colony stimulating factor 1 (macrophage)

詳細情報を見る

同義遺伝子名

Macrophage colony-stimulating factor 1 precursor, M-CSF, CSF1, MCSF, CSF-1, Lanimostim, MGC31930, colony stimulating factor 1 (macrophage)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:28.40 小脳:50.40 脳幹:- 脳梁:29.20 松果体:- 末梢神経:153.40 脊柱:- 網膜:- 目:23.50 動脈:- 静脈:- リンパ節:20.20 末梢血:- 脾臓:- 胸腺:90.20 骨髄:19.70 脂肪:- 骨:51.20 皮膚:14.40
GeneChip 大脳:5.37 小脳:5.31 脳幹:5.32 脳梁:5.68 松果体:- 末梢神経:5.66 脊柱:5.91 網膜:- 目:- 動脈:5.66 静脈:5.54 リンパ節:5.48 末梢血:- 脾臓:5.54 胸腺:5.06 骨髄:5.82 脂肪:5.74 骨:- 皮膚:5.31
CAGE 大脳:2.58 小脳:- 脳幹:3.25 脳梁:3.77 松果体:1.89 末梢神経:- 脊柱:3.47 網膜:- 目:- 動脈:3.67 静脈:3.28 リンパ節:3.05 末梢血:- 脾臓:3.32 胸腺:1.61 骨髄:- 脂肪:3.71 骨:- 皮膚:-
RNA-seq 大脳:1.88 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:4.50 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:4.16 骨:- 皮膚:-
EST 子宮:72.90 胎盤:21.90 前立腺:- 卵巣:37.30 精巣:4.30 心臓:- 骨格筋:- 食道:- 胃:21.20 腸:- 結腸:8.50     肝臓:10.60        肺:63.50    膀胱:- 腎臓:10.40 下垂体:- 甲状腺:- 副腎:- 膵臓:35.60 乳腺:27.90 唾液腺:-
GeneChip 子宮:5.14 胎盤:5.46 前立腺:4.88 卵巣:5.07 精巣:5.08 心臓:5.45 骨格筋:5.30 食道:5.20 胃:5.41 腸:5.43 結腸:5.69 肝臓:5.37 肺:5.71 膀胱:- 腎臓:5.26 下垂体:5.51 甲状腺:5.22 副腎:5.57 膵臓:6.11 乳腺:5.31 唾液腺:5.22
CAGE 子宮:2.99 胎盤:2.78 前立腺:3.28 卵巣:3.26 精巣:1.91 心臓:3.12 骨格筋:2.30 食道:2.91 胃:- 腸:2.50 結腸:3.00     肝臓:2.14    肺:3.58 膀胱:3.42 腎臓:2.26 下垂体:0.87 甲状腺:2.85 副腎:- 膵臓:2.60 乳腺:4.07 唾液腺:2.39
RNA-seq 子宮:- 胎盤:- 前立腺:4.18 卵巣:3.61 精巣:3.13 心臓:1.72 骨格筋:1.89 食道:- 胃:- 腸:- 結腸:4.31     肝臓:1.97        肺:5.20    膀胱:- 腎臓:2.63 下垂体:- 甲状腺:2.89 副腎:4.24 膵臓:- 乳腺:3.64 唾液腺:-

IDs

Refseq ID NM_000757
Gene ID 1435
Unigene ID Hs.591402
Probe set ID 207082_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000184371
GTEx ID ENSG00000184371

オーソログ対応遺伝子

マウス[11]  NM_001113529, NM_001113530, NM_007778
ラット[1]  NM_023981, NM_001113530, NM_007778

染色体

遺伝子ファミリー (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

遺伝子オントロジー  (GO ID)

Biological Process

GO:0060444  branching involved in mammary gland duct morphogenesis
GO:0030154  cell differentiation
GO:0008283  cell proliferation
GO:0030097  hemopoiesis
GO:0048873  homeostasis of number of cells within a tissue
GO:0006954  inflammatory response
GO:0045087  innate immune response
GO:0030225  macrophage differentiation
GO:0060763  mammary duct terminal end bud growth
GO:0060611  mammary gland fat development
GO:0042117  monocyte activation
GO:0042476  odontogenesis
GO:0001503  ossification
GO:0030316  osteoclast differentiation
GO:0030335  positive regulation of cell migration
GO:0008284  positive regulation of cell proliferation
GO:0001954  positive regulation of cell-matrix adhesion
GO:0032270  positive regulation of cellular protein metabolic process
GO:0010628  positive regulation of gene expression
GO:0010744  positive regulation of macrophage derived foam cell differentiation
GO:0045651  positive regulation of macrophage differentiation
GO:0045657  positive regulation of monocyte differentiation
GO:0032946  positive regulation of mononuclear cell proliferation
GO:0040018  positive regulation of multicellular organism growth
GO:0042488  positive regulation of odontogenesis of dentine-containing tooth
GO:0045672  positive regulation of osteoclast differentiation
GO:0045860  positive regulation of protein kinase activity
GO:0046579  positive regulation of Ras protein signal transduction
GO:0010743  regulation of macrophage derived foam cell differentiation
GO:0030278  regulation of ossification
GO:0003006  reproductive developmental process

Cellular Component

GO:0005615  extracellular space
GO:0016021  integral to membrane
GO:0016020  membrane
GO:0048471  perinuclear region of cytoplasm
GO:0005886  plasma membrane
GO:0043235  receptor complex

Molecular Function

GO:0005125  cytokine activity
GO:0008083  growth factor activity
GO:0005157  macrophage colony stimulating factor receptor binding
GO:0042803  protein homodimerization activity