gremlin 1, cysteine knot superfamily, homolog (Xenopus laevis)

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同義遺伝子名

Proliferation-inducing gene 2 protein, MGC126660, GREMLIN, PIG2, Down-regulated in Mos-transformed cells protein, DAND2, Cysteine knot superfamily 1, BMP antagonist 1, IHG-2, Gremlin-1 precursor, DRM, GREM1, gremlin, CKTSF1B1, Increased in high glucose protein 2

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:35.60 小脳:25.20 脳幹:- 脳梁:233.30 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:569.50 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:12.90 骨髄:846.30 脂肪:- 骨:627 皮膚:542.40
GeneChip 大脳:4.13 小脳:3.18 脳幹:3.72 脳梁:4.77 松果体:- 末梢神経:2.87 脊柱:4.12 網膜:- 目:- 動脈:3.48 静脈:5.77 リンパ節:3.95 末梢血:- 脾臓:2.84 胸腺:2.70 骨髄:2.84 脂肪:4.69 骨:- 皮膚:4.71
CAGE 大脳:2.98 小脳:- 脳幹:3.06 脳梁:3.51 松果体:0 末梢神経:- 脊柱:3.23 網膜:- 目:- 動脈:2.90 静脈:3.04 リンパ節:3.18 末梢血:- 脾臓:1.54 胸腺:0.06 骨髄:- 脂肪:3.12 骨:- 皮膚:-
RNA-seq 大脳:2.34 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:2.82 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:3.78 骨:- 皮膚:-
EST 子宮:209.60 胎盤:- 前立腺:- 卵巣:- 精巣:17.30 心臓:12.80 骨格筋:- 食道:- 胃:191.20 腸:97.20 結腸:110.20     肝臓:21.10        肺:78.20    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:17.80 乳腺:18.60 唾液腺:-
GeneChip 子宮:5.69 胎盤:2.80 前立腺:4.83 卵巣:2.89 精巣:2.84 心臓:3.21 骨格筋:3.02 食道:3.92 胃:7.51 腸:7.24 結腸:6.65 肝臓:2.89 肺:2.84 膀胱:- 腎臓:2.84 下垂体:2.80 甲状腺:3.16 副腎:2.99 膵臓:3.72 乳腺:5.46 唾液腺:2.81
CAGE 子宮:4.20 胎盤:0.68 前立腺:3.57 卵巣:1.97 精巣:1.24 心臓:1.48 骨格筋:1.78 食道:4.33 胃:- 腸:4.00 結腸:4.10     肝臓:1.41    肺:1.25 膀胱:4.84 腎臓:1.69 下垂体:0 甲状腺:1.83 副腎:- 膵臓:1.74 乳腺:4.09 唾液腺:0
RNA-seq 子宮:- 胎盤:- 前立腺:2.19 卵巣:0.47 精巣:0.54 心臓:0.04 骨格筋:0.00 食道:- 胃:- 腸:- 結腸:5.21     肝臓:0.38        肺:0.57    膀胱:- 腎臓:0.72 下垂体:- 甲状腺:0.92 副腎:3.17 膵臓:- 乳腺:0.60 唾液腺:-

遺伝子オントロジー  (GO ID)

Biological Process

GO:0006915  apoptosis
GO:0001658  branching involved in ureteric bud morphogenesis
GO:0002042  cell migration involved in sprouting angiogenesis
GO:0000902  cell morphogenesis
GO:0007267  cell-cell signaling
GO:0030199  collagen fibril organization
GO:0048263  determination of dorsal identity
GO:0030326  embryonic limb morphogenesis
GO:0003337  mesenchymal to epithelial transition involved in metanephros morphogenesis
GO:0030514  negative regulation of BMP signaling pathway
GO:0030502  negative regulation of bone mineralization
GO:0046851  negative regulation of bone remodeling
GO:0090191  negative regulation of branching involved in ureteric bud morphogenesis
GO:0030308  negative regulation of cell growth
GO:0090027  negative regulation of monocyte chemotaxis
GO:0033689  negative regulation of osteoblast proliferation
GO:0060394  negative regulation of pathway-restricted SMAD protein phosphorylation
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0090090  negative regulation of Wnt receptor signaling pathway through beta-catenin
GO:0045766  positive regulation of angiogenesis
GO:0090190  positive regulation of branching involved in ureteric bud morphogenesis
GO:0008284  positive regulation of cell proliferation
GO:0042346  positive regulation of NF-kappaB import into nucleus
GO:0051092  positive regulation of NF-kappaB transcription factor activity
GO:0002092  positive regulation of receptor internalization
GO:0051973  positive regulation of telomerase activity
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0003257  positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation
GO:0009954  proximal/distal pattern formation
GO:0010717  regulation of epithelial to mesenchymal transition
GO:0051893  regulation of focal adhesion formation
GO:0032872  regulation of stress-activated MAPK cascade
GO:0060676  ureteric bud formation

Cellular Component

GO:0009986  cell surface
GO:0005615  extracellular space

Molecular Function

GO:0005125  cytokine activity
GO:0016015  morphogen activity
GO:0005515  protein binding
GO:0030296  protein tyrosine kinase activator activity
GO:0048018  receptor agonist activity
GO:0043184  vascular endothelial growth factor receptor 2 binding