fibroblast growth factor receptor 2

詳細情報を見る

同義遺伝子名

CD332, JWS, FGFR-2, ECT1, Keratinocyte growth factor receptor 2, TK25, CFD1, CEK3, TK14, BEK, CD332 antigen, KGFR, K-SAM, BFR-1, FGFR2, KSAM, Fibroblast growth factor receptor 2 precursor

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:68.70 小脳:100.80 脳幹:- 脳梁:- 松果体:- 末梢神経:490.80 脊柱:- 網膜:- 目:94 動脈:30 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:25.80 骨髄:19.70 脂肪:- 骨:64 皮膚:81.60
GeneChip 大脳:5.40 小脳:5.07 脳幹:5.57 脳梁:6.18 松果体:- 末梢神経:4.11 脊柱:6.06 網膜:- 目:- 動脈:4.54 静脈:4.21 リンパ節:4.34 末梢血:- 脾臓:4.15 胸腺:4.28 骨髄:4.25 脂肪:4.52 骨:- 皮膚:5.07
CAGE 大脳:3.89 小脳:- 脳幹:4.63 脳梁:5.13 松果体:1.12 末梢神経:- 脊柱:4.84 網膜:- 目:- 動脈:2.26 静脈:1.17 リンパ節:1.00 末梢血:- 脾臓:0 胸腺:1.29 骨髄:- 脂肪:1.01 骨:- 皮膚:-
RNA-seq 大脳:2.73 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:0.43 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:0 骨:- 皮膚:-
EST 子宮:54.70 胎盤:32.80 前立腺:146.40 卵巣:- 精巣:26 心臓:38.30 骨格筋:- 食道:- 胃:- 腸:- 結腸:17     肝臓:42.20        肺:83.10    膀胱:- 腎臓:83.20 下垂体:116 甲状腺:- 副腎:50.80 膵臓:35.60 乳腺:46.50 唾液腺:-
GeneChip 子宮:5.01 胎盤:4.33 前立腺:5.08 卵巣:4.87 精巣:4.35 心臓:4.30 骨格筋:4.49 食道:4.69 胃:4.62 腸:4.71 結腸:5 肝臓:4.59 肺:4.33 膀胱:- 腎臓:4.71 下垂体:4.41 甲状腺:4.77 副腎:4.56 膵臓:4.87 乳腺:4.50 唾液腺:5.42
CAGE 子宮:3.24 胎盤:2.14 前立腺:2.77 卵巣:2.57 精巣:1.91 心臓:0.92 骨格筋:0.13 食道:2.68 胃:- 腸:2.12 結腸:3.11     肝臓:2.37    肺:3.23 膀胱:2.33 腎臓:3.13 下垂体:1.64 甲状腺:3.35 副腎:- 膵臓:3.02 乳腺:1.68 唾液腺:3.90
RNA-seq 子宮:- 胎盤:- 前立腺:2.90 卵巣:1.77 精巣:1.15 心臓:0.00 骨格筋:0.05 食道:- 胃:- 腸:- 結腸:2.29     肝臓:0.53        肺:0.71    膀胱:- 腎臓:2.61 下垂体:- 甲状腺:1.45 副腎:0.73 膵臓:- 乳腺:0.42 唾液腺:-

IDs

Refseq ID NM_001144918
Gene ID 2263
Unigene ID Hs.533683
Probe set ID 211401_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000066468
GTEx ID ENSG00000066468

オーソログ対応遺伝子

マウス[3]  NM_010207, NM_201601
ラット[18]  NM_001109892, NM_001109893, NM_001109894, NM_001109895, NM_001109896, NM_012712

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

1309608
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遺伝子オントロジー  (GO ID)

