fibroblast growth factor receptor 2

同義遺伝子名

CD332, JWS, FGFR-2, ECT1, Keratinocyte growth factor receptor 2, TK25, CFD1, CEK3, TK14, BEK, CD332 antigen, KGFR, K-SAM, BFR-1, FGFR2, KSAM, Fibroblast growth factor receptor 2 precursor

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:68.70

小脳:100.80

脳幹:-

脳梁:-

松果体:-

末梢神経:490.80

脊柱:-

網膜:-

目:94

動脈:30

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:25.80

骨髄:19.70

脂肪:-

骨:64

皮膚:81.60

GeneChip

大脳:6.95

小脳:6.60

脳幹:7.27

脳梁:8.26

松果体:-

末梢神経:4.11

脊柱:8.09

網膜:-

目:-

動脈:4.49

静脈:4.58

リンパ節:4.71

末梢血:-

脾臓:3.98

胸腺:4.45

骨髄:3.89

脂肪:4.70

骨:-

皮膚:6.41

CAGE

大脳:3.89

小脳:-

脳幹:4.63

脳梁:5.13

松果体:1.12

末梢神経:-

脊柱:4.84

網膜:-

目:-

動脈:2.26

静脈:1.17

リンパ節:1.00

末梢血:-

脾臓:0

胸腺:1.29

骨髄:-

脂肪:1.01

骨:-

皮膚:-

RNA-seq

大脳:1.06

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:0

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:0.22

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:54.70

胎盤:32.80

前立腺:146.40

卵巣:-

精巣:26

心臓:38.30

骨格筋:-

食道:-

胃:-

腸:-

結腸:17

肝臓:42.20

肺:83.10

膀胱:-

腎臓:83.20

下垂体:116

甲状腺:-

副腎:50.80

膵臓:35.60

乳腺:46.50

唾液腺:-

GeneChip

子宮:6.70

胎盤:5.51

前立腺:6.71

卵巣:6.10

精巣:4.65

心臓:4.30

骨格筋:4.16

食道:5.94

胃:5.45

腸:5.74

結腸:5.88

肝臓:5.66

肺:4.72

膀胱:-

腎臓:5.83

下垂体:4.30

甲状腺:6.78

副腎:5.42

膵臓:6.01

乳腺:5.80

唾液腺:7.26

CAGE

子宮:3.24

胎盤:2.14

前立腺:2.77

卵巣:2.57

精巣:1.91

心臓:0.92

骨格筋:0.13

食道:2.68

胃:-

腸:2.12

結腸:3.11

肝臓:2.37

肺:3.23

膀胱:2.33

腎臓:3.13

下垂体:1.64

甲状腺:3.35

副腎:-

膵臓:3.02

乳腺:1.68

唾液腺:3.90

RNA-seq

子宮:-

胎盤:-

前立腺:0.50

卵巣:0.70

精巣:0.76

心臓:0.01

骨格筋:0.00

食道:-

胃:-

腸:-

結腸:1.77

肝臓:0.92

肺:0

膀胱:-

腎臓:0.58

下垂体:-

甲状腺:1.92

副腎:0.01

膵臓:-

乳腺:0.63

唾液腺:-

IDs

Refseq ID	NM_001144915
Gene ID	2263
Unigene ID	Hs.533683
Probe set ID	208228_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000066468
GTEx ID	ENSG00000066468

オーソログ対応遺伝子

マウス[3]	NM_010207, NM_201601
ラット[18]	NM_001109892, NM_001109893, NM_001109894, NM_001109895, NM_001109896, NM_012712

染色体

10q26.13 [123,237,848 - 123,357,972]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR013106	Immunoglobulin V-set
IPR003596	Immunoglobulin V-set, subgroup
IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

遺伝子オントロジー (GO ID)

