angiotensin II receptor, type 1

詳細情報を見る

同義遺伝子名

AT2R1A, AT2R1B, AT2R1, AGTR1, AT1AR, angiotensin II receptor, type 1, AT1B, type 1A angiotensin II (Ang II) receptor (AT1A), angiotensin receptor 1B, AGTR1B, AT1a receptor, AT1BR, AT1A receptor, AGTR1A, AG2S, HAT1R, type 1 Ang II receptor (AT1), Type-1 angiotensin II receptor

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:7.10 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:30.70 脊柱:112.30 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:18.90 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
GeneChip 大脳:3.86 小脳:3.81 脳幹:5.23 脳梁:3.84 松果体:- 末梢神経:4.77 脊柱:4.07 網膜:- 目:- 動脈:5.93 静脈:6.21 リンパ節:4.84 末梢血:- 脾臓:6.42 胸腺:5.02 骨髄:4.28 脂肪:7.55 骨:- 皮膚:6.74
CAGE nodata
RNA-seq 大脳:0.00 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:0.74 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:0.18 骨:- 皮膚:-
EST 子宮:- 胎盤:160.30 前立腺:- 卵巣:- 精巣:8.70 心臓:38.30 骨格筋:20.10 食道:- 胃:- 腸:- 結腸:8.50     肝臓:73.90        肺:9.80    膀胱:- 腎臓:72.80 下垂体:- 甲状腺:- 副腎:50.80 膵臓:- 乳腺:74.30 唾液腺:-
GeneChip 子宮:5.03 胎盤:9.26 前立腺:6.65 卵巣:4.61 精巣:4.50 心臓:6.23 骨格筋:6.29 食道:4.66 胃:5.55 腸:5.06 結腸:5.90 肝臓:8.31 肺:6.04 膀胱:- 腎臓:6.38 下垂体:4.65 甲状腺:5.79 副腎:8.54 膵臓:4.64 乳腺:6.75 唾液腺:4.67
CAGE nodata
RNA-seq 子宮:- 胎盤:- 前立腺:0.00 卵巣:0.00 精巣:0.00 心臓:0.08 骨格筋:0.00 食道:- 胃:- 腸:- 結腸:0.00     肝臓:0.20        肺:0.00    膀胱:- 腎臓:0.00 下垂体:- 甲状腺:0.08 副腎:0.07 膵臓:- 乳腺:0.00 唾液腺:-

IDs

Refseq ID NM_004835
Gene ID 185
Unigene ID Hs.477887
Probe set ID 205357_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000144891
GTEx ID ENSG00000144891

オーソログ対応遺伝子

マウス[3]  NM_177322, NM_175086
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

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遺伝子オントロジー  (GO ID)

Biological Process

GO:0007200  activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger
GO:0019722  calcium-mediated signaling
GO:0060326  cell chemotaxis
GO:0007204  elevation of cytosolic calcium ion concentration
GO:0051482  elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)
GO:0007186  G-protein coupled receptor protein signaling pathway
GO:0001822  kidney development
GO:0034374  low-density lipoprotein particle remodeling
GO:0032270  positive regulation of cellular protein metabolic process
GO:0010873  positive regulation of cholesterol esterification
GO:0050729  positive regulation of inflammatory response
GO:0010744  positive regulation of macrophage derived foam cell differentiation
GO:0033864  positive regulation of NAD(P)H oxidase activity
GO:0032430  positive regulation of phospholipase A2 activity
GO:0002034  regulation of blood vessel size by renin-angiotensin
GO:0001558  regulation of cell growth
GO:0042127  regulation of cell proliferation
GO:0050727  regulation of inflammatory response
GO:0003081  regulation of systemic arterial blood pressure by renin-angiotensin
GO:0019229  regulation of vasoconstriction
GO:0042312  regulation of vasodilation
GO:0002018  renin-angiotensin regulation of aldosterone production
GO:0007266  Rho protein signal transduction

Cellular Component

GO:0016021  integral to membrane
GO:0005887  integral to plasma membrane
GO:0005886  plasma membrane

Molecular Function

GO:0010698  acetyltransferase activator activity
GO:0001596  angiotensin type I receptor activity
GO:0004945  angiotensin type II receptor activity
GO:0031711  bradykinin receptor binding
GO:0005515  protein binding
GO:0046982  protein heterodimerization activity