nucleotide-binding oligomerization domain containing 1

詳細情報を見る

同義遺伝子名

Nod1, caspase recruitment domain family, member 4, Caspase recruitment domain-containing protein 4, CARD4, Protein Nod1, NOD1

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:7.10 小脳:25.20 脳幹:- 脳梁:29.20 松果体:- 末梢神経:61.30 脊柱:224.60 網膜:- 目:5.90 動脈:- 静脈:66.60 リンパ節:10.10 末梢血:36.40 脾臓:56.70 胸腺:12.90 骨髄:19.70 脂肪:40.30 骨:25.60 皮膚:33.60
GeneChip 大脳:6.79 小脳:6.77 脳幹:6.82 脳梁:6.79 松果体:- 末梢神経:7.13 脊柱:6.68 網膜:- 目:- 動脈:7.34 静脈:7.30 リンパ節:7.34 末梢血:- 脾臓:7.64 胸腺:6.97 骨髄:7.47 脂肪:7.41 骨:- 皮膚:7.45
CAGE 大脳:1.19 小脳:- 脳幹:1.49 脳梁:1.71 松果体:1.38 末梢神経:- 脊柱:1.89 網膜:- 目:- 動脈:2.61 静脈:2.40 リンパ節:2.30 末梢血:- 脾臓:2.62 胸腺:1.73 骨髄:- 脂肪:2.80 骨:- 皮膚:-
RNA-seq 大脳:0.85 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:2.49 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:2.99 骨:- 皮膚:-
EST 子宮:63.80 胎盤:14.60 前立腺:- 卵巣:- 精巣:13 心臓:- 骨格筋:20.10 食道:- 胃:- 腸:- 結腸:93.30     肝臓:31.70        肺:39.10    膀胱:- 腎臓:10.40 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-
GeneChip 子宮:7.04 胎盤:7.21 前立腺:6.65 卵巣:7.28 精巣:6.59 心臓:7.49 骨格筋:6.98 食道:7.15 胃:7.24 腸:7.11 結腸:7.33 肝臓:6.94 肺:7.50 膀胱:- 腎臓:6.89 下垂体:6.87 甲状腺:6.90 副腎:7.01 膵臓:6.42 乳腺:7.27 唾液腺:7.34
CAGE 子宮:2.34 胎盤:2.10 前立腺:1.96 卵巣:2.71 精巣:1.49 心臓:2.67 骨格筋:1.83 食道:2.05 胃:- 腸:1.66 結腸:2.33     肝臓:1.29    肺:2.94 膀胱:2.22 腎臓:1.53 下垂体:1.68 甲状腺:3.31 副腎:- 膵臓:1.59 乳腺:3.06 唾液腺:2.31
RNA-seq 子宮:- 胎盤:- 前立腺:2.12 卵巣:2.71 精巣:1.48 心臓:1.13 骨格筋:0.34 食道:- 胃:- 腸:- 結腸:2.16     肝臓:0.56        肺:2.91    膀胱:- 腎臓:1.47 下垂体:- 甲状腺:2.66 副腎:2.50 膵臓:- 乳腺:1.92 唾液腺:-

IDs

Refseq ID NM_006092
Gene ID 10392
Unigene ID Hs.405153
Probe set ID 221073_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000106100
GTEx ID ENSG00000106100

オーソログ対応遺伝子

マウス[1]  NM_001171007, NM_172729
ラット[1]  NM_001109236, NM_172729

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

遺伝子オントロジー  (GO ID)

Biological Process

GO:0006919  activation of caspase activity
GO:0000187  activation of MAPK activity
GO:0006915  apoptosis
GO:0006952  defense response
GO:0042742  defense response to bacterium
GO:0050830  defense response to Gram-positive bacterium
GO:0016045  detection of bacterium
GO:0009595  detection of biotic stimulus
GO:0006917  induction of apoptosis
GO:0006954  inflammatory response
GO:0045087  innate immune response
GO:0042228  interleukin-8 biosynthetic process
GO:0007254  JNK cascade
GO:0002755  MyD88-dependent toll-like receptor signaling pathway
GO:0002756  MyD88-independent toll-like receptor signaling pathway
GO:0070423  nucleotide-binding oligomerization domain containing signaling pathway
GO:0002606  positive regulation of dendritic cell antigen processing and presentation
GO:0070374  positive regulation of ERK1 and ERK2 cascade
GO:0043123  positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0032755  positive regulation of interleukin-6 production
GO:0046330  positive regulation of JNK cascade
GO:0051092  positive regulation of NF-kappaB transcription factor activity
GO:0032760  positive regulation of tumor necrosis factor production
GO:0051259  protein oligomerization
GO:0007165  signal transduction
GO:0051403  stress-activated MAPK cascade
GO:0034166  toll-like receptor 10 signaling pathway
GO:0034134  toll-like receptor 2 signaling pathway
GO:0034138  toll-like receptor 3 signaling pathway
GO:0034142  toll-like receptor 4 signaling pathway
GO:0034146  toll-like receptor 5 signaling pathway
GO:0034162  toll-like receptor 9 signaling pathway
GO:0002224  toll-like receptor signaling pathway

Cellular Component

GO:0016324  apical plasma membrane
GO:0016323  basolateral plasma membrane
GO:0005737  cytoplasm
GO:0005829  cytosol

Molecular Function

GO:0005524  ATP binding
GO:0050700  CARD domain binding
GO:0008656  caspase activator activity
GO:0042802  identical protein binding
GO:0042834  peptidoglycan binding
GO:0005515  protein binding
GO:0042803  protein homodimerization activity