nuclear receptor subfamily 1, group H, member 3

同義遺伝子名

Nuclear orphan receptor LXR-alpha, LXRA, LXR-a, Liver X receptor alpha, NR1H3, nuclear receptor subfamily 1, group H, member 3, RLD-1, Oxysterols receptor LXR-alpha

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:13

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:5.90

動脈:60

静脈:-

リンパ節:-

末梢血:637.70

脾臓:208

胸腺:64.40

骨髄:-

脂肪:363

骨:102.40

皮膚:4.80

GeneChip

大脳:4.75

小脳:4.19

脳幹:4.90

脳梁:4.85

松果体:-

末梢神経:6.39

脊柱:5.06

網膜:-

目:-

動脈:5.75

静脈:4.78

リンパ節:5.88

末梢血:-

脾臓:5.72

胸腺:4.85

骨髄:4.36

脂肪:6.71

骨:-

皮膚:5.62

CAGE

大脳:1.90

小脳:-

脳幹:2.04

脳梁:1.96

松果体:1.94

末梢神経:-

脊柱:1.93

網膜:-

目:-

動脈:2.36

静脈:3.34

リンパ節:3.23

末梢血:-

脾臓:4.05

胸腺:2.12

骨髄:-

脂肪:4.72

骨:-

皮膚:-

RNA-seq

大脳:0.39

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:1.21

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:2.41

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:27.30

胎盤:29.10

前立腺:67.60

卵巣:37.30

精巣:26

心臓:102.20

骨格筋:60.30

食道:-

胃:-

腸:64.80

結腸:33.90

肝臓:31.70

肺:58.70

膀胱:-

腎臓:83.20

下垂体:-

甲状腺:-

副腎:-

膵臓:8.90

乳腺:9.30

唾液腺:-

GeneChip

子宮:5.07

胎盤:5.84

前立腺:5.37

卵巣:4.98

精巣:6.47

心臓:4.80

骨格筋:4.62

食道:4.39

胃:5.08

腸:5.38

結腸:5.55

肝臓:6.92

肺:5.11

膀胱:-

腎臓:5.68

下垂体:4.58

甲状腺:5.34

副腎:5.44

膵臓:5.05

乳腺:5.89

唾液腺:4.70

CAGE

子宮:2.33

胎盤:3.07

前立腺:2.77

卵巣:2.33

精巣:2.97

心臓:2.35

骨格筋:1.54

食道:2.30

胃:-

腸:2.99

結腸:3.11

肝臓:3.50

肺:2.85

膀胱:2.39

腎臓:2.19

下垂体:1.17

甲状腺:2.50

副腎:-

膵臓:2.18

乳腺:3.56

唾液腺:2.12

RNA-seq

子宮:-

胎盤:-

前立腺:0.18

卵巣:0.65

精巣:0.32

心臓:0.44

骨格筋:0.18

食道:-

胃:-

腸:-

結腸:0.31

肝臓:0.10

肺:0.29

膀胱:-

腎臓:0.59

下垂体:-

甲状腺:1.14

副腎:1.76

膵臓:-

乳腺:0.87

唾液腺:-

IDs

Refseq ID	NM_001130101
Gene ID	10062
Unigene ID	Hs.438863
Probe set ID	203920_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000025434
GTEx ID	ENSG00000025434

オーソログ対応遺伝子

マウス[1]	NM_001177730, NM_013839
ラット [0]

染色体

11p11.2 [47,269,851 - 47,290,396]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR003069	Ecdysteroid receptor
IPR001723	Steroid hormone receptor
IPR001728	Thyroid hormone receptor
IPR013088	Zinc finger, NHR/GATA-type
IPR001628	Zinc finger, nuclear hormone receptor-type

遺伝子オントロジー (GO ID)

Biological Process

GO:0043277	apoptotic cell clearance
GO:0044255	cellular lipid metabolic process
GO:0071222	cellular response to lipopolysaccharide
GO:0042632	cholesterol homeostasis
GO:0010467	gene expression
GO:0055088	lipid homeostasis
GO:0010887	negative regulation of cholesterol storage
GO:0050728	negative regulation of inflammatory response
GO:0060336	negative regulation of interferon-gamma-mediated signaling pathway
GO:0032369	negative regulation of lipid transport
GO:0043031	negative regulation of macrophage activation
GO:0010745	negative regulation of macrophage derived foam cell differentiation
GO:0090188	negative regulation of pancreatic juice secretion
GO:0048550	negative regulation of pinocytosis
GO:0045861	negative regulation of proteolysis
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0032270	positive regulation of cellular protein metabolic process
GO:0010875	positive regulation of cholesterol efflux
GO:0032376	positive regulation of cholesterol transport
GO:0045723	positive regulation of fatty acid biosynthetic process
GO:0051006	positive regulation of lipoprotein lipase activity
GO:0010870	positive regulation of receptor biosynthetic process
GO:0034145	positive regulation of toll-like receptor 4 signaling pathway
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0010867	positive regulation of triglyceride biosynthetic process
GO:0042752	regulation of circadian rhythm
GO:0032570	response to progesterone stimulus
GO:0055092	sterol homeostasis
GO:0006367	transcription initiation from RNA polymerase II promoter
GO:0070328	triglyceride homeostasis

Cellular Component

GO:0000790	nuclear chromatin
GO:0005654	nucleoplasm
GO:0005634	nucleus

Molecular Function

GO:0015485	cholesterol binding
GO:0003677	DNA binding
GO:0044212	DNA regulatory region binding
GO:0004879	ligand-dependent nuclear receptor activity
GO:0005515	protein binding
GO:0043565	sequence-specific DNA binding
GO:0003707	steroid hormone receptor activity
GO:0032810	sterol response element binding
GO:0003713	transcription coactivator activity
GO:0008270	zinc ion binding

nuclear receptor subfamily 1, group H, member 3

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function