histone deacetylase 6

詳細情報を見る

同義遺伝子名

histone deacetylase 6, HDAC6, HD6, FLJ16239, JM21, Histone deacetylase 6, KIAA0901

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST nodata
GeneChip 大脳:6.32 小脳:6.51 脳幹:6.44 脳梁:6.33 松果体:- 末梢神経:5.87 脊柱:6.17 網膜:- 目:- 動脈:6.21 静脈:6.24 リンパ節:6.07 末梢血:- 脾臓:5.89 胸腺:6.27 骨髄:6.26 脂肪:6.15 骨:- 皮膚:6.17
CAGE 大脳:3.38 小脳:- 脳幹:3.43 脳梁:3.53 松果体:4.02 末梢神経:- 脊柱:3.63 網膜:- 目:- 動脈:3.10 静脈:2.83 リンパ節:2.58 末梢血:- 脾臓:2.51 胸腺:3.10 骨髄:- 脂肪:2.52 骨:- 皮膚:-
RNA-seq 大脳:2.64 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:2.94 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:2.73 骨:- 皮膚:-
EST nodata
GeneChip 子宮:6.07 胎盤:5.81 前立腺:5.97 卵巣:6.07 精巣:6.44 心臓:6.31 骨格筋:6.51 食道:6.13 胃:6.14 腸:6.21 結腸:6.30 肝臓:6.54 肺:6.10 膀胱:- 腎臓:6.41 下垂体:6.69 甲状腺:6.06 副腎:6.35 膵臓:6.63 乳腺:5.97 唾液腺:6.20
CAGE 子宮:3.01 胎盤:2.94 前立腺:2.58 卵巣:2.87 精巣:3.03 心臓:2.73 骨格筋:2.95 食道:2.40 胃:- 腸:2.75 結腸:3.06     肝臓:3.46    肺:2.93 膀胱:1.96 腎臓:3.15 下垂体:3.66 甲状腺:2.41 副腎:- 膵臓:2.71 乳腺:3.06 唾液腺:2.50
RNA-seq 子宮:- 胎盤:- 前立腺:2.90 卵巣:3.37 精巣:3.55 心臓:1.79 骨格筋:3.24 食道:- 胃:- 腸:- 結腸:2.05     肝臓:3.16        肺:2.74    膀胱:- 腎臓:3.65 下垂体:- 甲状腺:3.13 副腎:2.76 膵臓:- 乳腺:2.84 唾液腺:-

IDs

Refseq ID NM_006044
Gene ID 10013
Unigene ID -
Probe set ID 216224_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000094631
GTEx ID ENSG00000094631

オーソログ対応遺伝子

マウス[2]  NM_001130416, NM_010413
ラット[2]  NM_001130416, NM_010413

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

9139815
9150131
10048485
10220385
10898795
11474198
11533236
11677242
11689694
11861901
11948178
12024216
12032081
12354939
12391164
12477932
12486003
12535528
12606581
12620231
12718889
12792815
14670976
14675537
14702039
14743216
15102857
15171253
15302935
15347674
15467736
15469820
15501975
15806142
15831498
15831516
15835920
15916966
15937109
15937340
15976449
16082198
16148047
16186112
16192271
16288017
16738306
16919237
16951198
16964243
17389687
17474147
17512543
17516032
17588522
17604723
17643370
17846173
17851643
18029348
18079183
18247557
18316616
18356165
18413721
18499657
18568448
18591380
18606987
18636984
18644987
18671804
18697214
18781140
18781797
18794144
18852123
18996840
19033385
19036992
19158084
19167333
19228685
19321449
19344692
19383825
19438744
19596000
19737819
19744931
19805354
19855091
19893491
19910924
19913121
19961433
20008322
20018896
20029029
20102703
20129057
20133936
20159555
20181727
20308065
20360068
20371724
20593489
20628086
20696758
20720006
20837465
20970878
21044318
21076528
21082217
21090589
21103663
21139048
21220424
21235576
21284752
21340680
21377170
21421902
21455583
21486957
21532619
21562571
21690293
21699378
21847094
21847364
21900206
21906983
21949397
21952047
21988832
22022450
22069321
22089141
22124372
22174839
22193721
22238643
22334690
22367689
22367781
22372633
22375943
22384180
22392728
22464548
22492994
22504143
22589388
22645275
22674379
22678362
22766642
22778253
22792322
22797925
22936009
22952844
22955928
22957056
22967444
22989952
22994762
23010497
23076141
23084749
23152903
23159615
23181831
23258539
23370327
23402884
23405166
23487739
23580651
23618908
23634874
23698468
23703321
23723075
23727580
23752268
23798680
23824909
23974956
24023063
24025866
24035499
24086678
24089523
24146251
24200693
24216476
24220335
24255178
24474778
24561123
24654937
24685680
24795145
24816145

