v-akt murine thymoma viral oncogene homolog 1

詳細情報を見る

同義遺伝子名

v-akt murine thymoma viral oncogene homolog 1, Protein kinase B, AKT1, RAC, Akt-1, PRKBA, MGC99656, RAC-alpha serine/threonine-protein kinase, RAC-ALPHA, Akt 1, RAC-PK-alpha, AKT 1, C-AKT, PKB, AKT-1

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:64 小脳:37.80 脳幹:- 脳梁:- 松果体:- 末梢神経:61.30 脊柱:- 網膜:- 目:223.30 動脈:60 静脈:66.60 リンパ節:131.40 末梢血:72.90 脾臓:18.90 胸腺:38.70 骨髄:59 脂肪:121 骨:51.20 皮膚:86.40
GeneChip 大脳:7.09 小脳:7.12 脳幹:6.99 脳梁:7.06 松果体:- 末梢神経:7.18 脊柱:7.13 網膜:- 目:- 動脈:7.70 静脈:7.60 リンパ節:7.58 末梢血:- 脾臓:8.02 胸腺:7.65 骨髄:7.10 脂肪:7.85 骨:- 皮膚:7.43
CAGE 大脳:2.90 小脳:- 脳幹:3.02 脳梁:3.14 松果体:2.50 末梢神経:- 脊柱:2.73 網膜:- 目:- 動脈:3.96 静脈:3.35 リンパ節:3.30 末梢血:- 脾臓:3.64 胸腺:3.24 骨髄:- 脂肪:3.55 骨:- 皮膚:-
RNA-seq 大脳:4.06 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:4.94 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:5.56 骨:- 皮膚:-
EST 子宮:100.20 胎盤:76.50 前立腺:112.60 卵巣:- 精巣:47.60 心臓:166 骨格筋:80.40 食道:- 胃:42.50 腸:- 結腸:93.30     肝臓:31.70        肺:107.50    膀胱:- 腎臓:41.60 下垂体:- 甲状腺:- 副腎:101.60 膵臓:80 乳腺:232.30 唾液腺:-
GeneChip 子宮:7.54 胎盤:7.37 前立腺:8.14 卵巣:7.44 精巣:7.06 心臓:7.54 骨格筋:7 食道:7.72 胃:7.87 腸:7.76 結腸:7.94 肝臓:7.89 肺:7.84 膀胱:- 腎臓:7.50 下垂体:7 甲状腺:7.96 副腎:7.87 膵臓:7.33 乳腺:7.96 唾液腺:7.86
CAGE 子宮:3.31 胎盤:3.37 前立腺:3.60 卵巣:3.33 精巣:2.98 心臓:3.62 骨格筋:3.17 食道:3.58 胃:- 腸:3.27 結腸:3.62     肝臓:3.72    肺:3.48 膀胱:3.72 腎臓:3.33 下垂体:2.43 甲状腺:3.46 副腎:- 膵臓:3.57 乳腺:3.69 唾液腺:3.52
RNA-seq 子宮:- 胎盤:- 前立腺:5.17 卵巣:5.30 精巣:4.83 心臓:4.84 骨格筋:4.32 食道:- 胃:- 腸:- 結腸:5.18     肝臓:4.80        肺:5.16    膀胱:- 腎臓:4.79 下垂体:- 甲状腺:5.11 副腎:5.43 膵臓:- 乳腺:5.54 唾液腺:-

IDs

Refseq ID NM_001014431
Gene ID 207
Unigene ID Hs.525622
Probe set ID 207163_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000142208
GTEx ID ENSG00000142208

オーソログ対応遺伝子

マウス[4]  NM_001165894, NM_009652
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

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遺伝子オントロジー  (GO ID)

