mitogen-activated protein kinase 14

 詳細情報を見る

同義遺伝子名

mitogen-activated protein kinase 14, MAPK14, PRKM15, CSBP, Mitogen-activated protein kinase p38 alpha, MAP kinase p38 alpha, PRKM14, RK, SAPK2A, CSBP1, Mitogen-activated protein kinase 14, MAX-interacting protein 2, CSPB1, CSAID-binding protein, p38ALPHA, Mxi2, MAP kinase MXI2, MXI2, EXIP, CSBP2

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST 大脳:- 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:12.80 皮膚:-
GeneChip 大脳:6.70 小脳:7.29 脳幹:6.28 脳梁:6.59 松果体:- 末梢神経:7.08 脊柱:6.53 網膜:- 目:- 動脈:7.16 静脈:7.14 リンパ節:7.49 末梢血:- 脾臓:7.70 胸腺:8.14 骨髄:8.91 脂肪:7.46 骨:- 皮膚:7.81
CAGE 大脳:3.30 小脳:- 脳幹:3.11 脳梁:3.23 松果体:3.25 末梢神経:- 脊柱:2.70 網膜:- 目:- 動脈:3.56 静脈:3.62 リンパ節:3.82 末梢血:- 脾臓:3.85 胸腺:3.98 骨髄:- 脂肪:3.75 骨:- 皮膚:-
RNA-seq 大脳:2.49 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:2.26 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:1.68 骨:- 皮膚:-
殖 筋 消 肝 肺 腎 泌
EST 子宮:9.10 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-
GeneChip 子宮:7.78 胎盤:7.05 前立腺:7.22 卵巣:7.52 精巣:6.48 心臓:7.11 骨格筋:7.53 食道:7.64 胃:7.24 腸:7.21 結腸:7.16 肝臓:7.42 肺:7.59 膀胱:- 腎臓:7.01 下垂体:7.16 甲状腺:7.68 副腎:7.09 膵臓:6.95 乳腺:7.52 唾液腺:7.20
CAGE 子宮:4.09 胎盤:3.64 前立腺:3.84 卵巣:3.52 精巣:3.17 心臓:3.19 骨格筋:3.22 食道:3.72 胃:- 腸:3.72 結腸:3.66     肝臓:3.70    肺:3.68 膀胱:3.72 腎臓:3.26 下垂体:3.88 甲状腺:3.61 副腎:- 膵臓:3.50 乳腺:3.67 唾液腺:3.46
RNA-seq 子宮:- 胎盤:- 前立腺:1.17 卵巣:2.28 精巣:1.13 心臓:0.46 骨格筋:0.72 食道:- 胃:- 腸:- 結腸:1.33     肝臓:1.15        肺:1.82    膀胱:- 腎臓:2.26 下垂体:- 甲状腺:2.04 副腎:2.02 膵臓:- 乳腺:1.42 唾液腺:-

詳細情報

IDs

Refseq ID NM_001315
Gene ID 1432
Unigene ID Hs.485233
Probe set ID 202530_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000112062
GTEx ID ENSG00000112062

オーソログ対応遺伝子

マウス[11]  NM_001168508, NM_001168513, NM_001168514, NM_011951
ラット [0]  

染色体

6p21.31  [35,995,488  -  36,079,013]

遺伝子ファミリー (Interpro ID)

IPR008352  MAP kinase, p38
IPR000719  Protein kinase, catalytic domain
IPR011009  Protein kinase-like domain
IPR002290  Serine/threonine-protein kinase domain
IPR017442  Serine/threonine-protein kinase-like domain
IPR001245  Tyrosine-protein kinase, catalytic domain
IPR020635  Tyrosine-protein kinase, subgroup, catalytic domain

Link to Pubmed  (Pubmed ID)

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遺伝子オントロジー  (GO ID)

Biological Process

GO:0070935  3'-UTR-mediated mRNA stabilization
GO:0000187  activation of MAPK activity
GO:0001525  angiogenesis
GO:0006915  apoptosis
GO:0007596  blood coagulation
GO:0000902  cell morphogenesis
GO:0007166  cell surface receptor linked signal transduction
GO:0006928  cellular component movement
GO:0071479  cellular response to ionizing radiation
GO:0006935  chemotaxis
GO:0002062  chondrocyte differentiation
GO:0000077  DNA damage checkpoint
GO:0042770  DNA damage response, signal transduction
GO:0019395  fatty acid oxidation
GO:0010467  gene expression
GO:0006006  glucose metabolic process
GO:0045087  innate immune response
GO:0031663  lipopolysaccharide-mediated signaling pathway
GO:0016071  mRNA metabolic process
GO:0042692  muscle cell differentiation
GO:0002755  MyD88-dependent toll-like receptor signaling pathway
GO:0002756  MyD88-independent toll-like receptor signaling pathway
GO:0048011  nerve growth factor receptor signaling pathway
GO:0030316  osteoclast differentiation
GO:0018105  peptidyl-serine phosphorylation
GO:0030168  platelet activation
GO:0043536  positive regulation of blood vessel endothelial cell migration
GO:0045648  positive regulation of erythrocyte differentiation
GO:0051149  positive regulation of muscle cell differentiation
GO:0042307  positive regulation of protein import into nucleus
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0007243  protein kinase cascade
GO:0007265  Ras protein signal transduction
GO:0051090  regulation of transcription factor activity
GO:0032495  response to muramyl dipeptide
GO:0006950  response to stress
GO:0016070  RNA metabolic process
GO:0007165  signal transduction
GO:0007519  skeletal muscle tissue development
GO:0051403  stress-activated MAPK cascade
GO:0051146  striated muscle cell differentiation
GO:0034166  toll-like receptor 10 signaling pathway
GO:0034134  toll-like receptor 2 signaling pathway
GO:0034138  toll-like receptor 3 signaling pathway
GO:0034142  toll-like receptor 4 signaling pathway
GO:0034146  toll-like receptor 5 signaling pathway
GO:0034162  toll-like receptor 9 signaling pathway
GO:0002224  toll-like receptor signaling pathway
GO:0006351  transcription, DNA-dependent
GO:0048010  vascular endothelial growth factor receptor signaling pathway

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005739  mitochondrion
GO:0005654  nucleoplasm
GO:0005634  nucleus
GO:0000922  spindle pole

Molecular Function

GO:0005524  ATP binding
GO:0004707  MAP kinase activity
GO:0004708  MAP kinase kinase activity
GO:0051525  NFAT protein binding
GO:0005515  protein binding
GO:0004674  protein serine/threonine kinase activity