遺伝子オントロジー  (GO ID)

Biological Process

GO:0070842  aggresome assembly
GO:0070301  cellular response to hydrogen peroxide
GO:0071218  cellular response to misfolded protein
GO:0016575  histone deacetylation
GO:0070846  Hsp90 deacetylation
GO:0006886  intracellular protein transport
GO:0032418  lysosome localization
GO:0016236  macroautophagy
GO:0006515  misfolded or incompletely synthesized protein catabolic process
GO:0010727  negative regulation of hydrogen peroxide metabolic process
GO:0007026  negative regulation of microtubule depolymerization
GO:0051354  negative regulation of oxidoreductase activity
GO:0043242  negative regulation of protein complex disassembly
GO:0045861  negative regulation of proteolysis
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0034983  peptidyl-lysine deacetylation
GO:0070845  polyubiquitinated misfolded protein transport
GO:0090035  positive regulation of cellular chaperone-mediated protein complex assembly
GO:0010634  positive regulation of epithelial cell migration
GO:0010870  positive regulation of receptor biosynthetic process
GO:0009967  positive regulation of signal transduction
GO:0006476  protein amino acid deacetylation
GO:0043241  protein complex disassembly
GO:0000209  protein polyubiquitination
GO:0060765  regulation of androgen receptor signaling pathway
GO:0070201  regulation of establishment of protein localization
GO:0060632  regulation of microtubule-based movement
GO:0010469  regulation of receptor activity
GO:0070848  response to growth factor stimulus
GO:0051788  response to misfolded protein
GO:0010033  response to organic substance
GO:0009636  response to toxin
GO:0006351  transcription, DNA-dependent
GO:0090042  tubulin deacetylation
GO:0043162  ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

Cellular Component

GO:0016235  aggresome
GO:0005901  caveola
GO:0031252  cell leading edge
GO:0005737  cytoplasm
GO:0005881  cytoplasmic microtubule
GO:0005829  cytosol
GO:0030286  dynein complex
GO:0000118  histone deacetylase complex
GO:0016234  inclusion body
GO:0005874  microtubule
GO:0005875  microtubule associated complex
GO:0005730  nucleolus
GO:0005634  nucleus
GO:0048471  perinuclear region of cytoplasm

Molecular Function

GO:0003779  actin binding
GO:0043014  alpha-tubulin binding
GO:0008013  beta-catenin binding
GO:0048487  beta-tubulin binding
GO:0070840  dynein complex binding
GO:0019899  enzyme binding
GO:0004407  histone deacetylase activity
GO:0042826  histone deacetylase binding
GO:0051879  Hsp90 protein binding
GO:0008017  microtubule binding
GO:0032041  NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0046969  NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0046970  NAD-dependent histone deacetylase activity (H4-K16 specific)
GO:0031593  polyubiquitin binding
GO:0005515  protein binding
GO:0048156  tau protein binding
GO:0042903  tubulin deacetylase activity
GO:0008270  zinc ion binding