ADAM metallopeptidase domain 8

 詳細情報を見る

同義遺伝子名

CD156a antigen, ADAM metallopeptidase domain 8, CD156, A disintegrin and metalloproteinase domain 8, MGC134985, a disintegrin and metalloproteinase domain 8, Cell surface antigen MS2, ADAM8, MS2, ADAM 8 precursor

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST 大脳:3.60 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:5.90 動脈:- 静脈:- リンパ節:80.90 末梢血:145.70 脾臓:132.30 胸腺:90.20 骨髄:39.40 脂肪:- 骨:25.60 皮膚:14.40
GeneChip nodata
CAGE 大脳:0.18 小脳:- 脳幹:0.43 脳梁:0.47 松果体:0.36 末梢神経:- 脊柱:0.39 網膜:- 目:- 動脈:1.33 静脈:2.63 リンパ節:2.89 末梢血:- 脾臓:2.70 胸腺:1.57 骨髄:- 脂肪:1.44 骨:- 皮膚:-
RNA-seq nodata
殖 筋 消 肝 肺 腎 泌
EST 子宮:- 胎盤:21.90 前立腺:- 卵巣:37.30 精巣:- 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:4.90    膀胱:- 腎臓:10.40 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:18.60 唾液腺:-
GeneChip nodata
CAGE 子宮:1.05 胎盤:1.83 前立腺:1.21 卵巣:0.68 精巣:0.69 心臓:0.99 骨格筋:0.63 食道:1.08 胃:- 腸:1.46 結腸:1.68     肝臓:1.16    肺:2.51 膀胱:2.31 腎臓:0.49 下垂体:0.10 甲状腺:0.53 副腎:- 膵臓:0.58 乳腺:1.16 唾液腺:1.58
RNA-seq nodata

詳細情報

IDs

Refseq ID NM_001109000
Gene ID 101
Unigene ID Hs.501574
Probe set ID -
Ensembl ID -
GTEx ID -

オーソログ対応遺伝子

マウス [0]  
ラット [0]  

染色体

-

遺伝子ファミリー (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

9126482
10354553
12135759
12477932
12777399
15220135
15574124
15623614
16344560
16385451
17339047
17548643
17979891
18397961
18566576
18682798
18691140
18710625
18811590
19284887
19397475
19469654
19575316
19601829
19714641
19766586
20453887
20628624
21077325
21640993
21679521
21728902
21983884
22215309
22229154
22878099
22941466
22959284
22965687
23670189
24247244

遺伝子オントロジー  (GO ID)

Biological Process

GO:0001525  angiogenesis
GO:0000902  cell morphogenesis
GO:0016337  cell-cell adhesion
GO:0071456  cellular response to hypoxia
GO:0006954  inflammatory response
GO:0002523  leukocyte migration during inflammatory response
GO:0048247  lymphocyte chemotaxis
GO:0043524  negative regulation of neuron apoptosis
GO:0002675  positive regulation of acute inflammatory response
GO:0045780  positive regulation of bone resorption
GO:0045785  positive regulation of cell adhesion
GO:0051044  positive regulation of membrane protein ectodomain proteolysis
GO:0051092  positive regulation of NF-kappaB transcription factor activity
GO:0051897  positive regulation of protein kinase B signaling cascade
GO:0010954  positive regulation of protein maturation by peptide bond cleavage
GO:0050714  positive regulation of protein secretion
GO:0033089  positive regulation of T cell differentiation in the thymus
GO:0070245  positive regulation of thymocyte apoptosis
GO:0006508  proteolysis
GO:0022407  regulation of cell-cell adhesion

Cellular Component

GO:0071133  alpha9-beta1 integrin-ADAM8 complex
GO:0071065  alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex
GO:0009986  cell surface
GO:0005737  cytoplasm
GO:0032127  dense core granule membrane
GO:0005887  integral to plasma membrane
GO:0032010  phagolysosome
GO:0005886  plasma membrane
GO:0002102  podosome
GO:0042581  specific granule
GO:0070820  tertiary granule

Molecular Function

GO:0005509  calcium ion binding
GO:0050839  cell adhesion molecule binding
GO:0004222  metalloendopeptidase activity
GO:0008237  metallopeptidase activity
GO:0005515  protein binding
GO:0043621  protein self-association
GO:0008270  zinc ion binding