ATP-binding cassette, sub-family A (ABC1), member 1

 詳細情報を見る

同義遺伝子名

Tangier disease, ABCA1, HDLDT1, ATP-binding cassette 1, ABC1, TGD, ATP-binding cassette transporter A1, ATP-binding cassette sub-family A member 1, CERP, Cholesterol efflux regulatory protein, ABC-1, ATP-binding cassette transporter 1, FLJ14958

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST nodata
GeneChip 大脳:5.18 小脳:3.91 脳幹:5.40 脳梁:5.81 松果体:- 末梢神経:6.21 脊柱:6.34 網膜:- 目:- 動脈:5.24 静脈:5.45 リンパ節:5.64 末梢血:- 脾臓:5.25 胸腺:6.86 骨髄:5.17 脂肪:6.54 骨:- 皮膚:6.18
CAGE 大脳:3.09 小脳:- 脳幹:3.49 脳梁:3.55 松果体:2.83 末梢神経:- 脊柱:4.29 網膜:- 目:- 動脈:4.17 静脈:3.82 リンパ節:3.89 末梢血:- 脾臓:3.94 胸腺:4.02 骨髄:- 脂肪:4.63 骨:- 皮膚:-
RNA-seq 大脳:1.63 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:2.75 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:4.33 骨:- 皮膚:-
殖 筋 消 肝 肺 腎 泌
EST nodata
GeneChip 子宮:5.61 胎盤:7.50 前立腺:5.24 卵巣:5.92 精巣:4.81 心臓:5.87 骨格筋:5.84 食道:5.19 胃:5.67 腸:5.40 結腸:5.20 肝臓:7.16 肺:6.60 膀胱:- 腎臓:5.12 下垂体:4.41 甲状腺:5.38 副腎:7.73 膵臓:5.19 乳腺:5.82 唾液腺:4.27
CAGE 子宮:3.61 胎盤:4.04 前立腺:3.72 卵巣:3.51 精巣:3.53 心臓:3.83 骨格筋:4.17 食道:3.41 胃:- 腸:3.48 結腸:4.11     肝臓:4.66    肺:4.12 膀胱:4.19 腎臓:2.60 下垂体:2.34 甲状腺:3.05 副腎:- 膵臓:2.98 乳腺:4.49 唾液腺:2.53
RNA-seq 子宮:- 胎盤:- 前立腺:3.38 卵巣:2.62 精巣:2.20 心臓:1.37 骨格筋:2.69 食道:- 胃:- 腸:- 結腸:3.14     肝臓:4.64        肺:2.95    膀胱:- 腎臓:1.81 下垂体:- 甲状腺:3.19 副腎:3.07 膵臓:- 乳腺:3.62 唾液腺:-

詳細情報

IDs

Refseq ID NM_005502
Gene ID 19
Unigene ID -
Probe set ID 203504_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000165029
GTEx ID ENSG00000165029

オーソログ対応遺伝子

マウス[3]  NM_013454
ラット [0]  

染色体

9q31.1  [107,543,283  -  107,690,518]

遺伝子ファミリー (Interpro ID)

IPR003439  ABC transporter-like
IPR003593  ATPase, AAA+ type, core

Link to Pubmed  (Pubmed ID)

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遺伝子オントロジー  (GO ID)

Biological Process

GO:0044255  cellular lipid metabolic process
GO:0071222  cellular response to lipopolysaccharide
GO:0071300  cellular response to retinoic acid
GO:0033344  cholesterol efflux
GO:0042632  cholesterol homeostasis
GO:0008203  cholesterol metabolic process
GO:0016197  endosome transport
GO:0007186  G-protein coupled receptor protein signaling pathway
GO:0034380  high-density lipoprotein particle assembly
GO:0050702  interleukin-1 beta secretion
GO:0032367  intracellular cholesterol transport
GO:0042157  lipoprotein metabolic process
GO:0007040  lysosome organization
GO:0010887  negative regulation of cholesterol storage
GO:0010745  negative regulation of macrophage derived foam cell differentiation
GO:0002790  peptide secretion
GO:0006911  phagocytosis, engulfment
GO:0033700  phospholipid efflux
GO:0055091  phospholipid homeostasis
GO:0045332  phospholipid translocation
GO:0060155  platelet dense granule organization
GO:0030819  positive regulation of cAMP biosynthetic process
GO:0010875  positive regulation of cholesterol efflux
GO:0006497  protein amino acid lipidation
GO:0032489  regulation of Cdc42 protein signal transduction
GO:0034616  response to laminar fluid shear stress
GO:0055098  response to low-density lipoprotein stimulus
GO:0043691  reverse cholesterol transport

Cellular Component

GO:0030139  endocytic vesicle
GO:0005794  Golgi apparatus
GO:0005887  integral to plasma membrane
GO:0045121  membrane raft
GO:0045335  phagocytic vesicle
GO:0005886  plasma membrane

Molecular Function

GO:0008509  anion transmembrane transporter activity
GO:0034186  apolipoprotein A-I binding
GO:0034188  apolipoprotein A-I receptor activity
GO:0034185  apolipoprotein binding
GO:0005524  ATP binding
GO:0016887  ATPase activity
GO:0015485  cholesterol binding
GO:0017127  cholesterol transporter activity
GO:0005543  phospholipid binding
GO:0005548  phospholipid transporter activity
GO:0005515  protein binding
GO:0031267  small GTPase binding
GO:0019905  syntaxin binding