frizzled homolog 4 (Drosophila)

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:38 ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:50.70    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_022623
Gene ID 64558
Unigene ID Rn.48736
Probe set ID -
Ensembl ID ENSRNOG00000016848

Orthologous Gene

Human[1]  NM_012193
Mouse[2]  NM_008055

Chromosomal Region

1q32  [145,953,746  -  145,957,666]

Gene Family (Interpro ID)

IPR000539  Frizzled protein
IPR020067  Frizzled-like domain
IPR017981  GPCR, family 2-like

Link to Pubmed  (Pubmed ID)

12072409
12172548
15370539
18068632
18302287

Gene Ontology  (GO ID)

Biological Process

GO:0008150  biological_process
GO:0001568  blood vessel development
GO:0007420  brain development
GO:0009790  embryonic development
GO:0031987  locomotion involved in locomotory behavior
GO:0001553  luteinization
GO:0010812  negative regulation of cell-substrate adhesion
GO:0043507  positive regulation of JUN kinase activity
GO:0051091  positive regulation of transcription factor activity
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0042701  progesterone secretion
GO:0030947  regulation of vascular endothelial growth factor receptor signaling pathway
GO:0007605  sensory perception of sound
GO:0034446  substrate adhesion-dependent cell spreading
GO:0001570  vasculogenesis
GO:0016055  Wnt receptor signaling pathway
GO:0060070  Wnt receptor signaling pathway through beta-catenin
GO:0007223  Wnt receptor signaling pathway, calcium modulating pathway

Cellular Component

GO:0042995  cell projection
GO:0009986  cell surface
GO:0005911  cell-cell junction
GO:0005575  cellular_component
GO:0005737  cytoplasm
GO:0016021  integral to membrane
GO:0005886  plasma membrane

Molecular Function

GO:0019955  cytokine binding
GO:0004930  G-protein coupled receptor activity
GO:0030165  PDZ domain binding
GO:0046982  protein heterodimerization activity
GO:0042803  protein homodimerization activity
GO:0031625  ubiquitin protein ligase binding
GO:0042813  Wnt receptor activity
GO:0017147  Wnt-protein binding