NK2 transcription factor related, locus 5 (Drosophila)

同義遺伝子名

Homeobox protein CSX, Homeobox protein NK-2 homolog E, Cardiac-specific homeobox, NKX2.5, CSX, NKX2-5, cardiac-specific homeo box, CSX1, Homeobox protein Nkx-2.5, NKX2E

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:2.40

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:56.70

胸腺:-

骨髄:-

脂肪:121

骨:-

皮膚:-

GeneChip

大脳:5.38

小脳:5.29

脳幹:5.52

脳梁:5.02

松果体:-

末梢神経:4.89

脊柱:5

網膜:-

目:-

動脈:5.21

静脈:5.86

リンパ節:4.88

末梢血:-

脾臓:5.83

胸腺:4.81

骨髄:5.10

脂肪:5.08

骨:-

皮膚:5.23

CAGE

大脳:0.01

小脳:-

脳幹:0

脳梁:0

松果体:0

末梢神経:-

脊柱:0

網膜:-

目:-

動脈:0.47

静脈:1.03

リンパ節:0.31

末梢血:-

脾臓:3.43

胸腺:0

骨髄:-

脂肪:0

骨:-

皮膚:-

RNA-seq

大脳:0.02

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:0

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:0

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:370.40

骨格筋:-

食道:-

胃:-

腸:-

結腸:8.50

肝臓:-

肺:9.80

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

GeneChip

子宮:4.94

胎盤:5.13

前立腺:4.90

卵巣:4.94

精巣:5

心臓:7.25

骨格筋:5.31

食道:5.05

胃:5.07

腸:5.41

結腸:5.12

肝臓:5

肺:5.10

膀胱:-

腎臓:5.18

下垂体:5.13

甲状腺:4.89

副腎:5.14

膵臓:5.83

乳腺:4.87

唾液腺:5.05

CAGE

子宮:0

胎盤:0

前立腺:0

卵巣:0.07

精巣:0.16

心臓:4.92

骨格筋:0

食道:0.18

胃:-

腸:0

結腸:0.35

肝臓:0

肺:0

膀胱:0

腎臓:0

下垂体:0.40

甲状腺:0.32

副腎:-

膵臓:0

乳腺:0

唾液腺:0

RNA-seq

子宮:-

胎盤:-

前立腺:0

卵巣:0.01

精巣:0.11

心臓:0.29

骨格筋:0.00

食道:-

胃:-

腸:-

結腸:0

肝臓:0

肺:0

膀胱:-

腎臓:0

下垂体:-

甲状腺:0.05

副腎:0.00

膵臓:-

乳腺:0.03

唾液腺:-

IDs

Refseq ID	NM_001166176
Gene ID	1482
Unigene ID	Hs.54473
Probe set ID	206578_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000183072
GTEx ID	ENSG00000183072

オーソログ対応遺伝子

マウス[1]	NM_008700
ラット [0]

染色体

5q35.1 [172,659,112 - 172,662,360]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR001356	Homeobox
IPR009057	Homeodomain-like
IPR012287	Homeodomain-related

遺伝子オントロジー (GO ID)

Biological Process

GO:0007512	adult heart development
GO:0003278	apoptosis involved in heart morphogenesis
GO:0055014	atrial cardiac muscle cell development
GO:0060413	atrial septum morphogenesis
GO:0060928	atrioventricular node cell development
GO:0060929	atrioventricular node cell fate commitment
GO:0030509	BMP signaling pathway
GO:0003166	bundle of His development
GO:0003161	cardiac conduction system development
GO:0055007	cardiac muscle cell differentiation
GO:0060038	cardiac muscle cell proliferation
GO:0060048	cardiac muscle contraction
GO:0055008	cardiac muscle tissue morphogenesis
GO:0003168	cardiac Purkinje fiber cell differentiation
GO:0003211	cardiac ventricle formation
GO:0030154	cell differentiation
GO:0035050	embryonic heart tube development
GO:0060971	embryonic heart tube left/right pattern formation
GO:0001947	heart looping
GO:0003007	heart morphogenesis
GO:0060347	heart trabecula formation
GO:0030097	hemopoiesis
GO:0043066	negative regulation of apoptosis
GO:0010667	negative regulation of cardiac muscle cell apoptosis
GO:0010832	negative regulation of myotube differentiation
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0090090	negative regulation of Wnt receptor signaling pathway through beta-catenin
GO:0003148	outflow tract septum morphogenesis
GO:0060037	pharyngeal system development
GO:0051891	positive regulation of cardioblast differentiation
GO:0008284	positive regulation of cell proliferation
GO:0045823	positive regulation of heart contraction
GO:0045666	positive regulation of neuron differentiation
GO:0010765	positive regulation of sodium ion transport
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter
GO:0010735	positive regulation of transcription via serum response element binding
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0003342	proepicardium development
GO:0003350	pulmonary myocardium development
GO:0060043	regulation of cardiac muscle cell proliferation
GO:0055117	regulation of cardiac muscle contraction
GO:0003221	right ventricular cardiac muscle tissue morphogenesis
GO:0045214	sarcomere organization
GO:0003285	septum secundum development
GO:0048536	spleen development
GO:0030878	thyroid gland development
GO:0001570	vasculogenesis
GO:0055015	ventricular cardiac muscle cell development
GO:0055005	ventricular cardiac myofibril development
GO:0060412	ventricular septum morphogenesis
GO:0003222	ventricular trabecular myocardium morphogenesis
GO:0060070	Wnt receptor signaling pathway through beta-catenin

Cellular Component

GO:0005737	cytoplasm
GO:0005634	nucleus
GO:0005667	transcription factor complex

Molecular Function

GO:0003682	chromatin binding
GO:0003677	DNA binding
GO:0044212	DNA regulatory region binding
GO:0005515	protein binding
GO:0046982	protein heterodimerization activity
GO:0042803	protein homodimerization activity
GO:0003705	RNA polymerase II transcription factor activity, enhancer binding
GO:0043565	sequence-specific DNA binding
GO:0010736	serum response element binding
GO:0003700	transcription factor activity
GO:0008134	transcription factor binding

NK2 transcription factor related, locus 5 (Drosophila)

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function