hydroxysteroid (17-beta) dehydrogenase 4

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:12 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:39 skin:-
GeneChip cerebrum:6.26 cerebellum:6.79 brain stem:7.30 corpus callosum/glia:- pineal gland:- peripheral nerve:6.26 spine:- retina:- eye:5.89 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:7.72 thymus:7.78 bone marrow:6.29 adipose:- bone:- skin:-
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:39.80 prostate:- ovary:- testis:905.80 heart:77.60 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:63.80 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:- placenta:- prostate:- ovary:- testis:- heart:7.48 muscle:6.54 esophagus:- stomach:- intestine:8.33 colon:7.57 liver/hepato:- lung:- bladder:- kidney:8.34 pituitary:6.76 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_024392
Gene ID 79244
Unigene ID Rn.208215
Probe set ID S83279_g_at  [RG_U34A]
Ensembl ID ENSRNOG00000015840

Orthologous Gene

Human[1]  NM_000414, NM_001199291, NM_001199292
Mouse[2]  NM_008292, NM_001199291, NM_001199292

Chromosomal Region

18q11  [45,157,435  -  45,251,606]

Gene Family (Interpro ID)

IPR003560  2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
IPR002347  Glucose/ribitol dehydrogenase
IPR016040  NAD(P)-binding domain
IPR013968  Polyketide synthase, KR
IPR020842  Polyketide synthase/Fatty acid synthase, KR
IPR002198  Short-chain dehydrogenase/reductase SDR
IPR003033  Sterol-binding
IPR016083  Sterol-binding-like

Link to Pubmed  (Pubmed ID)

8856068
8889548
8913347
9345094
12477932
12517343
14561759
16484321

Gene Ontology  (GO ID)

Biological Process

GO:0008209  androgen metabolic process
GO:0008203  cholesterol metabolic process
GO:0008210  estrogen metabolic process
GO:0006635  fatty acid beta-oxidation
GO:0060009  Sertoli cell development
GO:0000038  very-long-chain fatty acid metabolic process

Cellular Component

GO:0043231  intracellular membrane-bounded organelle
GO:0005739  mitochondrion
GO:0005778  peroxisomal membrane
GO:0005777  peroxisome

Molecular Function

GO:0030283  3(or 17)beta-hydroxysteroid dehydrogenase activity
GO:0003857  3-hydroxyacyl-CoA dehydrogenase activity
GO:0033989  3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity
GO:0016853  isomerase activity
GO:0016508  long-chain-enoyl-CoA hydratase activity
GO:0042803  protein homodimerization activity
GO:0005102  receptor binding
GO:0032934  sterol binding