tuberous sclerosis 1

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:12 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_021854
Gene ID 60445
Unigene ID Rn.205837
Probe set ID -
Ensembl ID ENSRNOG00000011470

Orthologous Gene

Human[3]  NM_000368, NM_001162426, NM_001162427
Mouse[2]  NM_022887, NM_001162426, NM_001162427

Chromosomal Region

3p12  [7,645,313  -  7,672,944]

Gene Family (Interpro ID)

IPR016024  Armadillo-type fold

Link to Pubmed  (Pubmed ID)

9242607
9809973
10029074
10807585
12147258
12226091
12511557
14559897
15380067
15611338
15851513
16885148
17355907
17379185
19339977
19348060
19420259
19897899
23435171

Gene Ontology  (GO ID)

Biological Process

GO:0032862  activation of Rho GTPase activity
GO:0055007  cardiac muscle cell differentiation
GO:0030030  cell projection organization
GO:0007160  cell-matrix adhesion
GO:0021987  cerebral cortex development
GO:0009790  embryonic development
GO:0021766  hippocampus development
GO:0001822  kidney development
GO:0042552  myelination
GO:0008285  negative regulation of cell proliferation
GO:0045792  negative regulation of cell size
GO:0032007  negative regulation of TOR signaling pathway
GO:0017148  negative regulation of translation
GO:0007399  nervous system development
GO:0001843  neural tube closure
GO:0051894  positive regulation of focal adhesion formation
GO:0006813  potassium ion transport
GO:0051291  protein heterooligomerization
GO:0050821  protein stabilization
GO:0032956  regulation of actin cytoskeleton organization
GO:0001952  regulation of cell-matrix adhesion
GO:0051893  regulation of focal adhesion formation
GO:0043666  regulation of phosphoprotein phosphatase activity
GO:0045859  regulation of protein kinase activity
GO:0051492  regulation of stress fiber formation
GO:0006417  regulation of translation
GO:0032868  response to insulin stimulus
GO:0006407  rRNA export from nucleus
GO:0050808  synapse organization

Cellular Component

GO:0005884  actin filament
GO:0005938  cell cortex
GO:0005737  cytoplasm
GO:0044430  cytoskeletal part
GO:0005829  cytosol
GO:0030426  growth cone
GO:0043231  intracellular membrane-bounded organelle
GO:0030027  lamellipodium
GO:0016020  membrane
GO:0043234  protein complex
GO:0033596  TSC1-TSC2 complex

Molecular Function

GO:0051087  chaperone binding
GO:0032794  GTPase activating protein binding
GO:0030695  GTPase regulator activity
GO:0047485  protein N-terminus binding