fibroblast growth factor 2 (basic)

同義遺伝子名

HBGH-2, fibroblast growth factor 2 (basic), Heparin-binding growth factor 2 precursor, Prostatropin, BFGF, Basic fibroblast growth factor, HBGF-2, FGFB, FGF2

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:20.10

小脳:-

脳幹:-

脳梁:87.50

松果体:-

末梢神経:92

脊柱:-

網膜:-

目:41.10

動脈:30

静脈:-

リンパ節:30.30

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:40.30

骨:38.40

皮膚:144

GeneChip

大脳:4.37

小脳:4.15

脳幹:4.48

脳梁:4.40

松果体:-

末梢神経:4.54

脊柱:4.64

網膜:-

目:-

動脈:5.05

静脈:4.88

リンパ節:3.85

末梢血:-

脾臓:3.82

胸腺:3.83

骨髄:4.14

脂肪:4.99

骨:-

皮膚:4.35

CAGE

大脳:0.65

小脳:-

脳幹:0.85

脳梁:0.70

松果体:0.62

末梢神経:-

脊柱:1.09

網膜:-

目:-

動脈:0.87

静脈:0

リンパ節:0.23

末梢血:-

脾臓:0.17

胸腺:0.06

骨髄:-

脂肪:1.12

骨:-

皮膚:-

RNA-seq

大脳:3.76

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:2.28

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:3.31

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:665.30

胎盤:3.60

前立腺:-

卵巣:149.10

精巣:13

心臓:25.50

骨格筋:-

食道:-

胃:637.30

腸:64.80

結腸:-

肝臓:-

肺:24.40

膀胱:-

腎臓:41.60

下垂体:-

甲状腺:-

副腎:-

膵臓:35.60

乳腺:55.80

唾液腺:-

GeneChip

子宮:4.73

胎盤:4.29

前立腺:4.25

卵巣:4.77

精巣:3.85

心臓:4.52

骨格筋:4.35

食道:4.07

胃:4.31

腸:4.09

結腸:4.14

肝臓:3.80

肺:4.19

膀胱:-

腎臓:4.24

下垂体:4.02

甲状腺:3.90

副腎:3.97

膵臓:4.18

乳腺:4.25

唾液腺:4.14

CAGE

子宮:1.35

胎盤:0.16

前立腺:1.11

卵巣:1.43

精巣:0.53

心臓:0.63

骨格筋:0.09

食道:0.63

胃:-

腸:0.21

結腸:0.51

肝臓:0

肺:0.48

膀胱:1.24

腎臓:0.27

下垂体:0.10

甲状腺:0.57

副腎:-

膵臓:0

乳腺:0.90

唾液腺:0

RNA-seq

子宮:-

胎盤:-

前立腺:3.66

卵巣:3.44

精巣:2.19

心臓:1.47

骨格筋:1.12

食道:-

胃:-

腸:-

結腸:3.75

肝臓:0.56

肺:4.13

膀胱:-

腎臓:2.13

下垂体:-

甲状腺:1.59

副腎:2.35

膵臓:-

乳腺:4.32

唾液腺:-

IDs

Refseq ID	NM_002006
Gene ID	2247
Unigene ID	Hs.284244
Probe set ID	204421_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000138685
GTEx ID	ENSG00000138685

オーソログ対応遺伝子

マウス[1]	NM_008006
ラット [0]

染色体

4q27 [123,747,863 - 123,819,391]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR008996	Cytokine, IL-1-like
IPR002209	Heparin-binding growth factor/Fibroblast growth factor
IPR002348	Interleukin 1/heparin-binding growth factor

遺伝子オントロジー (GO ID)

Biological Process

GO:0000187	activation of MAPK activity
GO:0000186	activation of MAPKK activity
GO:0060128	adrenocorticotropin hormone secreting cell differentiation
GO:0006915	apoptosis
GO:0001658	branching involved in ureteric bud morphogenesis
GO:0006700	C21-steroid hormone biosynthetic process
GO:0002042	cell migration involved in sprouting angiogenesis
GO:0006935	chemotaxis
GO:0060591	chondroblast differentiation
GO:0048598	embryonic morphogenesis
GO:0007173	epidermal growth factor receptor signaling pathway
GO:0030198	extracellular matrix organization
GO:0008543	fibroblast growth factor receptor signaling pathway
GO:0010001	glial cell differentiation
GO:0030214	hyaluronan catabolic process
GO:0001759	induction of an organ
GO:0045087	innate immune response
GO:0032958	inositol phosphate biosynthetic process
GO:0008286	insulin receptor signaling pathway
GO:0030324	lung development
GO:0060644	mammary gland epithelial cell differentiation
GO:0043537	negative regulation of blood vessel endothelial cell migration
GO:0060548	negative regulation of cell death
GO:0030308	negative regulation of cell growth
GO:0008285	negative regulation of cell proliferation
GO:0010764	negative regulation of fibroblast migration
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0048011	nerve growth factor receptor signaling pathway
GO:0007399	nervous system development
GO:0000189	nuclear translocation of MAPK
GO:0009887	organ morphogenesis
GO:0006661	phosphatidylinositol biosynthetic process
GO:0048015	phosphoinositide-mediated signaling
GO:0050918	positive chemotaxis
GO:0045766	positive regulation of angiogenesis
GO:0043536	positive regulation of blood vessel endothelial cell migration
GO:0060045	positive regulation of cardiac muscle cell proliferation
GO:0051781	positive regulation of cell division
GO:0042660	positive regulation of cell fate specification
GO:0008284	positive regulation of cell proliferation
GO:0001938	positive regulation of endothelial cell proliferation
GO:0070374	positive regulation of ERK1 and ERK2 cascade
GO:0021940	positive regulation of granule cell precursor proliferation
GO:0045669	positive regulation of osteoblast differentiation
GO:0043552	positive regulation of phosphoinositide 3-kinase activity
GO:0010863	positive regulation of phospholipase C activity
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0007265	Ras protein signal transduction
GO:0045765	regulation of angiogenesis
GO:0051726	regulation of cell cycle
GO:0046668	regulation of retinal cell programmed cell death
GO:0051209	release of sequestered calcium ion into cytosol
GO:0048678	response to axon injury
GO:0007165	signal transduction
GO:0048864	stem cell development
GO:0021762	substantia nigra development
GO:0060129	thyroid stimulating hormone secreting cell differentiation
GO:0042060	wound healing

Cellular Component

GO:0005829	cytosol
GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0005634	nucleus

Molecular Function

GO:0042056	chemoattractant activity
GO:0005125	cytokine activity
GO:0017134	fibroblast growth factor binding
GO:0005104	fibroblast growth factor receptor binding
GO:0008083	growth factor activity
GO:0008201	heparin binding
GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
GO:0005515	protein binding

fibroblast growth factor 2 (basic)

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function