histone deacetylase 5

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:83.70 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:36.90 spine:- retina:- eye:319.90 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:78 thymus:- bone marrow:- adipose:147.20 bone:39 skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:119.50 prostate:189.80 ovary:114.10 testis:- heart:135.70 muscle:- esophagus:- stomach:- intestine:104.70 colon:289.90     liver/hepato:-        lung:101.30    bladder:- kidney:63.80 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:170.70 breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID XM_001081495
Gene ID 84580
Unigene ID Rn.79863
Probe set ID -
Ensembl ID -

Orthologous Gene

Human [0]  
Mouse [0]  

Chromosomal Region

10q32.1  [91,266,519  -  91,277,686]

Gene Family (Interpro ID)

IPR004364  Aminoacyl-tRNA synthetase, class II (D/K/N)
IPR018150  Aminoacyl-tRNA synthetase, class II (D/K/N)-like
IPR006195  Aminoacyl-tRNA synthetase, class II, conserved domain
IPR002312  Aspartyl-tRNA synthetase, class IIb
IPR017320  Histone deacetylase class II, eukaryotic
IPR000286  Histone deacetylase superfamily

Link to Pubmed  (Pubmed ID)

10640276
12477932
12896970
16221676
16767219
17011572
17823368
18292392
18632988
18768922
21255680
21954104
22360269
23161540
23480850

Gene Ontology  (GO ID)

Biological Process

GO:0071498  cellular response to fluid shear stress
GO:0006325  chromatin organization
GO:0007507  heart development
GO:0016575  histone deacetylation
GO:0033555  multicellular organismal response to stress
GO:0090051  negative regulation of cell migration involved in sprouting angiogenesis
GO:0010832  negative regulation of myotube differentiation
GO:0045668  negative regulation of osteoblast differentiation
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0002076  osteoblast development
GO:0051091  positive regulation of transcription factor activity
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0010830  regulation of myotube differentiation
GO:0043393  regulation of protein binding
GO:0048742  regulation of skeletal muscle fiber development
GO:0051153  regulation of striated muscle cell differentiation
GO:0042220  response to cocaine
GO:0042493  response to drug
GO:0006950  response to stress

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005794  Golgi apparatus
GO:0000118  histone deacetylase complex
GO:0016604  nuclear body
GO:0005730  nucleolus
GO:0005634  nucleus
GO:0043234  protein complex

Molecular Function

GO:0044212  DNA regulatory region binding
GO:0004407  histone deacetylase activity
GO:0005515  protein binding
GO:0019901  protein kinase binding
GO:0005080  protein kinase C binding
GO:0003714  transcription corepressor activity
GO:0008134  transcription factor binding
GO:0070491  transcription repressor binding