vascular endothelial growth factor A

jump to detail

Synonym

-

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:143.60 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:142.20 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:390 thymus:- bone marrow:- adipose:294.40 bone:390.50 skin:-
GeneChip cerebrum:4.39 cerebellum:4.71 brain stem:4.48 corpus callosum/glia:- pineal gland:- peripheral nerve:4.45 spine:- retina:- eye:4.26 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:4.30 thymus:4.07 bone marrow:4.43 adipose:- bone:- skin:-
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:238.90 prostate:75.90 ovary:228.20 testis:- heart:232.70 muscle:265.70 esophagus:- stomach:- intestine:209.30 colon:-     liver/hepato:53.20        lung:506.60    bladder:- kidney:63.80 pituitary:59.20 thyroid/parathyroid:3891.10 adrenal gland:- pancreas:284.50 breast:- salivary:-
GeneChip uterus:- placenta:- prostate:- ovary:- testis:- heart:6 muscle:5.12 esophagus:- stomach:- intestine:4.30 colon:4.11 liver/hepato:- lung:- bladder:- kidney:4.38 pituitary:4.01 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
CAGE nodata
RNA-seq nodata

IDs

Refseq ID NM_031836
Gene ID 83785
Unigene ID Rn.1923
Probe set ID M32167_g_at  [RG_U34A]
Ensembl ID ENSRNOG00000019598

Orthologous Gene

Human[14]  NM_001025366, NM_001025367, NM_001025368, NM_001025369, NM_001025370, NM_001033756, NM_001171622, NM_001171623, NM_001171624, NM_001171625, NM_001171626, NM_001171627, NM_001171628, NM_001171629, NM_001171630, NM_001204384, NM_001204385, NM_003376
Mouse[12]  NM_001025250, NM_001025257, NM_009505, NM_001025369, NM_001025370, NM_001033756, NM_001171622, NM_001171623, NM_001171624, NM_001171625, NM_001171626, NM_001171627, NM_001171628, NM_001171629, NM_001171630, NM_001204384, NM_001204385, NM_003376

