adenosine A2a receptor

詳細情報を見る

同義遺伝子名

ADORA2, hA2aR, Adenosine A2a receptor, adenosine A2a receptor, RDC8, ADORA2A

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:40.30

小脳:-

脳幹:-

脳梁:175

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:23.50

動脈:60

静脈:-

リンパ節:91

末梢血:54.70

脾臓:170.20

胸腺:347.90

骨髄:-

脂肪:80.70

骨:12.80

皮膚:-

GeneChip

大脳:5.55

小脳:5.02

脳幹:4.95

脳梁:4.62

松果体:-

末梢神経:4.74

脊柱:4.67

網膜:-

目:-

動脈:5.23

静脈:5.03

リンパ節:6.24

末梢血:-

脾臓:5.90

胸腺:7.75

骨髄:6.11

脂肪:4.97

骨:-

皮膚:4.91

CAGE

大脳:1.41

小脳:-

脳幹:0.96

脳梁:1.17

松果体:0.62

末梢神経:-

脊柱:0.36

網膜:-

目:-

動脈:1.16

静脈:2.99

リンパ節:2.47

末梢血:-

脾臓:2.39

胸腺:4.21

骨髄:-

脂肪:0.55

骨:-

皮膚:-

RNA-seq

大脳:0.66

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:3.18

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:0.97

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:9.10

胎盤:-

前立腺:11.30

卵巣:37.30

精巣:13

心臓:-

骨格筋:20.10

食道:-

胃:21.20

腸:64.80

結腸:17

肝臓:21.10

肺:53.80

膀胱:-

腎臓:10.40

下垂体:-

甲状腺:-

副腎:-

膵臓:35.60

乳腺:-

唾液腺:-

GeneChip

子宮:4.77

胎盤:4.77

前立腺:4.98

卵巣:4.85

精巣:4.64

心臓:5.01

骨格筋:4.88

食道:4.89

胃:5.05

腸:5.22

結腸:4.97

肝臓:5.13

肺:6.04

膀胱:-

腎臓:5.19

下垂体:5.08

甲状腺:4.96

副腎:5.51

膵臓:5.43

乳腺:4.90

唾液腺:4.88

CAGE

子宮:0.92

胎盤:0.59

前立腺:1.11

卵巣:0.79

精巣:0.84

心臓:1.38

骨格筋:0.70

食道:0.86

胃:-

腸:1.27

結腸:1.29

肝臓:1.12

肺:1.87

膀胱:1.18

腎臓:0.95

下垂体:0.66

甲状腺:0.76

副腎:-

膵臓:0

乳腺:1.16

唾液腺:1.15

RNA-seq

子宮:-

胎盤:-

前立腺:1.11

卵巣:0.85

精巣:1.14

心臓:0.90

骨格筋:0.38

食道:-

胃:-

腸:-

結腸:0.98

肝臓:0.78

肺:3.11

膀胱:-

腎臓:1.28

下垂体:-

甲状腺:0.63

副腎:2.14

膵臓:-

乳腺:0.58

唾液腺:-

IDs

Refseq ID	NM_000675
Gene ID	135
Unigene ID	Hs.197029
Probe set ID	205013_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000128271
GTEx ID	ENSG00000128271

オーソログ対応遺伝子

マウス[2]	NM_009630
ラット [0]

染色体

22q11.23 [24,813,847 - 24,838,328]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR000276	7TM GPCR, rhodopsin-like
IPR001513	Adenosine A2A receptor
IPR001634	Adenosine receptor
IPR017452	GPCR, rhodopsin-like superfamily

遺伝子オントロジー (GO ID)

Biological Process

GO:0007190	activation of adenylate cyclase activity
GO:0007189	activation of adenylate cyclase activity by G-protein signaling pathway
GO:0007205	activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway
GO:0006915	apoptosis
GO:0048143	astrocyte activation
GO:0008015	blood circulation
GO:0007596	blood coagulation
GO:0006171	cAMP biosynthetic process
GO:0007267	cell-cell signaling
GO:0006968	cellular defense response
GO:0007417	central nervous system development
GO:0042755	eating behavior
GO:0007188	G-protein signaling, coupled to cAMP nucleotide second messenger
GO:0006954	inflammatory response
GO:0007626	locomotory behavior
GO:0046636	negative regulation of alpha-beta T cell activation
GO:0043154	negative regulation of caspase activity
GO:0008285	negative regulation of cell proliferation
GO:0050728	negative regulation of inflammatory response
GO:0040013	negative regulation of locomotion
GO:0043524	negative regulation of neuron apoptosis
GO:0006469	negative regulation of protein kinase activity
GO:0043116	negative regulation of vascular permeability
GO:0048011	nerve growth factor receptor signaling pathway
GO:0048812	neuron projection morphogenesis
GO:0006909	phagocytosis
GO:0014057	positive regulation of acetylcholine secretion
GO:0014049	positive regulation of glutamate secretion
GO:0050714	positive regulation of protein secretion
GO:0032230	positive regulation of synaptic transmission, GABAergic
GO:0051968	positive regulation of synaptic transmission, glutamatergic
GO:0060134	prepulse inhibition
GO:0051924	regulation of calcium ion transport
GO:0060079	regulation of excitatory postsynaptic membrane potential
GO:0060080	regulation of inhibitory postsynaptic membrane potential
GO:0051881	regulation of mitochondrial membrane potential
GO:0014061	regulation of norepinephrine secretion
GO:0048167	regulation of synaptic plasticity
GO:0006355	regulation of transcription, DNA-dependent
GO:0001975	response to amphetamine
GO:0031000	response to caffeine
GO:0042493	response to drug
GO:0007600	sensory perception
GO:0007271	synaptic transmission, cholinergic
GO:0001963	synaptic transmission, dopaminergic
GO:0035249	synaptic transmission, glutamatergic
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
GO:0042311	vasodilation

Cellular Component

GO:0032279	asymmetric synapse
GO:0030673	axolemma
GO:0043025	cell soma
GO:0030425	dendrite
GO:0012505	endomembrane system
GO:0005887	integral to plasma membrane
GO:0044446	intracellular organelle part
GO:0016020	membrane
GO:0005886	plasma membrane
GO:0014069	postsynaptic density
GO:0045211	postsynaptic membrane
GO:0048786	presynaptic active zone
GO:0042734	presynaptic membrane

Molecular Function

GO:0001609	adenosine receptor activity, G-protein coupled
GO:0051393	alpha-actinin binding
GO:0019899	enzyme binding
GO:0005515	protein binding
GO:0046982	protein heterodimerization activity
GO:0031802	type 5 metabotropic glutamate receptor binding

adenosine A2a receptor

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function