twist homolog 1 (Drosophila)

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:12 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:35.50 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:39 skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:38.80 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_053530
Gene ID 85489
Unigene ID Rn.161904
Probe set ID -
Ensembl ID ENSRNOG00000011101

Orthologous Gene

Human[2]  NM_000474
Mouse[1]  NM_011658

Chromosomal Region

6q16  [52,605,737  -  52,607,842]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

8773900
8889548
8988166
10485844
10567574
11330859
12477932
19276370
19893041

Gene Ontology  (GO ID)

Biological Process

GO:0003180  aortic valve morphogenesis
GO:0006915  apoptosis
GO:0060348  bone development
GO:0003253  cardiac neural crest cell migration involved in outflow tract morphogenesis
GO:0030154  cell differentiation
GO:0071363  cellular response to growth factor stimulus
GO:0071456  cellular response to hypoxia
GO:0060363  cranial suture morphogenesis
GO:0060900  embryonic camera-type eye formation
GO:0048701  embryonic cranial skeleton morphogenesis
GO:0042733  embryonic digit morphogenesis
GO:0035115  embryonic forelimb morphogenesis
GO:0035116  embryonic hindlimb morphogenesis
GO:0030326  embryonic limb morphogenesis
GO:0048704  embryonic skeletal system morphogenesis
GO:0003203  endocardial cushion morphogenesis
GO:0035137  hindlimb morphogenesis
GO:0001701  in utero embryonic development
GO:0003183  mitral valve morphogenesis
GO:0043066  negative regulation of apoptosis
GO:0045596  negative regulation of cell differentiation
GO:0043518  negative regulation of DNA damage response, signal transduction by p53 class mediator
GO:0035067  negative regulation of histone acetylation
GO:0033128  negative regulation of histone phosphorylation
GO:0044092  negative regulation of molecular function
GO:0045668  negative regulation of osteoblast differentiation
GO:0014067  negative regulation of phosphoinositide 3-kinase cascade
GO:0048642  negative regulation of skeletal muscle tissue development
GO:0045843  negative regulation of striated muscle tissue development
GO:0043433  negative regulation of transcription factor activity
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0032720  negative regulation of tumor necrosis factor production
GO:0001843  neural tube closure
GO:0001764  neuron migration
GO:0042476  odontogenesis
GO:0001503  ossification
GO:0001649  osteoblast differentiation
GO:0060021  palate development
GO:0050679  positive regulation of epithelial cell proliferation
GO:0010718  positive regulation of epithelial to mesenchymal transition
GO:0032000  positive regulation of fatty acid beta-oxidation
GO:0010628  positive regulation of gene expression
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0032760  positive regulation of tumor necrosis factor production
GO:0030500  regulation of bone mineralization
GO:0006366  transcription from RNA polymerase II promoter

Cellular Component

GO:0005634  nucleus

Molecular Function

GO:0043425  bHLH transcription factor binding
GO:0070888  E-box binding
GO:0003674  molecular_function
GO:0019904  protein domain specific binding
GO:0046982  protein heterodimerization activity
GO:0042803  protein homodimerization activity
GO:0003700  transcription factor activity
GO:0008134  transcription factor binding