colony stimulating factor 1 (macrophage)

詳細情報を見る

同義遺伝子名

Macrophage colony-stimulating factor 1 precursor, M-CSF, CSF1, MCSF, CSF-1, Lanimostim, MGC31930, colony stimulating factor 1 (macrophage)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:28.40 小脳:50.40 脳幹:- 脳梁:29.20 松果体:- 末梢神経:153.40 脊柱:- 網膜:- 目:23.50 動脈:- 静脈:- リンパ節:20.20 末梢血:- 脾臓:- 胸腺:90.20 骨髄:19.70 脂肪:- 骨:51.20 皮膚:14.40
GeneChip 大脳:6.02 小脳:5.80 脳幹:6.17 脳梁:6.16 松果体:- 末梢神経:6.02 脊柱:6.15 網膜:- 目:- 動脈:6.27 静脈:6.42 リンパ節:6.17 末梢血:- 脾臓:6.28 胸腺:5.14 骨髄:5.82 脂肪:6.45 骨:- 皮膚:5.96
CAGE 大脳:2.58 小脳:- 脳幹:3.25 脳梁:3.77 松果体:1.89 末梢神経:- 脊柱:3.47 網膜:- 目:- 動脈:3.67 静脈:3.28 リンパ節:3.05 末梢血:- 脾臓:3.32 胸腺:1.61 骨髄:- 脂肪:3.71 骨:- 皮膚:-
RNA-seq 大脳:1.60 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:1.91 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:1.58 骨:- 皮膚:-
EST 子宮:72.90 胎盤:21.90 前立腺:- 卵巣:37.30 精巣:4.30 心臓:- 骨格筋:- 食道:- 胃:21.20 腸:- 結腸:8.50     肝臓:10.60        肺:63.50    膀胱:- 腎臓:10.40 下垂体:- 甲状腺:- 副腎:- 膵臓:35.60 乳腺:27.90 唾液腺:-
GeneChip 子宮:5.86 胎盤:5.76 前立腺:5.71 卵巣:5.82 精巣:5.19 心臓:6.40 骨格筋:5.91 食道:5.84 胃:6.17 腸:6.07 結腸:6.33 肝臓:5.95 肺:6.22 膀胱:- 腎臓:6.02 下垂体:5.59 甲状腺:5.84 副腎:6.41 膵臓:5.80 乳腺:5.98 唾液腺:5.98
CAGE 子宮:2.99 胎盤:2.78 前立腺:3.28 卵巣:3.26 精巣:1.91 心臓:3.12 骨格筋:2.30 食道:2.91 胃:- 腸:2.50 結腸:3.00     肝臓:2.14    肺:3.58 膀胱:3.42 腎臓:2.26 下垂体:0.87 甲状腺:2.85 副腎:- 膵臓:2.60 乳腺:4.07 唾液腺:2.39
RNA-seq 子宮:- 胎盤:- 前立腺:1.40 卵巣:1.08 精巣:1.28 心臓:0.75 骨格筋:0.41 食道:- 胃:- 腸:- 結腸:1.07     肝臓:0.25        肺:1.73    膀胱:- 腎臓:0.50 下垂体:- 甲状腺:1.15 副腎:1.72 膵臓:- 乳腺:1.91 唾液腺:-

IDs

Refseq ID NM_172212
Gene ID 1435
Unigene ID Hs.591402
Probe set ID 209716_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000184371
GTEx ID ENSG00000184371

オーソログ対応遺伝子

マウス[11]  NM_001113529, NM_001113530, NM_007778
ラット[1]  NM_023981, NM_001113530, NM_007778

染色体

遺伝子ファミリー (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

遺伝子オントロジー  (GO ID)

Biological Process

GO:0060444  branching involved in mammary gland duct morphogenesis
GO:0030154  cell differentiation
GO:0008283  cell proliferation
GO:0030097  hemopoiesis
GO:0048873  homeostasis of number of cells within a tissue
GO:0006954  inflammatory response
GO:0045087  innate immune response
GO:0030225  macrophage differentiation
GO:0060763  mammary duct terminal end bud growth
GO:0060611  mammary gland fat development
GO:0042117  monocyte activation
GO:0042476  odontogenesis
GO:0001503  ossification
GO:0030316  osteoclast differentiation
GO:0030335  positive regulation of cell migration
GO:0008284  positive regulation of cell proliferation
GO:0001954  positive regulation of cell-matrix adhesion
GO:0032270  positive regulation of cellular protein metabolic process
GO:0010628  positive regulation of gene expression
GO:0010744  positive regulation of macrophage derived foam cell differentiation
GO:0045651  positive regulation of macrophage differentiation
GO:0045657  positive regulation of monocyte differentiation
GO:0032946  positive regulation of mononuclear cell proliferation
GO:0040018  positive regulation of multicellular organism growth
GO:0042488  positive regulation of odontogenesis of dentine-containing tooth
GO:0045672  positive regulation of osteoclast differentiation
GO:0045860  positive regulation of protein kinase activity
GO:0046579  positive regulation of Ras protein signal transduction
GO:0010743  regulation of macrophage derived foam cell differentiation
GO:0030278  regulation of ossification
GO:0003006  reproductive developmental process

Cellular Component

GO:0005615  extracellular space
GO:0016021  integral to membrane
GO:0016020  membrane
GO:0048471  perinuclear region of cytoplasm
GO:0005886  plasma membrane
GO:0043235  receptor complex

Molecular Function

GO:0005125  cytokine activity
GO:0008083  growth factor activity
GO:0005157  macrophage colony stimulating factor receptor binding
GO:0042803  protein homodimerization activity