dishevelled, dsh homolog 1 (Drosophila)

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:155.50 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:156 thymus:122.90 bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:39.80 prostate:113.90 ovary:- testis:576.40 heart:58.20 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:146.30        lung:152    bladder:- kidney:191.40 pituitary:59.20 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_031820
Gene ID 83721
Unigene ID Rn.144610
Probe set ID -
Ensembl ID ENSRNOG00000019423

Orthologous Gene

Human[1]  NM_004421
Mouse[2]  NM_010091

Chromosomal Region

5q36  [172,705,951  -  172,717,626]

Gene Family (Interpro ID)

IPR000591  DEP domain
IPR015506  Dishevelled related protein
IPR008340  Dishevelled-1 protein
IPR011991  Winged helix repressor DNA-binding

Link to Pubmed  (Pubmed ID)

8644734
8856345
9298901
11113207
11354832
12477932
15256074
15608632
16478782
17027228
17212654
17558396
21718540
23160799

Gene Ontology  (GO ID)

Biological Process

GO:0048675  axon extension
GO:0007411  axon guidance
GO:0007409  axonogenesis
GO:0090103  cochlea morphogenesis
GO:0048668  collateral sprouting
GO:0060026  convergent extension
GO:0022007  convergent extension involved in neural plate elongation
GO:0060029  convergent extension involved in organogenesis
GO:0031122  cytoplasmic microtubule organization
GO:0048813  dendrite morphogenesis
GO:0001933  negative regulation of protein amino acid phosphorylation
GO:0032091  negative regulation of protein binding
GO:0006469  negative regulation of protein kinase activity
GO:0021915  neural tube development
GO:0007528  neuromuscular junction development
GO:0007269  neurotransmitter secretion
GO:0090179  planar cell polarity pathway involved in neural tube closure
GO:0010976  positive regulation of neuron projection development
GO:0032436  positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0030177  positive regulation of Wnt receptor signaling pathway
GO:0060134  prepulse inhibition
GO:0034504  protein localization in nucleus
GO:0043113  receptor clustering
GO:0001505  regulation of neurotransmitter levels
GO:0001932  regulation of protein amino acid phosphorylation
GO:0071340  skeletal muscle nicotinic acetylcholine receptor clustering
GO:0035176  social behavior
GO:0050808  synapse organization
GO:0006366  transcription from RNA polymerase II promoter
GO:0016055  Wnt receptor signaling pathway
GO:0060070  Wnt receptor signaling pathway through beta-catenin
GO:0060071  Wnt receptor signaling pathway, planar cell polarity pathway

Cellular Component

GO:0030424  axon
GO:0005938  cell cortex
GO:0043025  cell soma
GO:0030136  clathrin-coated vesicle
GO:0016023  cytoplasmic membrane-bounded vesicle
GO:0031410  cytoplasmic vesicle
GO:0005829  cytosol
GO:0030425  dendrite
GO:0030426  growth cone
GO:0016328  lateral plasma membrane
GO:0005874  microtubule
GO:0015630  microtubule cytoskeleton
GO:0045202  synapse

Molecular Function

GO:0019899  enzyme binding
GO:0005109  frizzled binding
GO:0042802  identical protein binding
GO:0019901  protein kinase binding
GO:0048365  Rac GTPase binding
GO:0004871  signal transducer activity