coagulation factor II (thrombin) receptor-like 1

同義遺伝子名

proteinase-activated receptor 2 (PAR2), GPR11, Coagulation factor II receptor-like 1, F2RL1, Proteinase-activated receptor 2 precursor, Thrombin receptor-like 1, G-protein coupled receptor 11, coagulation factor II (thrombin) receptor-like 1, proteinase-activated receptor 2 (PAR-2), PAR-2

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:4.70

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:30

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

GeneChip

大脳:5.11

小脳:5.09

脳幹:5.13

脳梁:4.97

松果体:-

末梢神経:5.10

脊柱:5.08

網膜:-

目:-

動脈:5.14

静脈:5.25

リンパ節:4.95

末梢血:-

脾臓:4.90

胸腺:4.81

骨髄:5.10

脂肪:5.22

骨:-

皮膚:5.75

CAGE

大脳:0.47

小脳:-

脳幹:0.21

脳梁:0.82

松果体:0.51

末梢神経:-

脊柱:0.90

網膜:-

目:-

動脈:1.43

静脈:0.34

リンパ節:1.68

末梢血:-

脾臓:1.71

胸腺:0.33

骨髄:-

脂肪:0.26

骨:-

皮膚:-

RNA-seq

大脳:0.62

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:1.39

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:0.39

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:-

胎盤:3.60

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:-

食道:-

胃:-

腸:-

結腸:50.90

肝臓:-

肺:4.90

膀胱:-

腎臓:41.60

下垂体:232

甲状腺:-

副腎:50.80

膵臓:35.60

乳腺:27.90

唾液腺:-

GeneChip

子宮:4.94

胎盤:5.60

前立腺:5.07

卵巣:5.03

精巣:4.84

心臓:5.28

骨格筋:5.33

食道:5.43

胃:5.26

腸:5.70

結腸:6.49

肝臓:5.12

肺:4.90

膀胱:-

腎臓:5.49

下垂体:5.21

甲状腺:5.09

副腎:5.09

膵臓:5.81

乳腺:5.01

唾液腺:5.41

CAGE

子宮:1.10

胎盤:1.47

前立腺:2.27

卵巣:0.86

精巣:0.41

心臓:1.17

骨格筋:0

食道:2.15

胃:-

腸:4.47

結腸:3.92

肝臓:2.22

肺:1.66

膀胱:1.99

腎臓:3.67

下垂体:1.69

甲状腺:2.60

副腎:-

膵臓:3.06

乳腺:1.36

唾液腺:1.82

RNA-seq

子宮:-

胎盤:-

前立腺:2.47

卵巣:0.85

精巣:0.90

心臓:0.78

骨格筋:0.03

食道:-

胃:-

腸:-

結腸:2.73

肝臓:2.45

肺:2.51

膀胱:-

腎臓:4.13

下垂体:-

甲状腺:2.36

副腎:1.03

膵臓:-

乳腺:0.59

唾液腺:-

IDs

Refseq ID	NM_005242
Gene ID	2150
Unigene ID	Hs.154299
Probe set ID	206429_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000164251
GTEx ID	ENSG00000164251

オーソログ対応遺伝子

マウス[1]	NM_007974
ラット [0]

染色体

5q13.3 [76,114,758 - 76,131,140]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR000276	7TM GPCR, rhodopsin-like
IPR017452	GPCR, rhodopsin-like superfamily
IPR002286	P2 purinoceptor
IPR003912	Protease-activated receptor
IPR002281	Protease-activated receptor 2

遺伝子オントロジー (GO ID)

Biological Process

GO:0007596	blood coagulation
GO:0090195	chemokine secretion
GO:0051607	defense response to virus
GO:0007204	elevation of cytosolic calcium ion concentration
GO:0007186	G-protein coupled receptor protein signaling pathway
GO:0006954	inflammatory response
GO:0045087	innate immune response
GO:0050702	interleukin-1 beta secretion
GO:0050900	leukocyte migration
GO:0070661	leukocyte proliferation
GO:0090198	negative regulation of chemokine secretion
GO:0046329	negative regulation of JNK cascade
GO:0034140	negative regulation of toll-like receptor 3 signaling pathway
GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway
GO:0042119	neutrophil activation
GO:0030836	positive regulation of actin filament depolymerization
GO:0030335	positive regulation of cell migration
GO:0050921	positive regulation of chemotaxis
GO:0002741	positive regulation of cytokine secretion during immune response
GO:0043311	positive regulation of eosinophil degranulation
GO:0070374	positive regulation of ERK1 and ERK2 cascade
GO:0003104	positive regulation of glomerular filtration
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0046330	positive regulation of JNK cascade
GO:0002690	positive regulation of leukocyte chemotaxis
GO:0070963	positive regulation of neutrophil mediated killing of gram-negative bacterium
GO:0060100	positive regulation of phagocytosis, engulfment
GO:0014068	positive regulation of phosphoinositide 3-kinase cascade
GO:0050927	positive regulation of positive chemotaxis
GO:0031274	positive regulation of pseudopodium assembly
GO:0035025	positive regulation of Rho protein signal transduction
GO:0032930	positive regulation of superoxide release
GO:0034137	positive regulation of toll-like receptor 2 signaling pathway
GO:0034141	positive regulation of toll-like receptor 3 signaling pathway
GO:0034145	positive regulation of toll-like receptor 4 signaling pathway
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0045909	positive regulation of vasodilation
GO:0030193	regulation of blood coagulation
GO:0043122	regulation of I-kappaB kinase/NF-kappaB cascade
GO:0046328	regulation of JNK cascade
GO:0002286	T cell activation during immune response

Cellular Component

GO:0005794	Golgi apparatus
GO:0005887	integral to plasma membrane
GO:0005886	plasma membrane
GO:0031143	pseudopodium

Molecular Function

GO:0001965	G-protein alpha-subunit binding
GO:0031681	G-protein beta-subunit binding
GO:0004930	G-protein coupled receptor activity
GO:0005515	protein binding
GO:0004872	receptor activity
GO:0005102	receptor binding
GO:0015057	thrombin receptor activity

coagulation factor II (thrombin) receptor-like 1

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function