arachidonate 12-lipoxygenase

詳細情報を見る

同義遺伝子名

12-LOX, Arachidonate 12-lipoxygenase, 12S-type, arachidonate 12-lipoxygenase, LOG12, ALOX12, Platelet-type lipoxygenase 12

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST nodata
GeneChip 大脳:4.52 小脳:4.49 脳幹:4.61 脳梁:4.36 松果体:- 末梢神経:4.40 脊柱:4.51 網膜:- 目:- 動脈:4.49 静脈:4.70 リンパ節:4.68 末梢血:- 脾臓:4.54 胸腺:4.38 骨髄:5.37 脂肪:4.61 骨:- 皮膚:5.85
CAGE 大脳:0.03 小脳:- 脳幹:0.07 脳梁:0 松果体:0 末梢神経:- 脊柱:0 網膜:- 目:- 動脈:0.34 静脈:0 リンパ節:1.01 末梢血:- 脾臓:0.51 胸腺:0 骨髄:- 脂肪:0 骨:- 皮膚:-
RNA-seq 大脳:0.10 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:0.26 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:0.32 骨:- 皮膚:-
EST nodata
GeneChip 子宮:4.61 胎盤:4.35 前立腺:4.24 卵巣:4.47 精巣:4.45 心臓:4.55 骨格筋:4.70 食道:8.64 胃:4.38 腸:4.61 結腸:4.67 肝臓:4.50 肺:4.31 膀胱:- 腎臓:4.66 下垂体:4.58 甲状腺:4.29 副腎:4.38 膵臓:4.49 乳腺:4.67 唾液腺:4.48
CAGE 子宮:2.16 胎盤:0.24 前立腺:0 卵巣:0 精巣:0.16 心臓:0.10 骨格筋:0 食道:3.06 胃:- 腸:0 結腸:0.04     肝臓:0    肺:0.10 膀胱:0.09 腎臓:0 下垂体:0 甲状腺:0 副腎:- 膵臓:0 乳腺:0 唾液腺:0
RNA-seq 子宮:- 胎盤:- 前立腺:0.21 卵巣:0.23 精巣:0.31 心臓:0.06 骨格筋:0.01 食道:- 胃:- 腸:- 結腸:0.25     肝臓:0.06        肺:1.07    膀胱:- 腎臓:0.26 下垂体:- 甲状腺:0.26 副腎:0.46 膵臓:- 乳腺:0.23 唾液腺:-

遺伝子オントロジー  (GO ID)

Biological Process

GO:0007568  aging
GO:0019369  arachidonic acid metabolic process
GO:0006928  cellular component movement
GO:0071396  cellular response to lipid
GO:0019395  fatty acid oxidation
GO:0051122  hepoxilin biosynthetic process
GO:0051121  hepoxilin metabolic process
GO:0019370  leukotriene biosynthetic process
GO:0043651  linoleic acid metabolic process
GO:0019372  lipoxygenase pathway
GO:0043066  negative regulation of apoptosis
GO:0010656  negative regulation of muscle cell apoptosis
GO:0045766  positive regulation of angiogenesis
GO:0043065  positive regulation of apoptosis
GO:0043280  positive regulation of caspase activity
GO:0045785  positive regulation of cell adhesion
GO:0030307  positive regulation of cell growth
GO:0030335  positive regulation of cell migration
GO:0008284  positive regulation of cell proliferation
GO:0045603  positive regulation of endothelial cell differentiation
GO:0010595  positive regulation of endothelial cell migration
GO:0010628  positive regulation of gene expression
GO:0051901  positive regulation of mitochondrial depolarization
GO:0048661  positive regulation of smooth muscle cell proliferation
GO:0045909  positive regulation of vasodilation
GO:0042554  superoxide anion generation

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0016020  membrane
GO:0042383  sarcolemma

Molecular Function

GO:0004052  arachidonate 12-lipoxygenase activity
GO:0051120  hepoxilin A3 synthase activity
GO:0047977  hepoxilin-epoxide hydrolase activity
GO:0005506  iron ion binding
GO:0016165  lipoxygenase activity
GO:0016702  oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GO:0005515  protein binding