Biological Process

GO:0006924  activation-induced cell death of T cells
GO:0007568  aging
GO:0042640  anagen
GO:0006915  apoptosis
GO:0008637  apoptotic mitochondrial changes
GO:0007596  blood coagulation
GO:0030154  cell differentiation
GO:0030030  cell projection organization
GO:0008283  cell proliferation
GO:0071364  cellular response to epidermal growth factor stimulus
GO:0071456  cellular response to hypoxia
GO:0032869  cellular response to insulin stimulus
GO:0031018  endocrine pancreas development
GO:0007173  epidermal growth factor receptor signaling pathway
GO:0008543  fibroblast growth factor receptor signaling pathway
GO:0007186  G-protein coupled receptor protein signaling pathway
GO:0010467  gene expression
GO:0007281  germ cell development
GO:0042593  glucose homeostasis
GO:0006006  glucose metabolic process
GO:0015758  glucose transport
GO:0005978  glycogen biosynthetic process
GO:0060709  glycogen cell development involved in embryonic placenta development
GO:0006954  inflammatory response
GO:0045087  innate immune response
GO:0008286  insulin receptor signaling pathway
GO:0048009  insulin-like growth factor receptor signaling pathway
GO:0060716  labyrinthine layer blood vessel development
GO:0060644  mammary gland epithelial cell differentiation
GO:0001893  maternal placenta development
GO:0016044  membrane organization
GO:0016071  mRNA metabolic process
GO:0032287  myelin maintenance in the peripheral nervous system
GO:0043066  negative regulation of apoptosis
GO:0010507  negative regulation of autophagy
GO:0043154  negative regulation of caspase activity
GO:0045792  negative regulation of cell size
GO:0010951  negative regulation of endopeptidase activity
GO:0031999  negative regulation of fatty acid beta-oxidation
GO:0046329  negative regulation of JNK cascade
GO:0010748  negative regulation of plasma membrane long-chain fatty acid transport
GO:0006469  negative regulation of protein kinase activity
GO:0045861  negative regulation of proteolysis
GO:0090201  negative regulation of release of cytochrome c from mitochondria
GO:0048011  nerve growth factor receptor signaling pathway
GO:0006809  nitric oxide biosynthetic process
GO:0046209  nitric oxide metabolic process
GO:0001649  osteoblast differentiation
GO:0018105  peptidyl-serine phosphorylation
GO:0048015  phosphoinositide-mediated signaling
GO:0016310  phosphorylation
GO:0030168  platelet activation
GO:0043065  positive regulation of apoptosis
GO:0043536  positive regulation of blood vessel endothelial cell migration
GO:0030307  positive regulation of cell growth
GO:0032270  positive regulation of cellular protein metabolic process
GO:0031659  positive regulation of cyclin-dependent protein kinase activity during G1/S
GO:0090004  positive regulation of establishment of protein localization in plasma membrane
GO:0045600  positive regulation of fat cell differentiation
GO:0046326  positive regulation of glucose import
GO:0010907  positive regulation of glucose metabolic process
GO:0045725  positive regulation of glycogen biosynthetic process
GO:0046889  positive regulation of lipid biosynthetic process
GO:0045429  positive regulation of nitric oxide biosynthetic process
GO:0051000  positive regulation of nitric-oxide synthase activity
GO:0033138  positive regulation of peptidyl-serine phosphorylation
GO:0032436  positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0001934  positive regulation of protein amino acid phosphorylation
GO:0010765  positive regulation of sodium ion transport
GO:0051091  positive regulation of transcription factor activity
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045907  positive regulation of vasoconstriction
GO:0046777  protein amino acid autophosphorylation
GO:0006468  protein amino acid phosphorylation
GO:0030163  protein catabolic process
GO:0000060  protein import into nucleus, translocation
GO:0043491  protein kinase B signaling cascade
GO:0006464  protein modification process
GO:0016567  protein ubiquitination
GO:0030334  regulation of cell migration
GO:0005979  regulation of glycogen biosynthetic process
GO:0010975  regulation of neuron projection development
GO:0050999  regulation of nitric-oxide synthase activity
GO:0006417  regulation of translation
GO:0034405  response to fluid shear stress
GO:0032094  response to food
GO:0009408  response to heat
GO:0070141  response to UV-A
GO:0016070  RNA metabolic process
GO:0007165  signal transduction
GO:0051146  striated muscle cell differentiation
GO:0031295  T cell costimulation
GO:0006412  translation

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0030027  lamellipodium
GO:0015630  microtubule cytoskeleton
GO:0005654  nucleoplasm
GO:0005634  nucleus
GO:0005886  plasma membrane
GO:0005819  spindle

Molecular Function

GO:0005524  ATP binding
GO:0019899  enzyme binding
GO:0042802  identical protein binding
GO:0016301  kinase activity
GO:0030235  nitric-oxide synthase regulator activity
GO:0005547  phosphatidylinositol-3,4,5-trisphosphate binding
GO:0043325  phosphatidylinositol-3,4-bisphosphate binding
GO:0005515  protein binding
GO:0004672  protein kinase activity
GO:0005080  protein kinase C binding
GO:0004674  protein serine/threonine kinase activity