:- retina:- eye:142.20 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:78 thymus:368.70 bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:1139 placenta:119.50 prostate:189.80 ovary:114.10 testis:- heart:116.30 muscle:- esophagus:- stomach:- intestine:1465.40 colon:-     liver/hepato:26.60        lung:-    bladder:- kidney:319 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_021594
Gene ID 59114
Unigene ID Rn.35142
Probe set ID -
Ensembl ID ENSRNOG00000003232

Orthologous Gene

Human[1]  NM_004252
Mouse[3]  NM_012030

Chromosomal Region

10q32.2  [105,237,637  -  105,254,750]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

10859298
11726633
15878350
16160858
16234233
16641100
17110338
18055461
19188335
20124415
20404332
20843475
20926777
21079987
21120533
21325834
21372499
21598299
21777186
21832055
22871113
22872544
22904329
23482569

Gene Ontology  (GO ID)

Biological Process

GO:0030036  actin cytoskeleton organization
GO:0007191  activation of adenylate cyclase activity by dopamine receptor signaling pathway
GO:0060158  activation of phospholipase C activity by dopamine receptor signaling pathway
GO:0006915  apoptosis
GO:0032782  bile acid secretion
GO:0019933  cAMP-mediated signaling
GO:0030643  cellular phosphate ion homeostasis
GO:0034613  cellular protein localization
GO:0034635  glutathione transport
GO:0030033  microvillus assembly
GO:0030336  negative regulation of cell migration
GO:0008285  negative regulation of cell proliferation
GO:0070373  negative regulation of ERK1 and ERK2 cascade
GO:0014067  negative regulation of phosphoinositide 3-kinase cascade
GO:0010642  negative regulation of platelet-derived growth factor receptor signaling pathway
GO:0051898  negative regulation of protein kinase B signaling cascade
GO:0010766  negative regulation of sodium ion transport
GO:0032416  negative regulation of sodium:hydrogen antiporter activity
GO:0044062  regulation of excretion
GO:0045859  regulation of protein kinase activity
GO:0070293  renal absorption
GO:0003096  renal sodium ion transport
GO:0016055  Wnt receptor signaling pathway

Cellular Component

GO:0045177  apical part of cell
GO:0016324  apical plasma membrane
GO:0031526  brush border membrane
GO:0005813  centrosome
GO:0005737  cytoplasm
GO:0012505  endomembrane system
GO:0030175  filopodium
GO:0043231  intracellular membrane-bounded organelle
GO:0016020  membrane
GO:0045121  membrane raft
GO:0005902  microvillus
GO:0031528  microvillus membrane
GO:0005634  nucleus
GO:0005886  plasma membrane
GO:0001726  ruffle

Molecular Function

GO:0031698  beta-2 adrenergic receptor binding
GO:0008013  beta-catenin binding
GO:0017081  chloride channel regulator activity
GO:0050780  dopamine receptor binding
GO:0070851  growth factor receptor binding
GO:0030165  PDZ domain binding
GO:0019902  phosphatase binding
GO:0005515  protein binding
GO:0032403  protein complex binding
GO:0032947  protein complex scaffold
GO:0019904  protein domain specific binding
GO:0043621  protein self-association
GO:0005102  receptor binding