fatty acid synthase

詳細情報を見る

同義遺伝子名

fatty acid synthase, Fatty acid synthase, FAS, OA-519, FASN, MGC14367, MGC15706

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:55.70 小脳:12.60 脳幹:- 脳梁:- 松果体:- 末梢神経:30.70 脊柱:561.50 網膜:- 目:205.70 動脈:- 静脈:- リンパ節:182 末梢血:18.20 脾臓:18.90 胸腺:- 骨髄:39.40 脂肪:403.30 骨:89.60 皮膚:398.40
GeneChip 大脳:8.01 小脳:8.63 脳幹:7.92 脳梁:8.09 松果体:- 末梢神経:8.74 脊柱:8.23 網膜:- 目:- 動脈:8.33 静脈:6.85 リンパ節:7.30 末梢血:- 脾臓:6.47 胸腺:7.20 骨髄:6.80 脂肪:11.14 骨:- 皮膚:8.41
CAGE 大脳:4.29 小脳:- 脳幹:4.70 脳梁:4.98 松果体:2.78 末梢神経:- 脊柱:4.01 網膜:- 目:- 動脈:3.83 静脈:5.17 リンパ節:4.15 末梢血:- 脾臓:2.91 胸腺:2.86 骨髄:- 脂肪:6.58 骨:- 皮膚:-
RNA-seq 大脳:3.69 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:3.21 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:5.70 骨:- 皮膚:-
EST 子宮:18.20 胎盤:21.90 前立腺:157.70 卵巣:74.50 精巣:26 心臓:12.80 骨格筋:80.40 食道:- 胃:85 腸:- 結腸:178.10     肝臓:-        肺:34.20    膀胱:- 腎臓:10.40 下垂体:- 甲状腺:- 副腎:50.80 膵臓:53.30 乳腺:278.80 唾液腺:-
GeneChip 子宮:6.72 胎盤:7.30 前立腺:8.38 卵巣:6.69 精巣:7.13 心臓:7.24 骨格筋:6.08 食道:7.98 胃:7.40 腸:6.92 結腸:7.45 肝臓:10.79 肺:7.54 膀胱:- 腎臓:6.70 下垂体:7.83 甲状腺:6.83 副腎:7.84 膵臓:6.59 乳腺:9.67 唾液腺:6.71
CAGE 子宮:3.10 胎盤:3.90 前立腺:4.21 卵巣:4.00 精巣:3.29 心臓:3.86 骨格筋:3.86 食道:4.93 胃:- 腸:3.45 結腸:4.74     肝臓:4.99    肺:5.24 膀胱:3.91 腎臓:3.16 下垂体:3.85 甲状腺:3.25 副腎:- 膵臓:3.13 乳腺:5.53 唾液腺:3.35
RNA-seq 子宮:- 胎盤:- 前立腺:3.08 卵巣:3.86 精巣:3.02 心臓:1.05 骨格筋:1.77 食道:- 胃:- 腸:- 結腸:2.30     肝臓:4.23        肺:2.93    膀胱:- 腎臓:1.86 下垂体:- 甲状腺:4.33 副腎:2.68 膵臓:- 乳腺:7.03 唾液腺:-

IDs

Refseq ID NM_004104
Gene ID 2194
Unigene ID Hs.83190
Probe set ID 212218_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000169710
GTEx ID ENSG00000169710

オーソログ対応遺伝子

マウス[1]  NM_007988
ラット[1]  NM_007988

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

600212
1044453
2669958
7567999
7595075
7835891
8022791
8662758
8944226
8986532
9356448
10769045
11018265
11034606
11248039
11756679
11790787
12060737
12213084
12477932
12515624
12531699
12646257
12689621
12815048
12839976
12882974
12939396
14689581
15047835
15050917
15113941
15161933
15220220
15235125
15254710
15302935
15489334
15507492
15523670
15576338
15669079
15852347
15897909
16009940
16175090
16189514
16196087
16210410
16215233
16263121
16335966
16582625
16644689
16806233
16894240
16964243
17081065
17081983
17188392
17220478
17488603
17492427
17618104
17618296
17620599
17631500
17662476
17687193
17847090
18022563
18029348
18211286
18239060
18281474
18281512
18410580
18420801
18455495
18528705
18635971
18660489
18682402
18682509
18781797
18796435
18802406
18820672
18830996
18838960
18955444
19027726
19032940
19056867
19083124
19135240
19252981
19300427
19318631
19358283
19380743
19467222
19471962
19517019
19542561
19543203
19621387
19728851
19738201
19847302
19851294
19876008
19885560
19893031
19913121
20067991
20126469
20132826
20228782
20299470
20356977
20360068
20511185
20546348
20602615
20606731
20628086
20657182
20679621
20691246
20691427
20811782
20877624
20965718
20972266
21044743
21081666
21145461
21252943
21319273
21325951
21360678
21442130
21641044
21646813
21726077
21726808
21757596
21877200
21890473
21906983
21908709
21922386
21963094
21970855
21987572
21988832
22053931
22127986
22135723
22145905
22178446
22266115
22268729
22370483
22412018
22425483
22490687
22505724
22536838
22586326
22653145
22723001
22771636
22786746
22863883
22939629
22990118
23000965
23040493
23064941
23084401
23125841
23135268
23142364
23184344
23184937
23208675
23269672
23306391
23317220
23402259
23419663
23427160
23438482
23455922
23675653
23725225
23862649
23887214
24105476
24108439
24200503
24250222
24337182
24390663
24457600
24583282
24596388
24639526
24654937

遺伝子オントロジー  (GO ID)

Biological Process

GO:0006084  acetyl-CoA metabolic process
GO:0044255  cellular lipid metabolic process
GO:0071353  cellular response to interleukin-4
GO:0006112  energy reserve metabolic process
GO:0006633  fatty acid biosynthetic process
GO:0006631  fatty acid metabolic process
GO:0015939  pantothenate metabolic process
GO:0031325  positive regulation of cellular metabolic process
GO:0019432  triglyceride biosynthetic process
GO:0006766  vitamin metabolic process
GO:0006767  water-soluble vitamin metabolic process

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0042587  glycogen granule
GO:0005794  Golgi apparatus
GO:0042470  melanosome
GO:0005739  mitochondrion
GO:0005886  plasma membrane

Molecular Function

GO:0047451  3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GO:0004317  3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity
GO:0004316  3-oxoacyl-[acyl-carrier-protein] reductase activity
GO:0004315  3-oxoacyl-[acyl-carrier-protein] synthase activity
GO:0008144  drug binding
GO:0004319  enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity
GO:0004312  fatty-acid synthase activity
GO:0016295  myristoyl-[acyl-carrier-protein] hydrolase activity
GO:0070402  NADPH binding
GO:0004320  oleoyl-[acyl-carrier-protein] hydrolase activity
GO:0016296  palmitoyl-[acyl-carrier-protein] hydrolase activity
GO:0005515  protein binding
GO:0042803  protein homodimerization activity
GO:0008270  zinc ion binding
GO:0004313  [acyl-carrier-protein] S-acetyltransferase activity
GO:0004314  [acyl-carrier-protein] S-malonyltransferase activity