homeodomain interacting protein kinase 2

詳細情報を見る

同義遺伝子名

PRO0593, hHIPk2, homeodomain-interacting protein kinase 2, Homeodomain-interacting protein kinase 2, HIPK2, homeodomain interacting protein kinase 2

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:221.60 小脳:37.80 脳幹:- 脳梁:175 松果体:296.70 末梢神経:122.70 脊柱:- 網膜:355.90 目:164.60 動脈:89.90 静脈:- リンパ節:20.20 末梢血:- 脾臓:37.80 胸腺:38.70 骨髄:216.50 脂肪:40.30 骨:51.20 皮膚:105.60
GeneChip 大脳:8.03 小脳:6.88 脳幹:7.76 脳梁:9.57 松果体:- 末梢神経:6.04 脊柱:8.35 網膜:- 目:- 動脈:6.41 静脈:5.87 リンパ節:6.12 末梢血:- 脾臓:6.62 胸腺:5.03 骨髄:5.77 脂肪:6.64 骨:- 皮膚:5.71
CAGE 大脳:5.28 小脳:- 脳幹:5.71 脳梁:6.52 松果体:5.00 末梢神経:- 脊柱:5.52 網膜:- 目:- 動脈:4.19 静脈:4.04 リンパ節:4.12 末梢血:- 脾臓:4.51 胸腺:3.31 骨髄:- 脂肪:4.93 骨:- 皮膚:-
RNA-seq 大脳:4.64 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:2.66 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:3.50 骨:- 皮膚:-
EST 子宮:45.60 胎盤:51 前立腺:123.90 卵巣:37.30 精巣:26 心臓:114.90 骨格筋:60.30 食道:- 胃:63.70 腸:- 結腸:84.80     肝臓:52.80        肺:73.30    膀胱:125.60 腎臓:83.20 下垂体:232 甲状腺:163.70 副腎:253.90 膵臓:222.30 乳腺:158 唾液腺:-
GeneChip 子宮:5.50 胎盤:5.71 前立腺:6.32 卵巣:6.02 精巣:5.14 心臓:7.33 骨格筋:6.34 食道:6.84 胃:7.36 腸:6.28 結腸:6.34 肝臓:7.53 肺:6.69 膀胱:- 腎臓:7.95 下垂体:6.42 甲状腺:6.48 副腎:7.10 膵臓:6.77 乳腺:6.36 唾液腺:6.98
CAGE 子宮:3.65 胎盤:3.28 前立腺:3.98 卵巣:3.73 精巣:3.26 心臓:4.79 骨格筋:4.96 食道:3.81 胃:- 腸:3.98 結腸:3.83     肝臓:5.23    肺:4.48 膀胱:3.84 腎臓:5.05 下垂体:4.44 甲状腺:4.08 副腎:- 膵臓:3.82 乳腺:5.09 唾液腺:3.93
RNA-seq 子宮:- 胎盤:- 前立腺:1.08 卵巣:2.34 精巣:0.59 心臓:3.06 骨格筋:2.60 食道:- 胃:- 腸:- 結腸:1.93     肝臓:2.14        肺:1.59    膀胱:- 腎臓:3.81 下垂体:- 甲状腺:2.95 副腎:2.54 膵臓:- 乳腺:3.03 唾液腺:-

IDs

Refseq ID NM_001113239
Gene ID 28996
Unigene ID Hs.397465
Probe set ID 219028_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000064393
GTEx ID ENSG00000064393

オーソログ対応遺伝子

マウス[18]  NM_001136065, NM_010433
ラット[1]  NM_001108622, NM_010433

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

遺伝子オントロジー  (GO ID)

Biological Process

GO:0007628  adult walking behavior
GO:0009952  anterior/posterior pattern formation
GO:0071456  cellular response to hypoxia
GO:0042771  DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis
GO:0006978  DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
GO:0048596  embryonic camera-type eye morphogenesis
GO:0060059  embryonic retina morphogenesis in camera-type eye
GO:0030218  erythrocyte differentiation
GO:0001654  eye development
GO:0060235  lens induction in camera-type eye
GO:0030514  negative regulation of BMP signaling pathway
GO:0043524  negative regulation of neuron apoptosis
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0030182  neuron differentiation
GO:0018105  peptidyl-serine phosphorylation
GO:0018107  peptidyl-threonine phosphorylation
GO:0030578  PML body organization
GO:0045766  positive regulation of angiogenesis
GO:0008284  positive regulation of cell proliferation
GO:0043388  positive regulation of DNA binding
GO:0046330  positive regulation of JNK cascade
GO:0032092  positive regulation of protein binding
GO:0051091  positive regulation of transcription factor activity
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0030511  positive regulation of transforming growth factor beta receptor signaling pathway
GO:0006468  protein amino acid phosphorylation
GO:0051726  regulation of cell cycle
GO:0010842  retina layer formation
GO:0060395  SMAD protein signal transduction
GO:0007224  smoothened signaling pathway
GO:0007179  transforming growth factor beta receptor signaling pathway
GO:0019048  virus-host interaction
GO:0050882  voluntary musculoskeletal movement

Cellular Component

GO:0005813  centrosome
GO:0005737  cytoplasm
GO:0016604  nuclear body
GO:0031965  nuclear membrane
GO:0005634  nucleus
GO:0016605  PML body

Molecular Function

GO:0005524  ATP binding
GO:0005515  protein binding
GO:0004672  protein kinase activity
GO:0004674  protein serine/threonine kinase activity
GO:0046332  SMAD binding
GO:0003714  transcription corepressor activity
GO:0046790  virion binding