Chromosomal Region

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

2320579
5135051
7706320
7738351
7768934
7846076
7876550
7933988
8064230
8344219
8859080
8889548
9852717
9916007
10215998
10229225
10342292
10541235
10554031
10652191
10751359
10878616
11078065
11163598
11352659
11397779
11585245
11744811
11799077
11839570
11861517
11901189
11914216
11919509
11934834
11940521
11981751
12002441
12006174
12007837
12046073
12086595
12089605
12174896
12181492
12195295
12208074
12230324
12234794
12368217
12376368
12387457
12444056
12477932
12483534
12515393
12540967
12541477
12563064
12571449
12590138
12606532
12631117
12633568
12665660
12692851
12761968
12800090
12881220
12900522
12930297
12937129
12946796
14519228
14529579
14561656
14635716
14635718
14643756
14660915
14663468
14664702
14670179
14693680
14696965
14718351
14742307
14753438
14962110
15031602
15031673
15034080
15050532
15050899
15063765
15084519
15086936
15094037
15126502
15131073
15137063
15150105
15156404
15161688
15166499
15178644
15180964
15187003
15195119
15219420
15249212
15257411
15258583
15267172
15289890
15303088
15312247
15467755
15470196
15477409
15491965
15521009
15610240
15613744
15653207
15681497
15685607
15687494
15726836
15732116
15734877
15739121
15754021
15764076
15770733
15774498
15785231
15800930
15832056
15838270
15851615
15879288
15879344
15883642
15885787
15956982
15965421
15993383
16010973
16038988
16044082
16077951
16115033
16139132
16160062
16164572
16192634
16203926
16230500
16231704
16388189
16392034
16394111
16410746
16411082
16413500
16423853
16426919
16440308
16517614
16549155
16597689
16601840
16603731
16617130
16633338
16636650
16672722
16712976
16723717
16733790
16734388
16741021
16788140
16793871
16816123
16818728
16901919
16931798
16959835
16973934
17035941
17083617
17162607
17175233
17175272
17188266
17272396
17275844
17349140
17360578
17369464
17369472
17434742
17446232
17450384
17457373
17467696
17482424
17485853
17505145
17513698
17531158
17569125
17572843
17574386
17576819
17581219
17586065
17588308
17591953
17597103
17600519
17614845
17626736
17654489
17718428
17726104
17881084
17888890
17889862
17890434
17905242
17914982
17917075
17924979
17983687
17992557
18006432
18019359
18043510
18060621
18060864
18072084
18097617
18174522
18197097
18205708
18206400
18209624
18221855
18272597
18288639
18303668
18304943
18314447
18321563
18326689
18344903
18354258
18374641
18390208
18395608
18407748
18408130
18434360
18454179
18468635
18495151
18497305
18503889
18533784
18562929
18593636
18614764
18617696
18622701
18632792
18644387
18645720
18655767
18689794
18708733
18728749
18758911
18772338
18798867
18803284
18818569
18834982
18937073
18957989
18973754
19005920
19013152
19013462
19032372
19042927
19048427
19059263
19060224
19064974
19087268
19130402
19150651
19178538
19185395
19203849
19212638
19241604
19285541
19288744
19328472
19357264
19383236
19397783
19407245
19435557
19473555
19483196
19509553
19513111
19524286
19567820
19575935
19576799
19587327
19623180
19626991
19695348
19696011
19705456
19722158
19723043
19728613
19733244
19734584
19755989
19783962
19816949
19915910
19932587
19934008
19948826
19995970
20001687
20015768
20030694
20039857
20045921
20056215
20093283
20097747
20107068
20107925
20116868
20139114
20193739
20197608
20199645
20237252
20335103
20362592
20368092
20406973
20417686
20432372
20453526
20457593
20562294
20572782
20586869
20599605
20599775
20605140
20619315
20629321
20630084
20631454
20696782
20697002
20698758
20705122
20730910
20731041
20736792
20797711
20823573
20860549
20921951
20962116
20972576
20980160
21054999
21092652
21092735
21098094
21115498
21162206
21171350
21180137
21186584
21192293
21192306
21211317
21211366
21243740
21263376
21268133
21269989
21271590
21311201
21325621
21343256
21378373
21385309
21388619
21458034
21487926
21505729
21528367
21530097
21560328
21613481
21636803
21640078
21643626
21732485
21747167
21750722
21789886
21801303
21818951
21863308
21890879
21911594
22094487
22104377
22129892
22136717
22170591
22174951
22191573
22206010
22229198
22245234
22271757
22307775
22326847
22332532
22336210
22379341
22382381
22445886
22455130
22467572
22499584
22507670
22519405
22562302
22568219
22577112
22579701
22615070
22645419
22658411
22707412
22716278
22771446
22797318
22814749
22824331
22884805
22906018
22907120
22922737
22927341
22932749
22944728
22949406
23015338
23069939
23089551
23106861
23149126
23171679
23221067
23226762
23268393
23269647
23279742
23303813
23324288
23337128
23356989
23378030
23379999
23411880
23416159
23441597
23444112
23456363
23483612
23562340
23603001
23608382
23624342
23639879
23693073
23707263
23740668
23745581
23788612
23838428
23888777
23901221
23936150
23951316
23972394
24012216
24022223
24076411
24115032
24228092
24356884
24387171
24464023
24472554
24491567
24559584
24626343

Gene Ontology  (GO ID)

