discoidin domain receptor tyrosine kinase 2

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:95.70 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:106.60 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:294.40 bone:195.20 skin:235.40
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:75.90 ovary:228.20 testis:- heart:19.40 muscle:- esophagus:- stomach:- intestine:- colon:289.90     liver/hepato:-        lung:152    bladder:- kidney:191.40 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID XM_001076634
Gene ID 685781
Unigene ID Rn.92730
Probe set ID -
Ensembl ID -

Orthologous Gene

Human [0]  
Mouse [0]  

Chromosomal Region

13q24  [85,801,451  -  85,846,636]

Gene Family (Interpro ID)

IPR000421  Coagulation factor 5/8 type, C-terminal
IPR008979  Galactose-binding domain-like
IPR000719  Protein kinase, catalytic domain
IPR011009  Protein kinase-like domain
IPR002290  Serine/threonine-protein kinase domain
IPR017442  Serine/threonine-protein kinase-like domain
IPR001245  Tyrosine-protein kinase, catalytic domain
IPR020635  Tyrosine-protein kinase, subgroup, catalytic domain

Link to Pubmed  (Pubmed ID)

8889548
9671320
12220173
12477932
15218324
15632090
16087782
18497308
18578992
18664364
19762078
21199726
23409069
24018687

Gene Ontology  (GO ID)

Biological Process

GO:0031214  biomineral formation
GO:0007155  cell adhesion
GO:0030199  collagen fibril organization
GO:0003416  endochondral bone growth
GO:0018108  peptidyl-tyrosine phosphorylation
GO:0008284  positive regulation of cell proliferation
GO:0090091  positive regulation of extracellular matrix disassembly
GO:0010763  positive regulation of fibroblast migration
GO:0048146  positive regulation of fibroblast proliferation
GO:0045669  positive regulation of osteoblast differentiation
GO:0045860  positive regulation of protein kinase activity
GO:0051091  positive regulation of transcription factor activity
GO:0046777  protein amino acid autophosphorylation
GO:0006468  protein amino acid phosphorylation
GO:0030500  regulation of bone mineralization
GO:0007169  transmembrane receptor protein tyrosine kinase signaling pathway

Cellular Component

GO:0016324  apical plasma membrane

Molecular Function

GO:0005524  ATP binding
GO:0005518  collagen binding
GO:0004714  transmembrane receptor protein tyrosine kinase activity