glutamate receptor, ionotropic, N-methyl D-aspartate 1

詳細情報を見る

同義遺伝子名

NR1, N-methyl-D-aspartate receptor subunit NR1, GRIN1, NMDA1, Glutamate [NMDA] receptor subunit zeta 1 precursor, NMDAR1

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:58.10 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:112.30 網膜:- 目:94 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
GeneChip 大脳:5.51 小脳:5.09 脳幹:5.21 脳梁:4.63 松果体:- 末梢神経:4.86 脊柱:4.94 網膜:- 目:- 動脈:4.82 静脈:4.63 リンパ節:4.60 末梢血:- 脾臓:4.53 胸腺:4.43 骨髄:4.82 脂肪:4.76 骨:- 皮膚:4.78
CAGE 大脳:6.01 小脳:- 脳幹:3.74 脳梁:4.05 松果体:0.91 末梢神経:- 脊柱:4.10 網膜:- 目:- 動脈:0.69 静脈:0.59 リンパ節:0.03 末梢血:- 脾臓:0 胸腺:0.06 骨髄:- 脂肪:0 骨:- 皮膚:-
RNA-seq 大脳:1.70 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:0 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:0 骨:- 皮膚:-
EST 子宮:- 胎盤:- 前立腺:11.30 卵巣:37.30 精巣:4.30 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:17.80 乳腺:- 唾液腺:-
GeneChip 子宮:4.43 胎盤:4.41 前立腺:4.62 卵巣:4.41 精巣:4.62 心臓:4.84 骨格筋:5.01 食道:4.55 胃:4.57 腸:4.78 結腸:4.91 肝臓:4.56 肺:4.49 膀胱:- 腎臓:4.68 下垂体:5.02 甲状腺:4.52 副腎:4.65 膵臓:5.17 乳腺:4.29 唾液腺:4.87
CAGE 子宮:0.19 胎盤:0.08 前立腺:0.08 卵巣:0.07 精巣:0.29 心臓:0 骨格筋:0 食道:0.26 胃:- 腸:0.07 結腸:0.64     肝臓:0    肺:0 膀胱:0.09 腎臓:0 下垂体:0.34 甲状腺:0 副腎:- 膵臓:0 乳腺:0 唾液腺:0.36
RNA-seq 子宮:- 胎盤:- 前立腺:0.01 卵巣:0 精巣:0.00 心臓:0 骨格筋:0.01 食道:- 胃:- 腸:- 結腸:0     肝臓:0        肺:0.03    膀胱:- 腎臓:0 下垂体:- 甲状腺:0 副腎:0 膵臓:- 乳腺:0.00 唾液腺:-

IDs

Refseq ID NM_021569
Gene ID 2902
Unigene ID Hs.558334
Probe set ID 205915_x_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000176884
GTEx ID ENSG00000176884

オーソログ対応遺伝子

マウス[2]  NM_001177656, NM_001177657, NM_008169
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

遺伝子オントロジー  (GO ID)

Biological Process

GO:0008344  adult locomotory behavior
GO:0055074  calcium ion homeostasis
GO:0006812  cation transport
GO:0006874  cellular calcium ion homeostasis
GO:0071287  cellular response to manganese ion
GO:0021987  cerebral cortex development
GO:0001661  conditioned taste aversion
GO:0035235  ionotropic glutamate receptor signaling pathway
GO:0007616  long-term memory
GO:0060179  male mating behavior
GO:0043524  negative regulation of neuron apoptosis
GO:0008355  olfactory learning
GO:0021586  pons maturation
GO:0043065  positive regulation of apoptosis
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0060134  prepulse inhibition
GO:0018964  propylene metabolic process
GO:0050770  regulation of axonogenesis
GO:0048814  regulation of dendrite morphogenesis
GO:0060079  regulation of excitatory postsynaptic membrane potential
GO:0048169  regulation of long-term neuronal synaptic plasticity
GO:0042391  regulation of membrane potential
GO:0043576  regulation of respiratory gaseous exchange
GO:0051963  regulation of synaptogenesis
GO:0007585  respiratory gaseous exchange
GO:0001975  response to amphetamine
GO:0051592  response to calcium ion
GO:0045471  response to ethanol
GO:0043278  response to morphine
GO:0048511  rhythmic process
GO:0019233  sensory perception of pain
GO:0035176  social behavior
GO:0001967  suckling behavior
GO:0007268  synaptic transmission
GO:0035249  synaptic transmission, glutamatergic
GO:0008542  visual learning

Cellular Component

GO:0030054  cell junction
GO:0009986  cell surface
GO:0030425  dendrite
GO:0032590  dendrite membrane
GO:0043197  dendritic spine
GO:0060076  excitatory synapse
GO:0005887  integral to plasma membrane
GO:0017146  N-methyl-D-aspartate selective glutamate receptor complex
GO:0043005  neuron projection
GO:0005886  plasma membrane
GO:0014069  postsynaptic density
GO:0045211  postsynaptic membrane
GO:0045202  synapse
GO:0043083  synaptic cleft
GO:0008021  synaptic vesicle
GO:0043195  terminal button

Molecular Function

GO:0005262  calcium channel activity
GO:0005509  calcium ion binding
GO:0005516  calmodulin binding
GO:0019899  enzyme binding
GO:0005234  extracellular-glutamate-gated ion channel activity
GO:0016595  glutamate binding
GO:0035254  glutamate receptor binding
GO:0016594  glycine binding
GO:0004972  N-methyl-D-aspartate selective glutamate receptor activity
GO:0042165  neurotransmitter binding
GO:0005515  protein binding
GO:0022843  voltage-gated cation channel activity