HtrA serine peptidase 1

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:155.50 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:516.20 spine:- retina:- eye:248.80 artery/aorta:714.30 vein:- lymphnode:- peripheral blood:- spleen:78 thymus:- bone marrow:- adipose:147.20 bone:156.20 skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:278.80 prostate:38 ovary:342.30 testis:82.30 heart:38.80 muscle:1063 esophagus:- stomach:- intestine:- colon:-     liver/hepato:13.30        lung:101.30    bladder:- kidney:191.40 pituitary:59.20 thyroid/parathyroid:- adrenal gland:- pancreas:113.80 breast:7042.30 salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_031721
Gene ID 65164
Unigene ID Rn.2782
Probe set ID -
Ensembl ID ENSRNOG00000020533

Orthologous Gene

Human[1]  NM_002775
Mouse[2]  NM_019564

Chromosomal Region

1q37  [190,257,874  -  190,308,326]

Gene Family (Interpro ID)

IPR001254  Peptidase S1/S6, chymotrypsin/Hap
IPR001314  Peptidase S1A, chymotrypsin
IPR008256  Peptidase S1B, glutamyl endopeptidase I
IPR001940  Peptidase S1C, HrtA/DegP2/Q/S
IPR002350  Proteinase inhibitor I1, Kazal
IPR009003  Serine/cysteine peptidase, trypsin-like

Link to Pubmed  (Pubmed ID)

12477932
15333144
17426452
18164066
18207215
18436811
18682806
19680273
19796758
19933195
20157352
21682878
21844367
22595117
22618592
22800422
22893068
23326481

Gene Ontology  (GO ID)

Biological Process

GO:0030514  negative regulation of BMP signaling pathway
GO:0030512  negative regulation of transforming growth factor beta receptor signaling pathway
GO:0006508  proteolysis
GO:0001558  regulation of cell growth

Cellular Component

GO:0005829  cytosol
GO:0031012  extracellular matrix
GO:0005576  extracellular region

Molecular Function

GO:0005520  insulin-like growth factor binding
GO:0004252  serine-type endopeptidase activity
GO:0008236  serine-type peptidase activity