SIX homeobox 3

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:12 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:35.50 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_023990
Gene ID 78974
Unigene ID Rn.123641
Probe set ID -
Ensembl ID ENSRNOG00000024544

Orthologous Gene

Human[2]  NM_005413
Mouse[4]  NM_011381

Chromosomal Region

6q12  [9,016,302  -  9,019,163]

Gene Family (Interpro ID)

IPR001356  Homeobox
IPR009057  Homeodomain-like
IPR012287  Homeodomain-related

Link to Pubmed  (Pubmed ID)

10369266
11173923
12493766
15523651

Gene Ontology  (GO ID)

Biological Process

GO:0007420  brain development
GO:0043010  camera-type eye development
GO:0048512  circadian behavior
GO:0021536  diencephalon development
GO:0001654  eye development
GO:0021797  forebrain anterior/posterior pattern formation
GO:0060235  lens induction in camera-type eye
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0030178  negative regulation of Wnt receptor signaling pathway
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0006606  protein import into nucleus
GO:0021537  telencephalon development

Cellular Component

GO:0005634  nucleus

Molecular Function

GO:0003677  DNA binding
GO:0005102  receptor binding
GO:0003705  RNA polymerase II transcription factor activity, enhancer binding
GO:0043565  sequence-specific DNA binding
GO:0003700  transcription factor activity