Biological Process

GO:0032147  activation of protein kinase activity
GO:0001525  angiogenesis
GO:0048844  artery morphogenesis
GO:0002575  basophil chemotaxis
GO:0007610  behavior
GO:0001568  blood vessel development
GO:0048514  blood vessel morphogenesis
GO:0001974  blood vessel remodeling
GO:0048754  branching morphogenesis of a tube
GO:0048593  camera-type eye morphogenesis
GO:0048739  cardiac muscle fiber development
GO:0060948  cardiac vascular smooth muscle cell development
GO:0060326  cell chemotaxis
GO:0030154  cell differentiation
GO:0048469  cell maturation
GO:0016477  cell migration
GO:0002042  cell migration involved in sprouting angiogenesis
GO:0008283  cell proliferation
GO:0071456  cellular response to hypoxia
GO:0060982  coronary artery morphogenesis
GO:0003169  coronary vein morphogenesis
GO:0030855  epithelial cell differentiation
GO:0042462  eye photoreceptor cell development
GO:0040007  growth
GO:0003007  heart morphogenesis
GO:0030212  hyaluronan metabolic process
GO:0001701  in utero embryonic development
GO:0050930  induction of positive chemotaxis
GO:0001822  kidney development
GO:0007595  lactation
GO:0048286  lung alveolus development
GO:0030324  lung development
GO:0030225  macrophage differentiation
GO:0060749  mammary gland alveolus development
GO:0007498  mesoderm development
GO:0030224  monocyte differentiation
GO:0048255  mRNA stabilization
GO:0043066  negative regulation of apoptosis
GO:0045779  negative regulation of bone resorption
GO:0043154  negative regulation of caspase activity
GO:0043524  negative regulation of neuron apoptosis
GO:0043069  negative regulation of programmed cell death
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0007399  nervous system development
GO:0048666  neuron development
GO:0003151  outflow tract morphogenesis
GO:0001541  ovarian follicle development
GO:0001569  patterning of blood vessels
GO:0050918  positive chemotaxis
GO:0045766  positive regulation of angiogenesis
GO:0043536  positive regulation of blood vessel endothelial cell migration
GO:0090190  positive regulation of branching involved in ureteric bud morphogenesis
GO:0045785  positive regulation of cell adhesion
GO:0051781  positive regulation of cell division
GO:0030335  positive regulation of cell migration
GO:0090050  positive regulation of cell migration involved in sprouting angiogenesis
GO:0008284  positive regulation of cell proliferation
GO:0051272  positive regulation of cellular component movement
GO:0032793  positive regulation of CREB transcription factor activity
GO:0010595  positive regulation of endothelial cell migration
GO:0001938  positive regulation of endothelial cell proliferation
GO:0050679  positive regulation of epithelial cell proliferation
GO:0070374  positive regulation of ERK1 and ERK2 cascade
GO:0051894  positive regulation of focal adhesion formation
GO:0010628  positive regulation of gene expression
GO:0043406  positive regulation of MAP kinase activity
GO:0060754  positive regulation of mast cell chemotaxis
GO:0002053  positive regulation of mesenchymal cell proliferation
GO:0002052  positive regulation of neuroblast proliferation
GO:0033138  positive regulation of peptidyl-serine phosphorylation
GO:0050731  positive regulation of peptidyl-tyrosine phosphorylation
GO:0050927  positive regulation of positive chemotaxis
GO:0031954  positive regulation of protein amino acid autophosphorylation
GO:0001934  positive regulation of protein amino acid phosphorylation
GO:0031334  positive regulation of protein complex assembly
GO:0051897  positive regulation of protein kinase B signaling cascade
GO:0090037  positive regulation of protein kinase C signaling cascade
GO:0010740  positive regulation of protein kinase cascade
GO:0002092  positive regulation of receptor internalization
GO:0009967  positive regulation of signal transduction
GO:0048661  positive regulation of smooth muscle cell proliferation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0030949  positive regulation of vascular endothelial growth factor receptor signaling pathway
GO:0043117  positive regulation of vascular permeability
GO:0031077  post-embryonic camera-type eye development
GO:0060319  primitive erythrocyte differentiation
GO:0008360  regulation of cell shape
GO:0006357  regulation of transcription from RNA polymerase II promoter
GO:0009409  response to cold
GO:0001666  response to hypoxia
GO:0043129  surfactant homeostasis
GO:0042088  T-helper 1 type immune response
GO:0035148  tube lumen formation
GO:0048010  vascular endothelial growth factor receptor signaling pathway
GO:0001944  vasculature development

Cellular Component

GO:0005604  basement membrane
GO:0009986  cell surface
GO:0005737  cytoplasm
GO:0005615  extracellular space
GO:0016020  membrane
GO:0031988  membrane-bounded vesicle
GO:0030141  secretory granule

Molecular Function

GO:0042056  chemoattractant activity
GO:0005125  cytokine activity
GO:0001968  fibronectin binding
GO:0008083  growth factor activity
GO:0008201  heparin binding
GO:0042802  identical protein binding
GO:0005161  platelet-derived growth factor receptor binding
GO:0046982  protein heterodimerization activity
GO:0042803  protein homodimerization activity
GO:0048018  receptor agonist activity
GO:0043183  vascular endothelial growth factor receptor 1 binding
GO:0043184  vascular endothelial growth factor receptor 2 binding
GO:0005172  vascular endothelial growth factor receptor binding