fms-related tyrosine kinase 4

詳細情報を見る

同義遺伝子名

PCL, FLT4, fms-related tyrosine kinase 4, VEGFR3, FLT41, VEGFR-3, Tyrosine-protein kinase receptor FLT4

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:- 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
GeneChip nodata
CAGE 大脳:0.73 小脳:- 脳幹:1.27 脳梁:1.19 松果体:0.92 末梢神経:- 脊柱:0.95 網膜:- 目:- 動脈:1.85 静脈:2.78 リンパ節:2.33 末梢血:- 脾臓:2.93 胸腺:0.18 骨髄:- 脂肪:2.95 骨:- 皮膚:-
RNA-seq 大脳:0.14 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:2.94 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:2.92 骨:- 皮膚:-
EST 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-
GeneChip nodata
CAGE 子宮:2.45 胎盤:4.22 前立腺:2.10 卵巣:2.14 精巣:1.72 心臓:2.16 骨格筋:1.36 食道:2.10 胃:- 腸:1.58 結腸:2.28     肝臓:2.47    肺:3.04 膀胱:2.20 腎臓:2.32 下垂体:1.59 甲状腺:2.70 副腎:- 膵臓:1.21 乳腺:3.69 唾液腺:1.00
RNA-seq 子宮:- 胎盤:- 前立腺:1.56 卵巣:1.57 精巣:1.49 心臓:0.88 骨格筋:0.08 食道:- 胃:- 腸:- 結腸:1.51     肝臓:1.27        肺:2.13    膀胱:- 腎臓:1.73 下垂体:- 甲状腺:2.46 副腎:4.32 膵臓:- 乳腺:1.40 唾液腺:-

IDs

Refseq ID NM_182925
Gene ID 2324
Unigene ID Hs.646917
Probe set ID -
Ensembl ID ENSG00000037280
GTEx ID ENSG00000037280

オーソログ対応遺伝子

マウス[2]  NM_008029
ラット[1]  NM_053652

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

遺伝子オントロジー  (GO ID)

Biological Process

GO:0048514  blood vessel morphogenesis
GO:0001945  lymph vessel development
GO:0001946  lymphangiogenesis
GO:0043066  negative regulation of apoptosis
GO:0018108  peptidyl-tyrosine phosphorylation
GO:0008284  positive regulation of cell proliferation
GO:0010595  positive regulation of endothelial cell migration
GO:0001938  positive regulation of endothelial cell proliferation
GO:0070374  positive regulation of ERK1 and ERK2 cascade
GO:0046330  positive regulation of JNK cascade
GO:0043410  positive regulation of MAPKKK cascade
GO:0001934  positive regulation of protein amino acid phosphorylation
GO:0090037  positive regulation of protein kinase C signaling cascade
GO:0010575  positive regulation vascular endothelial growth factor production
GO:0046777  protein amino acid autophosphorylation
GO:0060312  regulation of blood vessel remodeling
GO:0002040  sprouting angiogenesis
GO:0007169  transmembrane receptor protein tyrosine kinase signaling pathway
GO:0048010  vascular endothelial growth factor receptor signaling pathway
GO:0001944  vasculature development

Cellular Component

GO:0005737  cytoplasm
GO:0005576  extracellular region
GO:0005887  integral to plasma membrane
GO:0005634  nucleus
GO:0005886  plasma membrane

Molecular Function

GO:0005524  ATP binding
GO:0019838  growth factor binding
GO:0005515  protein binding
GO:0019903  protein phosphatase binding
GO:0004714  transmembrane receptor protein tyrosine kinase activity
GO:0005021  vascular endothelial growth factor receptor activity