adrenergic, alpha-2A-, receptor

同義遺伝子名

Alpha-2A adrenoceptor, Alpha-2A adrenergic receptor, ZNF32, Alpha-2A adrenoreceptor, ALPHA2AAR, ADRA2R, ADRA2A, adrenergic, alpha-2A-, receptor, Alpha-2AAR, Alpha-2 adrenergic receptor subtype C10, ADRA2, ADRAR

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:13

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:92

脊柱:-

網膜:-

目:41.10

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

GeneChip

大脳:4.54

小脳:4.77

脳幹:4.24

脳梁:4.03

松果体:-

末梢神経:5.23

脊柱:4.60

網膜:-

目:-

動脈:5.30

静脈:5.42

リンパ節:6.83

末梢血:-

脾臓:7.21

胸腺:3.75

骨髄:4.09

脂肪:7.15

骨:-

皮膚:5.42

CAGE

大脳:1.82

小脳:-

脳幹:1.57

脳梁:1.68

松果体:1.23

末梢神経:-

脊柱:1.77

網膜:-

目:-

動脈:2.85

静脈:3.59

リンパ節:4.16

末梢血:-

脾臓:4.74

胸腺:0.71

骨髄:-

脂肪:4.49

骨:-

皮膚:-

RNA-seq

大脳:0.89

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:4.77

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:3.94

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:18.20

胎盤:14.60

前立腺:11.30

卵巣:74.50

精巣:4.30

心臓:51.10

骨格筋:-

食道:-

胃:-

腸:-

結腸:-

肝臓:-

肺:-

膀胱:-

腎臓:10.40

下垂体:-

甲状腺:-

副腎:50.80

膵臓:53.30

乳腺:18.60

唾液腺:-

GeneChip

子宮:6

胎盤:5.04

前立腺:4.59

卵巣:5.50

精巣:4.79

心臓:4.83

骨格筋:3.89

食道:4.87

胃:5.41

腸:6.02

結腸:5.92

肝臓:3.88

肺:4.45

膀胱:-

腎臓:4.72

下垂体:4.29

甲状腺:5.28

副腎:4.49

膵臓:5.83

乳腺:6.58

唾液腺:4.12

CAGE

子宮:4.21

胎盤:2.36

前立腺:3.75

卵巣:3.61

精巣:2.58

心臓:1.87

骨格筋:1.29

食道:2.30

胃:-

腸:2.96

結腸:3.17

肝臓:1.25

肺:2.28

膀胱:3.66

腎臓:1.70

下垂体:1.23

甲状腺:2.33

副腎:-

膵臓:4.35

乳腺:4.56

唾液腺:2.01

RNA-seq

子宮:-

胎盤:-

前立腺:2.61

卵巣:3.26

精巣:2.47

心臓:0.26

骨格筋:0.31

食道:-

胃:-

腸:-

結腸:1.89

肝臓:0.49

肺:1.34

膀胱:-

腎臓:0.53

下垂体:-

甲状腺:1.39

副腎:3.94

膵臓:-

乳腺:4.94

唾液腺:-

IDs

Refseq ID	NM_000681
Gene ID	150
Unigene ID	Hs.249159
Probe set ID	209869_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000150594
GTEx ID	ENSG00000150594

オーソログ対応遺伝子

マウス[1]	NM_007417
ラット[1]	NM_007417

染色体

10q25.2 [112,836,790 - 112,840,658]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR000276	7TM GPCR, rhodopsin-like
IPR002233	Adrenergic receptor
IPR001946	Adrenergic receptor, alpha-2A
IPR015695	Adrenergic receptor, alpha-2A/2B/2C
IPR017452	GPCR, rhodopsin-like superfamily
IPR000995	Muscarinic acetylcholine receptor

遺伝子オントロジー (GO ID)

Biological Process

GO:0030036	actin cytoskeleton organization
GO:0032147	activation of protein kinase activity
GO:0032148	activation of protein kinase B activity
GO:0002526	acute inflammatory response
GO:0007596	blood coagulation
GO:0006928	cellular component movement
GO:0032870	cellular response to hormone stimulus
GO:0006260	DNA replication
GO:0006112	energy reserve metabolic process
GO:0042596	fear response
GO:0007565	female pregnancy
GO:0007186	G-protein coupled receptor protein signaling pathway
GO:0042593	glucose homeostasis
GO:0050892	intestinal absorption
GO:0007194	negative regulation of adenylate cyclase activity
GO:0051926	negative regulation of calcium ion transport
GO:0045955	negative regulation of calcium ion-dependent exocytosis
GO:0030818	negative regulation of cAMP biosynthetic process
GO:0032811	negative regulation of epinephrine secretion
GO:0046676	negative regulation of insulin secretion
GO:0050995	negative regulation of lipid catabolic process
GO:0010700	negative regulation of norepinephrine secretion
GO:0070473	negative regulation of uterine smooth muscle contraction
GO:0030168	platelet activation
GO:0030335	positive regulation of cell migration
GO:0008284	positive regulation of cell proliferation
GO:0001819	positive regulation of cytokine production
GO:0045741	positive regulation of epidermal growth factor receptor activity
GO:0043406	positive regulation of MAP kinase activity
GO:0051044	positive regulation of membrane protein ectodomain proteolysis
GO:0043268	positive regulation of potassium ion transport
GO:0045909	positive regulation of vasodilation
GO:0007265	Ras protein signal transduction
GO:0050796	regulation of insulin secretion
GO:0019229	regulation of vasoconstriction
GO:0007266	Rho protein signal transduction
GO:0007165	signal transduction
GO:0050955	thermoception

Cellular Component

GO:0016323	basolateral plasma membrane
GO:0005737	cytoplasm
GO:0005887	integral to plasma membrane
GO:0005886	plasma membrane
GO:0043235	receptor complex
GO:0045202	synapse

Molecular Function

GO:0031692	alpha-1B adrenergic receptor binding
GO:0031696	alpha-2C adrenergic receptor binding
GO:0004938	alpha2-adrenergic receptor activity
GO:0051379	epinephrine binding
GO:0032795	heterotrimeric G-protein binding
GO:0051380	norepinephrine binding
GO:0005515	protein binding
GO:0046982	protein heterodimerization activity
GO:0042803	protein homodimerization activity
GO:0019901	protein kinase binding
GO:0031996	thioesterase binding

adrenergic, alpha-2A-, receptor

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function