endothelin 1

詳細情報を見る

同義遺伝子名

Preproendothelin-1, PPET1, Endothelin-1 precursor, ET1, EDN1, endothelin 1

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:26.10 小脳:- 脳幹:- 脳梁:29.20 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:29.40 動脈:329.70 静脈:533.20 リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:80.70 骨:12.80 皮膚:24
GeneChip 大脳:5.75 小脳:4.90 脳幹:5.80 脳梁:5.37 松果体:- 末梢神経:5.72 脊柱:5.38 網膜:- 目:- 動脈:6.48 静脈:6.35 リンパ節:5.26 末梢血:- 脾臓:5.99 胸腺:4.91 骨髄:5.15 脂肪:6.32 骨:- 皮膚:6.31
CAGE 大脳:2.89 小脳:- 脳幹:2.62 脳梁:2.26 松果体:3.43 末梢神経:- 脊柱:3.03 網膜:- 目:- 動脈:3.00 静脈:2.27 リンパ節:2.12 末梢血:- 脾臓:2.29 胸腺:0.61 骨髄:- 脂肪:4.26 骨:- 皮膚:-
RNA-seq 大脳:1.60 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:1.34 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:0.00 骨:- 皮膚:-
EST 子宮:18.20 胎盤:51 前立腺:- 卵巣:223.60 精巣:8.70 心臓:51.10 骨格筋:- 食道:- 胃:21.20 腸:- 結腸:-     肝臓:31.70        肺:78.20    膀胱:- 腎臓:41.60 下垂体:- 甲状腺:- 副腎:- 膵臓:8.90 乳腺:- 唾液腺:-
GeneChip 子宮:5.98 胎盤:5.98 前立腺:5.79 卵巣:5.85 精巣:5.58 心臓:5.65 骨格筋:5.26 食道:5.53 胃:5.99 腸:5.91 結腸:5.94 肝臓:5.20 肺:7.31 膀胱:- 腎臓:5.62 下垂体:5.12 甲状腺:4.96 副腎:5.24 膵臓:6.04 乳腺:6.46 唾液腺:5.76
CAGE 子宮:2.81 胎盤:2.97 前立腺:2.51 卵巣:2.25 精巣:1.90 心臓:2.39 骨格筋:3.85 食道:2.60 胃:- 腸:2.13 結腸:1.56     肝臓:0.71    肺:3.89 膀胱:2.42 腎臓:2.31 下垂体:1.09 甲状腺:1.90 副腎:- 膵臓:1.74 乳腺:3.64 唾液腺:1.49
RNA-seq 子宮:- 胎盤:- 前立腺:1.69 卵巣:0.00 精巣:0.64 心臓:1.40 骨格筋:0.99 食道:- 胃:- 腸:- 結腸:0.13     肝臓:0.33        肺:1.98    膀胱:- 腎臓:0.00 下垂体:- 甲状腺:0.00 副腎:0.00 膵臓:- 乳腺:0.67 唾液腺:-

IDs

Refseq ID NM_001168319
Gene ID 1906
Unigene ID Hs.511899
Probe set ID 218995_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000078401
GTEx ID ENSG00000078401

オーソログ対応遺伝子

マウス[1]  NM_010104
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

1280264
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遺伝子オントロジー  (GO ID)

Biological Process

GO:0031583  activation of phospholipase D activity by G-protein coupled receptor protein signaling pathway
GO:0007205  activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway
GO:0014824  artery smooth muscle contraction
GO:0007589  body fluid secretion
GO:0019722  calcium-mediated signaling
GO:0051216  cartilage development
GO:0016049  cell growth
GO:0007166  cell surface receptor linked signal transduction
GO:0007267  cell-cell signaling
GO:0071347  cellular response to interleukin-1
GO:0071356  cellular response to tumor necrosis factor
GO:0009953  dorsal/ventral pattern formation
GO:0007204  elevation of cytosolic calcium ion concentration
GO:0051482  elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)
GO:0042045  epithelial fluid transport
GO:0007186  G-protein coupled receptor protein signaling pathway
GO:0015758  glucose transport
GO:0007507  heart development
GO:0001821  histamine secretion
GO:0001701  in utero embryonic development
GO:0048016  inositol phosphate-mediated signaling
GO:0045321  leukocyte activation
GO:0060137  maternal process involved in parturition
GO:0051899  membrane depolarization
GO:0042474  middle ear morphogenesis
GO:0010259  multicellular organismal aging
GO:0030195  negative regulation of blood coagulation
GO:0030818  negative regulation of cAMP biosynthetic process
GO:0032269  negative regulation of cellular protein metabolic process
GO:0046888  negative regulation of hormone secretion
GO:0051771  negative regulation of nitric-oxide synthase biosynthetic process
GO:0034392  negative regulation of smooth muscle cell apoptosis
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0014032  neural crest cell development
GO:0030593  neutrophil chemotaxis
GO:0030185  nitric oxide transport
GO:0001569  patterning of blood vessels
GO:0030072  peptide hormone secretion
GO:0014065  phosphoinositide 3-kinase cascade
GO:0010613  positive regulation of cardiac muscle hypertrophy
GO:0030335  positive regulation of cell migration
GO:0008284  positive regulation of cell proliferation
GO:0045793  positive regulation of cell size
GO:0070101  positive regulation of chemokine-mediated signaling pathway
GO:0010595  positive regulation of endothelial cell migration
GO:0010460  positive regulation of heart rate
GO:0046887  positive regulation of hormone secretion
GO:0043507  positive regulation of JUN kinase activity
GO:0043406  positive regulation of MAP kinase activity
GO:0045840  positive regulation of mitosis
GO:0090023  positive regulation of neutrophil chemotaxis
GO:0045429  positive regulation of nitric oxide biosynthetic process
GO:0042482  positive regulation of odontogenesis
GO:0060585  positive regulation of prostaglandin-endoperoxidase synthase activity
GO:0010870  positive regulation of receptor biosynthetic process
GO:0060298  positive regulation of sarcomere organization
GO:0048661  positive regulation of smooth muscle cell proliferation
GO:0045987  positive regulation of smooth muscle contraction
GO:0001516  prostaglandin biosynthetic process
GO:0042313  protein kinase C deactivation
GO:0007243  protein kinase cascade
GO:0006885  regulation of pH
GO:0051930  regulation of sensory perception of pain
GO:0003100  regulation of systemic arterial blood pressure by endothelin
GO:0019229  regulation of vasoconstriction
GO:0007585  respiratory gaseous exchange
GO:0043200  response to amino acid stimulus
GO:0001666  response to hypoxia
GO:0032496  response to lipopolysaccharide
GO:0035094  response to nicotine
GO:0033574  response to testosterone stimulus
GO:0043179  rhythmic excitation
GO:0019233  sensory perception of pain
GO:0042554  superoxide anion generation
GO:0042310  vasoconstriction
GO:0014826  vein smooth muscle contraction

Cellular Component

GO:0005737  cytoplasm
GO:0005576  extracellular region
GO:0005615  extracellular space

Molecular Function

GO:0005125  cytokine activity
GO:0031707  endothelin A receptor binding
GO:0031708  endothelin B receptor binding
GO:0005179  hormone activity
GO:0005515  protein binding