disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)



DAB2, DOC2, Disabled homolog 2, Differentially expressed protein 2, DOC-2

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。


EST 大脳:88.90 小脳:88.20 脳幹:- 脳梁:437.40 松果体:- 末梢神経:368.10 脊柱:112.30 網膜:237.30 目:94 動脈:569.50 静脈:199.90 リンパ節:10.10 末梢血:200.40 脾臓:226.90 胸腺:77.30 骨髄:137.80 脂肪:121 骨:460.60 皮膚:369.60
GeneChip 大脳:5.57 小脳:6.22 脳幹:5.77 脳梁:5.69 松果体:- 末梢神経:7.09 脊柱:6.26 網膜:- 目:- 動脈:7.47 静脈:7.77 リンパ節:7.80 末梢血:- 脾臓:8.04 胸腺:6.86 骨髄:6.47 脂肪:8.43 骨:- 皮膚:7.73
CAGE 大脳:2.57 小脳:- 脳幹:2.91 脳梁:3.02 松果体:2.59 末梢神経:- 脊柱:3.36 網膜:- 目:- 動脈:4.28 静脈:4.74 リンパ節:4.30 末梢血:- 脾臓:4.26 胸腺:3.46 骨髄:- 脂肪:5.24 骨:- 皮膚:-
RNA-seq 大脳:1.88 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:4.45 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:5.76 骨:- 皮膚:-
EST 子宮:136.70 胎盤:921.70 前立腺:33.80 卵巣:111.80 精巣:47.60 心臓:242.70 骨格筋:80.40 食道:- 胃:21.20 腸:129.60 結腸:50.90     肝臓:1235        肺:136.90    膀胱:- 腎臓:509.50 下垂体:- 甲状腺:- 副腎:304.70 膵臓:88.90 乳腺:204.40 唾液腺:328.40
GeneChip 子宮:7.99 胎盤:10.99 前立腺:6.62 卵巣:7.82 精巣:5.58 心臓:7.30 骨格筋:6.25 食道:6.48 胃:6.88 腸:7.20 結腸:6.97 肝臓:6.64 肺:8.19 膀胱:- 腎臓:9.38 下垂体:5.84 甲状腺:7.03 副腎:9.64 膵臓:7.08 乳腺:7.85 唾液腺:7.10
CAGE 子宮:4.22 胎盤:6.20 前立腺:3.93 卵巣:3.82 精巣:3.44 心臓:4.06 骨格筋:3.15 食道:3.72 胃:- 腸:3.27 結腸:3.90     肝臓:2.75    肺:4.65 膀胱:4.20 腎臓:5.86 下垂体:2.42 甲状腺:3.60 副腎:- 膵臓:3.71 乳腺:4.52 唾液腺:4.20
RNA-seq 子宮:- 胎盤:- 前立腺:3.95 卵巣:4.19 精巣:4.15 心臓:2.98 骨格筋:2.37 食道:- 胃:- 腸:- 結腸:3.94     肝臓:2.20        肺:4.87    膀胱:- 腎臓:5.96 下垂体:- 甲状腺:3.67 副腎:4.58 膵臓:- 乳腺:4.78 唾液腺:-

遺伝子オントロジー  (GO ID)

Biological Process

GO:0007257  activation of JUN kinase activity
GO:0006915  apoptosis
GO:0000904  cell morphogenesis involved in differentiation
GO:0008283  cell proliferation
GO:0048268  clathrin coat assembly
GO:0007492  endoderm development
GO:0007588  excretion
GO:0001701  in utero embryonic development
GO:0016044  membrane organization
GO:0030099  myeloid cell differentiation
GO:0060766  negative regulation of androgen receptor signaling pathway
GO:0043066  negative regulation of apoptosis
GO:0032091  negative regulation of protein binding
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0090090  negative regulation of Wnt receptor signaling pathway through beta-catenin
GO:0006907  pinocytosis
GO:0030335  positive regulation of cell migration
GO:0045807  positive regulation of endocytosis
GO:0010718  positive regulation of epithelial to mesenchymal transition
GO:0010862  positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0032436  positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0001934  positive regulation of protein amino acid phosphorylation
GO:0001921  positive regulation of receptor recycling
GO:0032968  positive regulation of RNA elongation from RNA polymerase II promoter
GO:0060391  positive regulation of SMAD protein nuclear translocation
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0030511  positive regulation of transforming growth factor beta receptor signaling pathway
GO:0015031  protein transport
GO:0006898  receptor-mediated endocytosis
GO:0016055  Wnt receptor signaling pathway

Cellular Component

GO:0016324  apical plasma membrane
GO:0030132  clathrin coat of coated pit
GO:0030665  clathrin coated vesicle membrane
GO:0005905  coated pit
GO:0005765  lysosomal membrane
GO:0005634  nucleus
GO:0005886  plasma membrane
GO:0070022  transforming growth factor beta receptor complex

Molecular Function

GO:0005178  integrin binding
GO:0005546  phosphatidylinositol-4,5-bisphosphate binding
GO:0005515  protein binding
GO:0008022  protein C-terminus binding
GO:0046332  SMAD binding