histone deacetylase 6

詳細情報を見る

同義遺伝子名

histone deacetylase 6, HDAC6, HD6, FLJ16239, JM21, Histone deacetylase 6, KIAA0901

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

nodata

GeneChip

大脳:7.44

小脳:7.63

脳幹:7.63

脳梁:7.67

松果体:-

末梢神経:7.33

脊柱:7.58

網膜:-

目:-

動脈:7.55

静脈:6.94

リンパ節:7.42

末梢血:-

脾臓:7.29

胸腺:7.43

骨髄:7.37

脂肪:7.54

骨:-

皮膚:7.37

CAGE

大脳:3.38

小脳:-

脳幹:3.43

脳梁:3.53

松果体:4.02

末梢神経:-

脊柱:3.63

網膜:-

目:-

動脈:3.10

静脈:2.83

リンパ節:2.58

末梢血:-

脾臓:2.51

胸腺:3.10

骨髄:-

脂肪:2.52

骨:-

皮膚:-

RNA-seq

大脳:2.64

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:2.94

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:2.73

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

nodata

GeneChip

子宮:7.52

胎盤:7.74

前立腺:7.46

卵巣:7.27

精巣:8.29

心臓:7.12

骨格筋:7.17

食道:7.10

胃:7.26

腸:7.19

結腸:7.20

肝臓:8.57

肺:7.43

膀胱:-

腎臓:8.34

下垂体:8.38

甲状腺:7.54

副腎:7.46

膵臓:6.93

乳腺:7.36

唾液腺:7.31

CAGE

子宮:3.01

胎盤:2.94

前立腺:2.58

卵巣:2.87

精巣:3.03

心臓:2.73

骨格筋:2.95

食道:2.40

胃:-

腸:2.75

結腸:3.06

肝臓:3.46

肺:2.93

膀胱:1.96

腎臓:3.15

下垂体:3.66

甲状腺:2.41

副腎:-

膵臓:2.71

乳腺:3.06

唾液腺:2.50

RNA-seq

子宮:-

胎盤:-

前立腺:2.90

卵巣:3.37

精巣:3.55

心臓:1.79

骨格筋:3.24

食道:-

胃:-

腸:-

結腸:2.05

肝臓:3.16

肺:2.74

膀胱:-

腎臓:3.65

下垂体:-

甲状腺:3.13

副腎:2.76

膵臓:-

乳腺:2.84

唾液腺:-

IDs

Refseq ID	NM_006044
Gene ID	10013
Unigene ID	-
Probe set ID	206846_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000094631
GTEx ID	ENSG00000094631

オーソログ対応遺伝子

マウス[2]	NM_001130416, NM_010413
ラット[2]	NM_001130416, NM_010413

染色体

Xp11.23 [48,659,784 - 48,683,392]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR000286

Histone deacetylase superfamily

遺伝子オントロジー (GO ID)

Biological Process

GO:0070842	aggresome assembly
GO:0070301	cellular response to hydrogen peroxide
GO:0071218	cellular response to misfolded protein
GO:0016575	histone deacetylation
GO:0070846	Hsp90 deacetylation
GO:0006886	intracellular protein transport
GO:0032418	lysosome localization
GO:0016236	macroautophagy
GO:0006515	misfolded or incompletely synthesized protein catabolic process
GO:0010727	negative regulation of hydrogen peroxide metabolic process
GO:0007026	negative regulation of microtubule depolymerization
GO:0051354	negative regulation of oxidoreductase activity
GO:0043242	negative regulation of protein complex disassembly
GO:0045861	negative regulation of proteolysis
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0034983	peptidyl-lysine deacetylation
GO:0070845	polyubiquitinated misfolded protein transport
GO:0090035	positive regulation of cellular chaperone-mediated protein complex assembly
GO:0010634	positive regulation of epithelial cell migration
GO:0010870	positive regulation of receptor biosynthetic process
GO:0009967	positive regulation of signal transduction
GO:0006476	protein amino acid deacetylation
GO:0043241	protein complex disassembly
GO:0000209	protein polyubiquitination
GO:0060765	regulation of androgen receptor signaling pathway
GO:0070201	regulation of establishment of protein localization
GO:0060632	regulation of microtubule-based movement
GO:0010469	regulation of receptor activity
GO:0070848	response to growth factor stimulus
GO:0051788	response to misfolded protein
GO:0010033	response to organic substance
GO:0009636	response to toxin
GO:0006351	transcription, DNA-dependent
GO:0090042	tubulin deacetylation
GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

Cellular Component

GO:0016235	aggresome
GO:0005901	caveola
GO:0031252	cell leading edge
GO:0005737	cytoplasm
GO:0005881	cytoplasmic microtubule
GO:0005829	cytosol
GO:0030286	dynein complex
GO:0000118	histone deacetylase complex
GO:0016234	inclusion body
GO:0005874	microtubule
GO:0005875	microtubule associated complex
GO:0005730	nucleolus
GO:0005634	nucleus
GO:0048471	perinuclear region of cytoplasm

Molecular Function

GO:0003779	actin binding
GO:0043014	alpha-tubulin binding
GO:0008013	beta-catenin binding
GO:0048487	beta-tubulin binding
GO:0070840	dynein complex binding
GO:0019899	enzyme binding
GO:0004407	histone deacetylase activity
GO:0042826	histone deacetylase binding
GO:0051879	Hsp90 protein binding
GO:0008017	microtubule binding
GO:0032041	NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0046969	NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0046970	NAD-dependent histone deacetylase activity (H4-K16 specific)
GO:0031593	polyubiquitin binding
GO:0005515	protein binding
GO:0048156	tau protein binding
GO:0042903	tubulin deacetylase activity
GO:0008270	zinc ion binding

histone deacetylase 6

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function