cyclin-dependent kinase inhibitor 1B (p27, Kip1)

 詳細情報を見る

同義遺伝子名

cyclin-dependent kinase inhibitor 1B (p27, Kip1), P27KIP1, KIP1, CDKN1B, Cyclin-dependent kinase inhibitor p27, p27Kip1, CDKN4, Cyclin-dependent kinase inhibitor 1B

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST 大脳:189.60 小脳:50.40 脳幹:- 脳梁:437.40 松果体:296.70 末梢神経:214.70 脊柱:224.60 網膜:- 目:41.10 動脈:149.90 静脈:- リンパ節:101.10 末梢血:127.50 脾臓:170.20 胸腺:296.30 骨髄:19.70 脂肪:161.30 骨:76.80 皮膚:43.20
GeneChip 大脳:8.33 小脳:8.83 脳幹:8.71 脳梁:8.70 松果体:- 末梢神経:8.53 脊柱:8.40 網膜:- 目:- 動脈:8.14 静脈:7.86 リンパ節:8.22 末梢血:- 脾臓:8.57 胸腺:8.73 骨髄:8.03 脂肪:8.07 骨:- 皮膚:8.07
CAGE 大脳:4.51 小脳:- 脳幹:4.66 脳梁:4.79 松果体:4.34 末梢神経:- 脊柱:4.43 網膜:- 目:- 動脈:4.51 静脈:4.68 リンパ節:4.62 末梢血:- 脾臓:4.46 胸腺:4.77 骨髄:- 脂肪:4.56 骨:- 皮膚:-
RNA-seq 大脳:5.80 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:5.98 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:5.19 骨:- 皮膚:-
殖 筋 消 肝 肺 腎 泌
EST 子宮:182.30 胎盤:36.40 前立腺:56.30 卵巣:111.80 精巣:43.30 心臓:51.10 骨格筋:60.30 食道:- 胃:42.50 腸:64.80 結腸:25.40     肝臓:-        肺:88    膀胱:251.20 腎臓:20.80 下垂体:232 甲状腺:- 副腎:50.80 膵臓:44.50 乳腺:46.50 唾液腺:-
GeneChip 子宮:8.36 胎盤:7.80 前立腺:8.58 卵巣:8.44 精巣:7.66 心臓:7.86 骨格筋:8.30 食道:7.53 胃:7.72 腸:7.98 結腸:7.62 肝臓:7.59 肺:8.13 膀胱:- 腎臓:7.23 下垂体:7.74 甲状腺:8.25 副腎:8.06 膵臓:7.13 乳腺:8.32 唾液腺:7.62
CAGE 子宮:4.75 胎盤:3.89 前立腺:4.49 卵巣:4.54 精巣:4.16 心臓:4.15 骨格筋:4.39 食道:4.45 胃:- 腸:4.01 結腸:4.42     肝臓:3.84    肺:4.78 膀胱:4.73 腎臓:3.57 下垂体:3.95 甲状腺:4.50 副腎:- 膵臓:3.59 乳腺:5.02 唾液腺:4.16
RNA-seq 子宮:- 胎盤:- 前立腺:5.88 卵巣:5.35 精巣:5.06 心臓:3.90 骨格筋:5.32 食道:- 胃:- 腸:- 結腸:5.90     肝臓:4.09        肺:6.06    膀胱:- 腎臓:4.32 下垂体:- 甲状腺:5.23 副腎:4.71 膵臓:- 乳腺:4.90 唾液腺:-

詳細情報

IDs

Refseq ID NM_004064
Gene ID 1027
Unigene ID Hs.238990
Probe set ID 209112_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000111276
GTEx ID ENSG00000111276

オーソログ対応遺伝子

マウス[2]  NM_009875
ラット [0]  

染色体

12p13.1  [12,867,992  -  12,875,305]

遺伝子ファミリー (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

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遺伝子オントロジー  (GO ID)

Biological Process

GO:0006919  activation of caspase activity
GO:0048102  autophagic cell death
GO:0007050  cell cycle arrest
GO:0071236  cellular response to antibiotic
GO:0071285  cellular response to lithium ion
GO:0071407  cellular response to organic cyclic substance
GO:0006977  DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0007173  epidermal growth factor receptor signaling pathway
GO:0008543  fibroblast growth factor receptor signaling pathway
GO:0000082  G1/S transition of mitotic cell cycle
GO:0045087  innate immune response
GO:0048839  inner ear development
GO:0000278  mitotic cell cycle
GO:0043066  negative regulation of apoptosis
GO:0030308  negative regulation of cell growth
GO:0008285  negative regulation of cell proliferation
GO:0051271  negative regulation of cellular component movement
GO:0045736  negative regulation of cyclin-dependent protein kinase activity
GO:0060770  negative regulation of epithelial cell proliferation involved in prostate gland development
GO:0033673  negative regulation of kinase activity
GO:0045930  negative regulation of mitotic cell cycle
GO:0042326  negative regulation of phosphorylation
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0048011  nerve growth factor receptor signaling pathway
GO:0048015  phosphoinositide-mediated signaling
GO:0010942  positive regulation of cell death
GO:0008284  positive regulation of cell proliferation
GO:0031116  positive regulation of microtubule polymerization
GO:0045732  positive regulation of protein catabolic process
GO:0006813  potassium ion transport
GO:0000079  regulation of cyclin-dependent protein kinase activity
GO:0007605  sensory perception of sound

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005768  endosome
GO:0005654  nucleoplasm
GO:0005634  nucleus

Molecular Function

GO:0008656  caspase activator activity
GO:0004861  cyclin-dependent protein kinase inhibitor activity
GO:0005515  protein binding
GO:0019903  protein phosphatase binding
GO:0005072  transforming growth factor beta receptor, cytoplasmic mediator activity