wingless-type MMTV integration site family, member 4

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:35.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:35.50 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:39.80 prostate:- ovary:- testis:- heart:135.70 muscle:- esophagus:- stomach:- intestine:104.70 colon:-     liver/hepato:13.30        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:227.60 breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_053402
Gene ID 84426
Unigene ID Rn.34782
Probe set ID -
Ensembl ID ENSRNOG00000013166

Orthologous Gene

Human[1]  NM_030761
Mouse[1]  NM_009523

Chromosomal Region

5q36  [156,064,350  -  156,083,190]

Gene Family (Interpro ID)

IPR005816  Secreted growth factor Wnt protein
IPR005817  Wnt superfamily
IPR009142  Wnt-4 protein

Link to Pubmed  (Pubmed ID)

8168088
9099960
12477932
12707392
15317892
16551644
17708712
18765832
18847325
20126574
20200966
21245194
23027131
23625269

Gene Ontology  (GO ID)

Biological Process

GO:0030325  adrenal gland development
GO:0048856  anatomical structure development
GO:0006702  androgen biosynthetic process
GO:0001658  branching involved in ureteric bud morphogenesis
GO:0048754  branching morphogenesis of a tube
GO:0030154  cell differentiation
GO:0045165  cell fate commitment
GO:0071392  cellular response to estradiol stimulus
GO:0071464  cellular response to hydrostatic pressure
GO:0001838  embryonic epithelial tube formation
GO:0001837  epithelial to mesenchymal transition
GO:0090002  establishment of protein localization in plasma membrane
GO:0008585  female gonad development
GO:0030237  female sex determination
GO:0007276  gamete generation
GO:0042445  hormone metabolic process
GO:0033080  immature T cell proliferation in the thymus
GO:0001822  kidney development
GO:0001889  liver development
GO:0008584  male gonad development
GO:0060231  mesenchymal to epithelial transition
GO:0001823  mesonephros development
GO:0001656  metanephros development
GO:0043066  negative regulation of apoptosis
GO:0045596  negative regulation of cell differentiation
GO:0030336  negative regulation of cell migration
GO:0040037  negative regulation of fibroblast growth factor receptor signaling pathway
GO:0010629  negative regulation of gene expression
GO:0010894  negative regulation of steroid biosynthetic process
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0090090  negative regulation of Wnt receptor signaling pathway through beta-catenin
GO:0030182  neuron differentiation
GO:0048599  oocyte development
GO:0032349  positive regulation of aldosterone biosynthetic process
GO:0030501  positive regulation of bone mineralization
GO:0032967  positive regulation of collagen biosynthetic process
GO:0051894  positive regulation of focal adhesion formation
GO:0045836  positive regulation of meiosis
GO:0045669  positive regulation of osteoblast differentiation
GO:0032321  positive regulation of Rho GTPase activity
GO:0051496  positive regulation of stress fiber formation
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0018345  protein palmitoylation
GO:0022407  regulation of cell-cell adhesion
GO:0032355  response to estradiol stimulus
GO:0007548  sex differentiation
GO:0051145  smooth muscle cell differentiation
GO:0060126  somatotropin secreting cell differentiation
GO:0033077  T cell differentiation in the thymus
GO:0060748  tertiary branching involved in mammary gland duct morphogenesis
GO:0060129  thyroid stimulating hormone secreting cell differentiation
GO:0035239  tube morphogenesis
GO:0016055  Wnt receptor signaling pathway
GO:0060070  Wnt receptor signaling pathway through beta-catenin

Cellular Component

GO:0009986  cell surface
GO:0005737  cytoplasm
GO:0031012  extracellular matrix
GO:0005615  extracellular space
GO:0005794  Golgi apparatus
GO:0005578  proteinaceous extracellular matrix

Molecular Function

GO:0005109  frizzled binding
GO:0003674  molecular_function
GO:0003714  transcription corepressor activity