iron responsive element binding protein 2

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:12 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:78 thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:75.90 ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:127.60 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_022863
Gene ID 64831
Unigene ID Rn.101322
Probe set ID -
Ensembl ID ENSRNOG00000013271

Orthologous Gene

Human[1]  NM_004136
Mouse[1]  NM_022655

Chromosomal Region

8q24  [58,433,218  -  58,477,305]

Gene Family (Interpro ID)

IPR000573  Aconitase A/isopropylmalate dehydratase small subunit, swivel
IPR015937  Aconitase-like core
IPR015928  Aconitase/3-isopropylmalate dehydratase, swivel
IPR006249  Aconitase/iron regulatory protein 2
IPR015934  Aconitase/Iron regulatory protein 2/2-methylisocitrate dehydratase

Link to Pubmed  (Pubmed ID)

7622457
7665579
12477932
15489334
16914832
18549630
18574241
18685102
19877527
19943190
22154532
22159112

Gene Ontology  (GO ID)

Biological Process

GO:0007568  aging
GO:0006879  cellular iron ion homeostasis
GO:0071456  cellular response to hypoxia
GO:0034101  erythrocyte homeostasis
GO:0050892  intestinal absorption
GO:0055072  iron ion homeostasis
GO:0030316  osteoclast differentiation
GO:0009791  post-embryonic development
GO:0006782  protoporphyrinogen IX biosynthetic process
GO:0010468  regulation of gene expression
GO:0006417  regulation of translation
GO:0010040  response to iron(II) ion
GO:0032526  response to retinoic acid

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005739  mitochondrion

Molecular Function

GO:0051539  4 iron, 4 sulfur cluster binding
GO:0030350  iron-responsive element binding
GO:0046872  metal ion binding
GO:0003723  RNA binding