PYD and CARD domain containing

同義遺伝子名

PYD and CARD domain containing, Target of methylation-induced silencing 1, TMS1, MGC10332, PYCARD, ASC, hASC, CARD5, PYD and CARD domain-containing protein, Caspase recruitment domain-containing protein 5

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:1.20

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:23.50

動脈:-

静脈:133.30

リンパ節:30.30

末梢血:18.20

脾臓:-

胸腺:-

骨髄:19.70

脂肪:-

骨:-

皮膚:4.80

GeneChip

大脳:4.75

小脳:4.95

脳幹:5.13

脳梁:5.48

松果体:-

末梢神経:5.34

脊柱:5.57

網膜:-

目:-

動脈:5.84

静脈:5.56

リンパ節:7.33

末梢血:-

脾臓:7.02

胸腺:6.84

骨髄:7.56

脂肪:6.44

骨:-

皮膚:7.85

CAGE

大脳:1.65

小脳:-

脳幹:2.38

脳梁:2.82

松果体:0.98

末梢神経:-

脊柱:2.30

網膜:-

目:-

動脈:2.74

静脈:3.62

リンパ節:4.14

末梢血:-

脾臓:4.28

胸腺:3.67

骨髄:-

脂肪:3.30

骨:-

皮膚:-

RNA-seq

大脳:1.19

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:2.64

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:0.17

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:9.10

胎盤:14.60

前立腺:33.80

卵巣:-

精巣:4.30

心臓:-

骨格筋:-

食道:-

胃:-

腸:32.40

結腸:17

肝臓:-

肺:34.20

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:9.30

唾液腺:-

GeneChip

子宮:5.83

胎盤:5

前立腺:5.81

卵巣:6.25

精巣:4.42

心臓:5.23

骨格筋:4.78

食道:7.43

胃:5.85

腸:6.65

結腸:7.29

肝臓:5.24

肺:7.20

膀胱:-

腎臓:4.65

下垂体:4.88

甲状腺:5.37

副腎:5.24

膵臓:5.43

乳腺:7.27

唾液腺:5.89

CAGE

子宮:2.91

胎盤:2.70

前立腺:3.27

卵巣:2.82

精巣:2.03

心臓:2.33

骨格筋:1.38

食道:3.59

胃:-

腸:4.19

結腸:4.21

肝臓:2.68

肺:3.80

膀胱:2.73

腎臓:2.62

下垂体:1.27

甲状腺:2.54

副腎:-

膵臓:2.66

乳腺:3.02

唾液腺:3.29

RNA-seq

子宮:-

胎盤:-

前立腺:1.08

卵巣:2.01

精巣:1.61

心臓:0.51

骨格筋:0.13

食道:-

胃:-

腸:-

結腸:2.53

肝臓:0.33

肺:0.52

膀胱:-

腎臓:1.38

下垂体:-

甲状腺:0.58

副腎:3.03

膵臓:-

乳腺:2.20

唾液腺:-

IDs

Refseq ID	NM_145182
Gene ID	29108
Unigene ID	Hs.499094
Probe set ID	221666_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000103490
GTEx ID	ENSG00000103490

オーソログ対応遺伝子

マウス[2]	NM_023258
ラット[1]	NM_172322

染色体

16p11.2 [31,212,807 - 31,214,313]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR001315	Caspase Recruitment
IPR011029	DEATH-like
IPR004020	Pyrin

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

GO:0006919	activation of caspase activity
GO:0002218	activation of innate immune response
GO:0071347	cellular response to interleukin-1
GO:0071222	cellular response to lipopolysaccharide
GO:0071356	cellular response to tumor necrosis factor
GO:0050829	defense response to Gram-negative bacterium
GO:0051607	defense response to virus
GO:0042771	DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis
GO:0006917	induction of apoptosis
GO:0006954	inflammatory response
GO:0045087	innate immune response
GO:0032611	interleukin-1 beta production
GO:0001773	myeloid dendritic cell activation
GO:0002277	myeloid dendritic cell activation during immune response
GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB cascade
GO:0032688	negative regulation of interferon-beta production
GO:0032088	negative regulation of NF-kappaB transcription factor activity
GO:0030838	positive regulation of actin filament polymerization
GO:0042104	positive regulation of activated T cell proliferation
GO:0002821	positive regulation of adaptive immune response
GO:0002588	positive regulation of antigen processing and presentation of peptide antigen via MHC class II
GO:0043065	positive regulation of apoptosis
GO:0043280	positive regulation of caspase activity
GO:0090197	positive regulation of chemokine secretion
GO:0002230	positive regulation of defense response to virus by host
GO:0070374	positive regulation of ERK1 and ERK2 cascade
GO:0032729	positive regulation of interferon-gamma production
GO:0050718	positive regulation of interleukin-1 beta secretion
GO:0032755	positive regulation of interleukin-6 production
GO:0046330	positive regulation of JNK cascade
GO:0051092	positive regulation of NF-kappaB transcription factor activity
GO:0050766	positive regulation of phagocytosis
GO:0090200	positive regulation of release of cytochrome c from mitochondria
GO:0050870	positive regulation of T cell activation
GO:0051091	positive regulation of transcription factor activity
GO:0032760	positive regulation of tumor necrosis factor production
GO:0006508	proteolysis
GO:0031647	regulation of protein stability
GO:0032314	regulation of Rac GTPase activity
GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway
GO:0007165	signal transduction
GO:0033209	tumor necrosis factor-mediated signaling pathway

Cellular Component

GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005783	endoplasmic reticulum
GO:0005576	extracellular region
GO:0008385	IkappaB kinase complex
GO:0005739	mitochondrion
GO:0005634	nucleus

Molecular Function

GO:0008656	caspase activator activity
GO:0004197	cysteine-type endopeptidase activity
GO:0005515	protein binding
GO:0042803	protein homodimerization activity
GO:0032090	Pyrin domain binding

PYD and CARD domain containing

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function