endothelin receptor type A

詳細情報を見る

同義遺伝子名

hET-AR, EDNRA, Endothelin-1 receptor precursor, ETRA, endothelin receptor type A, ETA, ET-A, Endothelin A receptor, ETA-R

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:33.20 小脳:37.80 脳幹:- 脳梁:87.50 松果体:- 末梢神経:92 脊柱:112.30 網膜:- 目:41.10 動脈:89.90 静脈:- リンパ節:- 末梢血:- 脾臓:132.30 胸腺:38.70 骨髄:- 脂肪:80.70 骨:51.20 皮膚:33.60
GeneChip 大脳:3.46 小脳:3.14 脳幹:3.56 脳梁:3.29 松果体:- 末梢神経:5.46 脊柱:3.46 網膜:- 目:- 動脈:5.41 静脈:6.73 リンパ節:4.48 末梢血:- 脾臓:5.57 胸腺:4.28 骨髄:3.24 脂肪:5.20 骨:- 皮膚:4.26
CAGE 大脳:1.56 小脳:- 脳幹:1.82 脳梁:1.49 松果体:1.65 末梢神経:- 脊柱:1.84 網膜:- 目:- 動脈:3.14 静脈:2.87 リンパ節:2.01 末梢血:- 脾臓:3.38 胸腺:2.00 骨髄:- 脂肪:2.93 骨:- 皮膚:-
RNA-seq 大脳:0.40 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:0.59 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:0.73 骨:- 皮膚:-
EST 子宮:419.20 胎盤:65.60 前立腺:112.60 卵巣:37.30 精巣:77.90 心臓:102.20 骨格筋:- 食道:- 胃:42.50 腸:- 結腸:8.50     肝臓:21.10        肺:102.60    膀胱:125.60 腎臓:- 下垂体:347.90 甲状腺:- 副腎:- 膵臓:- 乳腺:65.10 唾液腺:-
GeneChip 子宮:8.60 胎盤:4.60 前立腺:7.62 卵巣:6.87 精巣:4.68 心臓:6.29 骨格筋:3.75 食道:4.17 胃:5.06 腸:4.68 結腸:4.04 肝臓:3.69 肺:7.36 膀胱:- 腎臓:4.05 下垂体:3.59 甲状腺:4.58 副腎:4.93 膵臓:3.42 乳腺:5.81 唾液腺:3.83
CAGE 子宮:4.86 胎盤:2.69 前立腺:4.07 卵巣:4.09 精巣:3.09 心臓:3.35 骨格筋:2.40 食道:2.60 胃:- 腸:1.81 結腸:2.10     肝臓:1.25    肺:3.63 膀胱:3.63 腎臓:2.06 下垂体:1.53 甲状腺:2.24 副腎:- 膵臓:0 乳腺:3.02 唾液腺:2.06
RNA-seq 子宮:- 胎盤:- 前立腺:0.75 卵巣:2.53 精巣:1.87 心臓:0.45 骨格筋:0.24 食道:- 胃:- 腸:- 結腸:0.69     肝臓:0.00        肺:1.08    膀胱:- 腎臓:0.18 下垂体:- 甲状腺:0.54 副腎:2.04 膵臓:- 乳腺:1.21 唾液腺:-

IDs

Refseq ID NM_001166055
Gene ID 1909
Unigene ID Hs.183713
Probe set ID 204463_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000151617
GTEx ID ENSG00000151617

オーソログ対応遺伝子

マウス[4]  NM_010332
ラット[2]  NM_012550

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

遺伝子オントロジー  (GO ID)

Biological Process

GO:0007190  activation of adenylate cyclase activity
GO:0007202  activation of phospholipase C activity
GO:0007205  activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway
GO:0007568  aging
GO:0014824  artery smooth muscle contraction
GO:0008283  cell proliferation
GO:0071260  cellular response to mechanical stimulus
GO:0007204  elevation of cytosolic calcium ion concentration
GO:0051482  elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)
GO:0048484  enteric nervous system development
GO:0048144  fibroblast proliferation
GO:0007186  G-protein coupled receptor protein signaling pathway
GO:0003094  glomerular filtration
GO:0015758  glucose transport
GO:0060322  head development
GO:0007507  heart development
GO:0001821  histamine secretion
GO:0001701  in utero embryonic development
GO:0060137  maternal process involved in parturition
GO:0043066  negative regulation of apoptosis
GO:0030818  negative regulation of cAMP biosynthetic process
GO:0014032  neural crest cell development
GO:0001569  patterning of blood vessels
GO:0043084  penile erection
GO:0008284  positive regulation of cell proliferation
GO:0070374  positive regulation of ERK1 and ERK2 cascade
GO:0050729  positive regulation of inflammatory response
GO:0090184  positive regulation of kidney development
GO:0090023  positive regulation of neutrophil chemotaxis
GO:0042482  positive regulation of odontogenesis
GO:0001934  positive regulation of protein amino acid phosphorylation
GO:0051281  positive regulation of release of sequestered calcium ion into cytosol
GO:0008217  regulation of blood pressure
GO:0050678  regulation of epithelial cell proliferation
GO:0007585  respiratory gaseous exchange
GO:0001666  response to hypoxia
GO:0032496  response to lipopolysaccharide
GO:0043278  response to morphine
GO:0007266  Rho protein signal transduction
GO:0019233  sensory perception of pain
GO:0007165  signal transduction
GO:0048659  smooth muscle cell proliferation
GO:0006939  smooth muscle contraction
GO:0042310  vasoconstriction

Cellular Component

GO:0005887  integral to plasma membrane
GO:0016020  membrane
GO:0031965  nuclear membrane
GO:0005886  plasma membrane
GO:0030315  T-tubule

Molecular Function

GO:0004962  endothelin receptor activity
GO:0004435  phosphoinositide phospholipase C activity
GO:0005515  protein binding