transient receptor potential cation channel, subfamily V, member 4

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:195.20 skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:114.10 testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:63.80 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_023970
Gene ID 66026
Unigene ID Rn.64508
Probe set ID -
Ensembl ID ENSRNOG00000001195

Orthologous Gene

Human[2]  NM_001177428, NM_001177431, NM_001177433, NM_021625, NM_147204
Mouse[1]  NM_022017, NM_001177431, NM_001177433, NM_021625, NM_147204

Chromosomal Region

12q16  [43,226,933  -  43,265,889]

Gene Family (Interpro ID)

IPR008344  Epithelial calcium channel
IPR004729  Transient receptor potential channel
IPR008347  Vanilloid receptor
IPR008348  Vanilloid receptor 2

Link to Pubmed  (Pubmed ID)

11081638
14581619
15128858
16269659
16439673
16597741
16675722
17071727
17669489
17712480
17719182
18024594
18323527
18682499
18684885
18845910
19066426
19075100
19091909
19158342
19174160
19208258
19877445
19888909
20044482
20093626
20194297
20304685
20424166
20605796
20650893
20657843
20956320
21316269
21356247
21938744
22038643
22049072
22184014
22187434
22207590
22309793
22442563
22761937
22762361
22820913
22865090
22962011
23027348
23142541
23147107
23288842
23411787
24002225
24075884

Gene Ontology  (GO ID)

Biological Process

GO:0031532  actin cytoskeleton reorganization
GO:0007015  actin filament organization
GO:0070509  calcium ion import
GO:0006816  calcium ion transport
GO:0007043  cell-cell junction assembly
GO:0006874  cellular calcium ion homeostasis
GO:0071476  cellular hypotonic response
GO:0034605  cellular response to heat
GO:0071470  cellular response to osmotic stress
GO:0043622  cortical microtubule organization
GO:0007204  elevation of cytosolic calcium ion concentration
GO:0042538  hyperosmotic salinity response
GO:0006971  hypotonic response
GO:0046785  microtubule polymerization
GO:0010977  negative regulation of neuron projection development
GO:0007231  osmosensory signaling pathway
GO:0031117  positive regulation of microtubule depolymerization
GO:0047484  regulation of response to osmotic stress
GO:0006970  response to osmotic stress
GO:0030103  vasopressin secretion

Cellular Component

GO:0005912  adherens junction
GO:0009986  cell surface
GO:0005929  cilium
GO:0030864  cortical actin cytoskeleton
GO:0005881  cytoplasmic microtubule
GO:0031410  cytoplasmic vesicle
GO:0030175  filopodium
GO:0005925  focal adhesion
GO:0030426  growth cone
GO:0016021  integral to membrane
GO:0030027  lamellipodium
GO:0005886  plasma membrane
GO:0032587  ruffle membrane

Molecular Function

GO:0003779  actin binding
GO:0051015  actin filament binding
GO:0043014  alpha-tubulin binding
GO:0005524  ATP binding
GO:0048487  beta-tubulin binding
GO:0005262  calcium channel activity
GO:0005516  calmodulin binding
GO:0005261  cation channel activity
GO:0008017  microtubule binding
GO:0005034  osmosensor activity
GO:0005515  protein binding
GO:0019901  protein kinase binding
GO:0005080  protein kinase C binding
GO:0042169  SH2 domain binding