v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)

同義遺伝子名

p180erbB4, HER4, Tyrosine kinase-type cell surface receptor HER4, Receptor tyrosine-protein kinase erbB-4 precursor, MGC138404, ERBB4

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:52.10

小脳:25.20

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:23.50

動脈:-

静脈:-

リンパ節:-

末梢血:18.20

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:38.40

皮膚:19.20

GeneChip

大脳:7.42

小脳:7.03

脳幹:7.37

脳梁:7.07

松果体:-

末梢神経:5.26

脊柱:7.08

網膜:-

目:-

動脈:5.82

静脈:5.74

リンパ節:4.40

末梢血:-

脾臓:4.71

胸腺:4.14

骨髄:4.67

脂肪:4.41

骨:-

皮膚:4.28

CAGE

大脳:3.93

小脳:-

脳幹:3.65

脳梁:3.56

松果体:4.91

末梢神経:-

脊柱:3.52

網膜:-

目:-

動脈:3.54

静脈:1.44

リンパ節:0.71

末梢血:-

脾臓:0.45

胸腺:0

骨髄:-

脂肪:1.41

骨:-

皮膚:-

RNA-seq

大脳:0.07

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:0.00

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:0.06

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:-

胎盤:7.30

前立腺:11.30

卵巣:260.80

精巣:73.50

心臓:38.30

骨格筋:20.10

食道:-

胃:-

腸:-

結腸:8.50

肝臓:21.10

肺:29.30

膀胱:-

腎臓:124.80

下垂体:116

甲状腺:163.70

副腎:-

膵臓:-

乳腺:130.10

唾液腺:-

GeneChip

子宮:4.35

胎盤:4.56

前立腺:4.39

卵巣:6.32

精巣:6.33

心臓:5.79

骨格筋:6.16

食道:4.40

胃:4.43

腸:4.58

結腸:4.15

肝臓:4.99

肺:4.89

膀胱:-

腎臓:7.28

下垂体:6.52

甲状腺:6.32

副腎:4.67

膵臓:5.53

乳腺:6.32

唾液腺:7.80

CAGE

子宮:1.63

胎盤:0.43

前立腺:1.32

卵巣:1.94

精巣:3.51

心臓:2.42

骨格筋:1.09

食道:0.52

胃:-

腸:0.33

結腸:0.71

肝臓:0

肺:2.19

膀胱:1.06

腎臓:3.45

下垂体:3.01

甲状腺:2.53

副腎:-

膵臓:2.08

乳腺:2.19

唾液腺:4.06

RNA-seq

子宮:-

胎盤:-

前立腺:0.00

卵巣:0.61

精巣:0.76

心臓:1.07

骨格筋:0.00

食道:-

胃:-

腸:-

結腸:0.00

肝臓:0.00

肺:0.00

膀胱:-

腎臓:0.25

下垂体:-

甲状腺:0.37

副腎:0.00

膵臓:-

乳腺:0.00

唾液腺:-

IDs

Refseq ID	NM_005235
Gene ID	2066
Unigene ID	Hs.390729
Probe set ID	214053_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000178568
GTEx ID	ENSG00000178568

オーソログ対応遺伝子

マウス[1]	NM_010154
ラット [0]

染色体

2q34 [212,240,446 - 213,403,565]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR016245	Tyrosine protein kinase, EGF/ERB/XmrK receptor
IPR020685	Tyrosine-protein kinase
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020933	Tyrosine-protein kinase, fibroblast growth factor receptor, conserved region
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

遺伝子オントロジー (GO ID)

Biological Process

GO:0045165	cell fate commitment
GO:0016477	cell migration
GO:0008283	cell proliferation
GO:0021551	central nervous system morphogenesis
GO:0009880	embryonic pattern specification
GO:0007173	epidermal growth factor receptor signaling pathway
GO:0008543	fibroblast growth factor receptor signaling pathway
GO:0007507	heart development
GO:0045087	innate immune response
GO:0007595	lactation
GO:0060749	mammary gland alveolus development
GO:0060644	mammary gland epithelial cell differentiation
GO:0043653	mitochondrial fragmentation during apoptosis
GO:0043066	negative regulation of apoptosis
GO:0008285	negative regulation of cell proliferation
GO:0048011	nerve growth factor receptor signaling pathway
GO:0007399	nervous system development
GO:0001755	neural crest cell migration
GO:0021889	olfactory bulb interneuron differentiation
GO:0018108	peptidyl-tyrosine phosphorylation
GO:0048015	phosphoinositide-mediated signaling
GO:0060045	positive regulation of cardiac muscle cell proliferation
GO:0008284	positive regulation of cell proliferation
GO:0070374	positive regulation of ERK1 and ERK2 cascade
GO:0043552	positive regulation of phosphoinositide 3-kinase activity
GO:0001934	positive regulation of protein amino acid phosphorylation
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0042523	positive regulation of tyrosine phosphorylation of Stat5 protein
GO:0046777	protein amino acid autophosphorylation
GO:0030334	regulation of cell migration
GO:0007165	signal transduction
GO:0006351	transcription, DNA-dependent
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway

Cellular Component

GO:0016323	basolateral plasma membrane
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005576	extracellular region
GO:0016021	integral to membrane
GO:0005759	mitochondrial matrix
GO:0005739	mitochondrion
GO:0005730	nucleolus
GO:0005654	nucleoplasm
GO:0005634	nucleus
GO:0005886	plasma membrane

Molecular Function

GO:0005524	ATP binding
GO:0044212	DNA regulatory region binding
GO:0005154	epidermal growth factor receptor binding
GO:0005515	protein binding
GO:0042803	protein homodimerization activity
GO:0004713	protein tyrosine kinase activity
GO:0004716	receptor signaling protein tyrosine kinase activity
GO:0004714	transmembrane receptor protein tyrosine kinase activity

v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function