peroxisome proliferator-activated receptor gamma, coactivator 1 alpha

詳細情報を見る

同義遺伝子名

coactivator 1, PGC-1(alpha), PPAR gamma coactivator 1-alpha, PPARGC1A, PPARGC-1-alpha, PPARGC1, LEM6, PGC-1-alpha, PGC1, PGC1A, PGC-1v, Ligand effect modulator 6

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:30.80 小脳:12.60 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:11.80 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:12.90 骨髄:19.70 脂肪:40.30 骨:12.80 皮膚:43.20
GeneChip 大脳:5.38 小脳:5.33 脳幹:4.97 脳梁:4.71 松果体:- 末梢神経:4.82 脊柱:4.89 網膜:- 目:- 動脈:4.54 静脈:5.32 リンパ節:4.28 末梢血:- 脾臓:4.09 胸腺:4.71 骨髄:4.29 脂肪:4.56 骨:- 皮膚:5.47
CAGE 大脳:2.40 小脳:- 脳幹:2.38 脳梁:2.97 松果体:1.76 末梢神経:- 脊柱:2.66 網膜:- 目:- 動脈:1.88 静脈:3.18 リンパ節:1.30 末梢血:- 脾臓:0.56 胸腺:1.24 骨髄:- 脂肪:3.27 骨:- 皮膚:-
RNA-seq 大脳:2.70 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:1.00 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:1.29 骨:- 皮膚:-
EST 子宮:- 胎盤:- 前立腺:11.30 卵巣:- 精巣:30.30 心臓:51.10 骨格筋:- 食道:- 胃:- 腸:- 結腸:25.40     肝臓:221.70        肺:58.70    膀胱:- 腎臓:145.60 下垂体:116 甲状腺:- 副腎:- 膵臓:17.80 乳腺:- 唾液腺:-
GeneChip 子宮:4.26 胎盤:4.38 前立腺:4.84 卵巣:4.29 精巣:4.87 心臓:6.52 骨格筋:7.77 食道:5.19 胃:4.63 腸:5.46 結腸:4.79 肝臓:7.26 肺:4.76 膀胱:- 腎臓:7.05 下垂体:4.58 甲状腺:6.58 副腎:4.70 膵臓:4.79 乳腺:4.61 唾液腺:7.20
CAGE 子宮:1.88 胎盤:0.48 前立腺:2.13 卵巣:2.12 精巣:2.58 心臓:4.06 骨格筋:5.18 食道:2.65 胃:- 腸:3.94 結腸:3.58     肝臓:4.40    肺:2.28 膀胱:2.20 腎臓:5.19 下垂体:3.07 甲状腺:4.10 副腎:- 膵臓:2.41 乳腺:1.16 唾液腺:5.28
RNA-seq 子宮:- 胎盤:- 前立腺:1.41 卵巣:0.70 精巣:1.60 心臓:4.29 骨格筋:2.77 食道:- 胃:- 腸:- 結腸:1.20     肝臓:3.11        肺:1.00    膀胱:- 腎臓:4.15 下垂体:- 甲状腺:4.29 副腎:1.36 膵臓:- 乳腺:1.13 唾液腺:-

IDs

Refseq ID NM_013261
Gene ID 10891
Unigene ID Hs.527078
Probe set ID 219195_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000109819
GTEx ID ENSG00000109819

オーソログ対応遺伝子

マウス[5]  NM_008904
ラット[1]  NM_031347

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

1258810
9529258
10412986
10558993
10585775
10643692
10669761
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遺伝子オントロジー  (GO ID)

Biological Process

GO:0030521  androgen receptor signaling pathway
GO:0050873  brown fat cell differentiation
GO:0001678  cellular glucose homeostasis
GO:0045333  cellular respiration
GO:0034599  cellular response to oxidative stress
GO:0007586  digestion
GO:0019395  fatty acid oxidation
GO:0006094  gluconeogenesis
GO:0007005  mitochondrion organization
GO:0006397  mRNA processing
GO:0043524  negative regulation of neuron apoptosis
GO:0070997  neuron death
GO:0046321  positive regulation of fatty acid oxidation
GO:0045722  positive regulation of gluconeogenesis
GO:0035066  positive regulation of histone acetylation
GO:0010822  positive regulation of mitochondrion organization
GO:0051091  positive regulation of transcription factor activity
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0006461  protein complex assembly
GO:0050821  protein stabilization
GO:0010941  regulation of cell death
GO:0022904  respiratory electron transport chain
GO:0001666  response to hypoxia
GO:0014850  response to muscle activity
GO:0042594  response to starvation
GO:0008380  RNA splicing
GO:0001659  temperature homeostasis
GO:0006367  transcription initiation from RNA polymerase II promoter

Cellular Component

GO:0005829  cytosol
GO:0005665  DNA-directed RNA polymerase II, core complex
GO:0005654  nucleoplasm
GO:0005634  nucleus
GO:0016605  PML body

Molecular Function

GO:0050681  androgen receptor binding
GO:0031490  chromatin DNA binding
GO:0003677  DNA binding
GO:0016922  ligand-dependent nuclear receptor binding
GO:0030374  ligand-dependent nuclear receptor transcription coactivator activity
GO:0000166  nucleotide binding
GO:0005515  protein binding
GO:0003723  RNA binding
GO:0003713  transcription coactivator activity
GO:0008134  transcription factor binding