Biological Process

GO:0001525  angiogenesis
GO:0006915  apoptosis
GO:0007409  axonogenesis
GO:0060348  bone development
GO:0030282  bone mineralization
GO:0060349  bone morphogenesis
GO:0060667  branch elongation involved in salivary gland morphogenesis
GO:0060670  branching involved in embryonic placenta morphogenesis
GO:0060442  branching involved in prostate gland morphogenesis
GO:0060445  branching involved in salivary gland morphogenesis
GO:0048755  branching morphogenesis of a nerve
GO:0060449  bud elongation involved in lung branching
GO:0045165  cell fate commitment
GO:0007267  cell-cell signaling
GO:0060365  coronal suture morphogenesis
GO:0048701  embryonic cranial skeleton morphogenesis
GO:0048557  embryonic digestive tract morphogenesis
GO:0048568  embryonic organ development
GO:0048562  embryonic organ morphogenesis
GO:0009880  embryonic pattern specification
GO:0007173  epidermal growth factor receptor signaling pathway
GO:0048730  epidermis morphogenesis
GO:0030855  epithelial cell differentiation
GO:0060664  epithelial cell proliferation involved in salivary gland morphogenesis
GO:0008543  fibroblast growth factor receptor signaling pathway
GO:0060595  fibroblast growth factor receptor signaling pathway involved in mammary gland specification
GO:0022612  gland morphogenesis
GO:0048565  gut development
GO:0031069  hair follicle morphogenesis
GO:0001701  in utero embryonic development
GO:0045087  innate immune response
GO:0042472  inner ear morphogenesis
GO:0008286  insulin receptor signaling pathway
GO:0032808  lacrimal gland development
GO:0060601  lateral sprouting from an epithelium
GO:0070307  lens fiber cell development
GO:0060174  limb bud formation
GO:0048286  lung alveolus development
GO:0030324  lung development
GO:0060463  lung lobe morphogenesis
GO:0060484  lung-associated mesenchyme development
GO:0060615  mammary gland bud formation
GO:0003149  membranous septum morphogenesis
GO:0048762  mesenchymal cell differentiation
GO:0060915  mesenchymal cell differentiation involved in lung development
GO:0060916  mesenchymal cell proliferation involved in lung development
GO:0030901  midbrain development
GO:0016331  morphogenesis of embryonic epithelium
GO:0035264  multicellular organism growth
GO:0008285  negative regulation of cell proliferation
GO:0045839  negative regulation of mitosis
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0048011  nerve growth factor receptor signaling pathway
GO:0021847  neuroblast division in the ventricular zone
GO:0007528  neuromuscular junction development
GO:0042476  odontogenesis
GO:0021769  orbitofrontal cortex development
GO:0035265  organ growth
GO:0009887  organ morphogenesis
GO:0030916  otic vesicle formation
GO:0003148  outflow tract septum morphogenesis
GO:0018108  peptidyl-tyrosine phosphorylation
GO:0048015  phosphoinositide-mediated signaling
GO:0060045  positive regulation of cardiac muscle cell proliferation
GO:0045787  positive regulation of cell cycle
GO:0051781  positive regulation of cell division
GO:0008284  positive regulation of cell proliferation
GO:0050679  positive regulation of epithelial cell proliferation
GO:0060501  positive regulation of epithelial cell proliferation involved in lung morphogenesis
GO:0070374  positive regulation of ERK1 and ERK2 cascade
GO:0043410  positive regulation of MAPKKK cascade
GO:0002053  positive regulation of mesenchymal cell proliferation
GO:0010518  positive regulation of phospholipase activity
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0030177  positive regulation of Wnt receptor signaling pathway
GO:0009791  post-embryonic development
GO:0060527  prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis
GO:0060523  prostate epithelial cord elongation
GO:0060512  prostate gland morphogenesis
GO:0046777  protein amino acid autophosphorylation
GO:0021860  pyramidal neuron development
GO:0060687  regulation of branching involved in prostate gland morphogenesis
GO:0010453  regulation of cell fate commitment
GO:0070372  regulation of ERK1 and ERK2 cascade
GO:0040036  regulation of fibroblast growth factor receptor signaling pathway
GO:0060688  regulation of morphogenesis of a branching structure
GO:0040014  regulation of multicellular organism growth
GO:0045667  regulation of osteoblast differentiation
GO:0033688  regulation of osteoblast proliferation
GO:0051150  regulation of smooth muscle cell differentiation
GO:0008589  regulation of smoothened signaling pathway
GO:0048608  reproductive structure development
GO:0048705  skeletal system morphogenesis
GO:0060529  squamous basal epithelial stem cell differentiation involved in prostate gland acinus development
GO:0048489  synaptic vesicle transport
GO:0001657  ureteric bud development
GO:0055010  ventricular cardiac muscle tissue morphogenesis

Cellular Component

GO:0005938  cell cortex
GO:0009986  cell surface
GO:0005737  cytoplasm
GO:0016023  cytoplasmic membrane-bounded vesicle
GO:0060076  excitatory synapse
GO:0031012  extracellular matrix
GO:0005576  extracellular region
GO:0005794  Golgi apparatus
GO:0016021  integral to membrane
GO:0005887  integral to plasma membrane
GO:0016020  membrane
GO:0005634  nucleus
GO:0005886  plasma membrane

Molecular Function

GO:0005524  ATP binding
GO:0017134  fibroblast growth factor binding
GO:0005007  fibroblast growth factor receptor activity
GO:0008201  heparin binding
GO:0042802  identical protein binding
GO:0005515  protein binding
GO:0042803  protein homodimerization activity
GO:0004713  protein tyrosine kinase activity