ADAM metallopeptidase domain 10

詳細情報を見る

同義遺伝子名

ADAM 10 precursor, kuz, A disintegrin and metalloproteinase domain 10, a disintegrin and metalloproteinase domain 10, MADM, CDw156c antigen, CD156c, Kuzbanian protein homolog, KUZ, ADAM metallopeptidase domain 10, ADAM10, HsT18717, Mammalian disintegrin-metalloprotease

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:71.10 小脳:113.30 脳幹:- 脳梁:87.50 松果体:- 末梢神経:- 脊柱:112.30 網膜:- 目:41.10 動脈:359.70 静脈:66.60 リンパ節:50.60 末梢血:54.70 脾臓:56.70 胸腺:360.70 骨髄:236.20 脂肪:80.70 骨:76.80 皮膚:72
GeneChip nodata
CAGE 大脳:3.35 小脳:- 脳幹:3.74 脳梁:3.61 松果体:3.28 末梢神経:- 脊柱:3.56 網膜:- 目:- 動脈:3.35 静脈:3.58 リンパ節:3.62 末梢血:- 脾臓:4.47 胸腺:4.30 骨髄:- 脂肪:4.10 骨:- 皮膚:-
RNA-seq nodata
EST 子宮:82 胎盤:109.30 前立腺:56.30 卵巣:74.50 精巣:43.30 心臓:25.50 骨格筋:80.40 食道:- 胃:63.70 腸:- 結腸:59.40     肝臓:84.40        肺:88    膀胱:- 腎臓:10.40 下垂体:116 甲状腺:163.70 副腎:- 膵臓:26.70 乳腺:83.60 唾液腺:-
GeneChip nodata
CAGE 子宮:3.88 胎盤:4.35 前立腺:3.70 卵巣:3.45 精巣:2.96 心臓:3.63 骨格筋:2.88 食道:3.39 胃:- 腸:3.45 結腸:3.41     肝臓:3.42    肺:4.29 膀胱:3.70 腎臓:3.85 下垂体:3.18 甲状腺:3.96 副腎:- 膵臓:2.90 乳腺:3.81 唾液腺:2.63
RNA-seq nodata

IDs

Refseq ID NM_001110000
Gene ID 102
Unigene ID Hs.578508
Probe set ID -
Ensembl ID -
GTEx ID -

オーソログ対応遺伝子

マウス [0]  
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

7593158
7822279
8694785
9016778
9305925
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10423016
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遺伝子オントロジー  (GO ID)

Biological Process

GO:0007267  cell-cell signaling
GO:0030574  collagen catabolic process
GO:0051089  constitutive protein ectodomain proteolysis
GO:0007173  epidermal growth factor receptor signaling pathway
GO:0022617  extracellular matrix disassembly
GO:0030198  extracellular matrix organization
GO:0001701  in utero embryonic development
GO:0007229  integrin-mediated signaling pathway
GO:0006509  membrane protein ectodomain proteolysis
GO:0042117  monocyte activation
GO:0007162  negative regulation of cell adhesion
GO:0007220  Notch receptor processing
GO:0007219  Notch signaling pathway
GO:0051088  PMA-inducible membrane protein ectodomain proteolysis
GO:0030307  positive regulation of cell growth
GO:0030335  positive regulation of cell migration
GO:0008284  positive regulation of cell proliferation
GO:0010820  positive regulation of T cell chemotaxis
GO:0006468  protein amino acid phosphorylation
GO:0034612  response to tumor necrosis factor

Cellular Component

GO:0009986  cell surface
GO:0005737  cytoplasm
GO:0012505  endomembrane system
GO:0005794  Golgi apparatus
GO:0005798  Golgi-associated vesicle
GO:0016021  integral to membrane
GO:0005634  nucleus
GO:0005886  plasma membrane
GO:0014069  postsynaptic density

Molecular Function

GO:0004175  endopeptidase activity
GO:0005178  integrin binding
GO:0004222  metalloendopeptidase activity
GO:0008237  metallopeptidase activity
GO:0005515  protein binding
GO:0042803  protein homodimerization activity
GO:0019901  protein kinase binding
GO:0005102  receptor binding
GO:0017124  SH3 domain binding
GO:0008270  zinc ion binding