ATP-binding cassette, sub-family A (ABC1), member 2

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:191.40 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:36.90 spine:- retina:- eye:35.50 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:78 thymus:- bone marrow:- adipose:- bone:156.20 skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:265.70 ovary:228.20 testis:- heart:38.80 muscle:- esophagus:- stomach:- intestine:104.70 colon:289.90     liver/hepato:26.60        lung:-    bladder:- kidney:127.60 pituitary:118.40 thyroid/parathyroid:- adrenal gland:- pancreas:56.90 breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_024396
Gene ID 79248
Unigene ID Rn.13115
Probe set ID -
Ensembl ID ENSRNOG00000014268

Orthologous Gene

Human[4]  NM_001606, NM_212533
Mouse[1]  NM_007379, NM_212533

Chromosomal Region

3p13  [3,595,423  -  3,615,320]

Gene Family (Interpro ID)

IPR003439  ABC transporter-like
IPR003593  ATPase, AAA+ type, core

Link to Pubmed  (Pubmed ID)

10970803
12210128
12483687
16539677
22086926
22871113
24201375

Gene Ontology  (GO ID)

Biological Process

GO:0006200  ATP catabolic process
GO:0042632  cholesterol homeostasis
GO:0032383  regulation of intracellular cholesterol transport
GO:0006357  regulation of transcription from RNA polymerase II promoter
GO:0048545  response to steroid hormone stimulus
GO:0006810  transport

Cellular Component

GO:0016023  cytoplasmic membrane-bounded vesicle
GO:0005768  endosome
GO:0010008  endosome membrane
GO:0016021  integral to membrane
GO:0005765  lysosomal membrane
GO:0005764  lysosome
GO:0005815  microtubule organizing center

Molecular Function

GO:0005524  ATP binding
GO:0016887  ATPase activity