Biological Process

GO:0001525	angiogenesis
GO:0006915	apoptosis
GO:0007409	axonogenesis
GO:0060348	bone development
GO:0030282	bone mineralization
GO:0060349	bone morphogenesis
GO:0060667	branch elongation involved in salivary gland morphogenesis
GO:0060670	branching involved in embryonic placenta morphogenesis
GO:0060442	branching involved in prostate gland morphogenesis
GO:0060445	branching involved in salivary gland morphogenesis
GO:0048755	branching morphogenesis of a nerve
GO:0060449	bud elongation involved in lung branching
GO:0045165	cell fate commitment
GO:0007267	cell-cell signaling
GO:0060365	coronal suture morphogenesis
GO:0048701	embryonic cranial skeleton morphogenesis
GO:0048557	embryonic digestive tract morphogenesis
GO:0048568	embryonic organ development
GO:0048562	embryonic organ morphogenesis
GO:0009880	embryonic pattern specification
GO:0007173	epidermal growth factor receptor signaling pathway
GO:0048730	epidermis morphogenesis
GO:0030855	epithelial cell differentiation
GO:0060664	epithelial cell proliferation involved in salivary gland morphogenesis
GO:0008543	fibroblast growth factor receptor signaling pathway
GO:0060595	fibroblast growth factor receptor signaling pathway involved in mammary gland specification
GO:0022612	gland morphogenesis
GO:0048565	gut development
GO:0031069	hair follicle morphogenesis
GO:0001701	in utero embryonic development
GO:0045087	innate immune response
GO:0042472	inner ear morphogenesis
GO:0008286	insulin receptor signaling pathway
GO:0032808	lacrimal gland development
GO:0060601	lateral sprouting from an epithelium
GO:0070307	lens fiber cell development
GO:0060174	limb bud formation
GO:0048286	lung alveolus development
GO:0030324	lung development
GO:0060463	lung lobe morphogenesis
GO:0060484	lung-associated mesenchyme development
GO:0060615	mammary gland bud formation
GO:0003149	membranous septum morphogenesis
GO:0048762	mesenchymal cell differentiation
GO:0060915	mesenchymal cell differentiation involved in lung development
GO:0060916	mesenchymal cell proliferation involved in lung development
GO:0030901	midbrain development
GO:0016331	morphogenesis of embryonic epithelium
GO:0035264	multicellular organism growth
GO:0008285	negative regulation of cell proliferation
GO:0045839	negative regulation of mitosis
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0048011	nerve growth factor receptor signaling pathway
GO:0021847	neuroblast division in the ventricular zone
GO:0007528	neuromuscular junction development
GO:0042476	odontogenesis
GO:0021769	orbitofrontal cortex development
GO:0035265	organ growth
GO:0009887	organ morphogenesis
GO:0030916	otic vesicle formation
GO:0003148	outflow tract septum morphogenesis
GO:0018108	peptidyl-tyrosine phosphorylation
GO:0048015	phosphoinositide-mediated signaling
GO:0060045	positive regulation of cardiac muscle cell proliferation
GO:0045787	positive regulation of cell cycle
GO:0051781	positive regulation of cell division
GO:0008284	positive regulation of cell proliferation
GO:0050679	positive regulation of epithelial cell proliferation
GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis
GO:0070374	positive regulation of ERK1 and ERK2 cascade
GO:0043410	positive regulation of MAPKKK cascade
GO:0002053	positive regulation of mesenchymal cell proliferation
GO:0010518	positive regulation of phospholipase activity
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0030177	positive regulation of Wnt receptor signaling pathway
GO:0009791	post-embryonic development
GO:0060527	prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis
GO:0060523	prostate epithelial cord elongation
GO:0060512	prostate gland morphogenesis
GO:0046777	protein amino acid autophosphorylation
GO:0021860	pyramidal neuron development
GO:0060687	regulation of branching involved in prostate gland morphogenesis
GO:0010453	regulation of cell fate commitment
GO:0070372	regulation of ERK1 and ERK2 cascade
GO:0040036	regulation of fibroblast growth factor receptor signaling pathway
GO:0060688	regulation of morphogenesis of a branching structure
GO:0040014	regulation of multicellular organism growth
GO:0045667	regulation of osteoblast differentiation
GO:0033688	regulation of osteoblast proliferation
GO:0051150	regulation of smooth muscle cell differentiation
GO:0008589	regulation of smoothened signaling pathway
GO:0048608	reproductive structure development
GO:0048705	skeletal system morphogenesis
GO:0060529	squamous basal epithelial stem cell differentiation involved in prostate gland acinus development
GO:0048489	synaptic vesicle transport
GO:0001657	ureteric bud development
GO:0055010	ventricular cardiac muscle tissue morphogenesis

Cellular Component

GO:0005938	cell cortex
GO:0009986	cell surface
GO:0005737	cytoplasm
GO:0016023	cytoplasmic membrane-bounded vesicle
GO:0060076	excitatory synapse
GO:0031012	extracellular matrix
GO:0005576	extracellular region
GO:0005794	Golgi apparatus
GO:0016021	integral to membrane
GO:0005887	integral to plasma membrane
GO:0016020	membrane
GO:0005634	nucleus
GO:0005886	plasma membrane

Molecular Function

GO:0005524	ATP binding
GO:0017134	fibroblast growth factor binding
GO:0005007	fibroblast growth factor receptor activity
GO:0008201	heparin binding
GO:0042802	identical protein binding
GO:0005515	protein binding
GO:0042803	protein homodimerization activity
GO:0004713	protein tyrosine kinase activity

fibroblast growth factor receptor 2

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function